Atransientpostanaphaserepositioningofthecentrioleisfoundtocontrolthecompletionofcytokinesis.Usingagreenfluorescentprotein-calmodulinfusionproteinasalivingcellprobe,wehavepreviouslyfoundthatcalmodulinisassociatedwiththeinitiationandprogressionofcytokinesis.Inthisstudy,wefurtherstudiedtheeffectofcalmodulinontherepositioningofthecentrioleandsubsequentcellcycleprogression.Whenactivityofcalmodulinisinhibited,theregressionofthecentriolefromtheintercellularbridgetothecellcenterisblocked,andthusthecompletionofcellpisionisrepressedandtwodaughtercellsarelinkedbylongercellbridgeinperturbedcells.W7treatmentduringcytokinesisalsoresultsinunfinishedcytokinesisandstoppedG1phase.Theseresultssuggestthatcalmodulinactivityisrequiredforcentriolerepositioningandcanaffectthecompletionofcytokinesisandcellcycleprogression.