A NOVEL APPROACH TO SYNTHESIZE CHITOSAN BEADS CROSSLINKED BY EPICHLOROHYDRIN

(整期优先)网络出版时间:2001-01-11
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Thepresentinvestigationdescribesanovelmethodforpreparingsphericalchitosanparticlesbasedoncrosslinkingwithepichlorohydrin.Certainamountofpre-crosslinkingagentwasaddedtoformchitosangelsbytraditionalinversephasesuspensionpolymerization.Thenthegelswerecrosslinkedbyepichlorohydrinatbasicconditiontoobtainchitosanbeads.Theeffectsofreactionconditions,suchascrosslinkingtime,theamountofcrosslinkingagentandtheNaOttconcentration,onthephysicalpropertiesofthechitosanbeadswereinvestigated.Thebeadswerefoundtohavemoreaminogroupsinthepolymerchainsthanthebeadscrosslinkedbyglutaraldehyde.Thecapacityforcopperionsisashighas40mg/g.Thebeadshavegoodmechanicalstrengthandcanbereused.