EROD activities of liver in Mugil so—iuy exposed to benzo(a)pyrene,pyrene and their mixture

(整期优先)网络出版时间:2003-02-12
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TheeffectsonhepaticEROD(7-ethoxyresorufinO-deethylase)inMugilso-iuyexposedtobenzo(a)pyrene(BaP),pyreneandtheirmixturesofequalconcentrationwereinvestigated,atconcentrationsof0.1,1.0,5.0,10.0,50.0μg/dm3,inexperimentalcondition.Time-effectsanddoseresponseofthebiochemicalindexswereobserved.TheresultsshowedthatthehepaticERODactivitieswereinducedbytheexposureofBaP,pyreneandtheirmixturesathighconcentration.Dose-responseconnectionswerethatthehepaticERODactivitieswereelevatedwithincreasingconcentrationofthepollutants.ThecombinedeffectofBaPandpyreneat1:1concentrationratioonhepaticERODactivitywasantagonism.