ObjectivesToquantitativelyanalyzethelongitudinalmyocardialsystolicanddiastolicvelocitiesandtimeintervalsoftheleftventricleinnormalsubjects,andtoexplorethevalueofpulsedDopplertissueimaging(DTI)fortheassessmentofleftventricularsystolicanddiastolicsynchronicity.MethodsTwentyandsixhealthysubjectswerestudiedbypulsedDTI.Theseptalandlateral,anteriorandinferiorwallsoftheleftventricleweredisplayedrespectively,andbasalandmiddlesegmentsofeachwallwereselectedformyocardialmotionspectrumsampling.DTIparameterswere;peaksystolicmyocardialvelocity(s),regionalpre-ejectionperiod(PEP),timetothepeakofswave(Ts),regionalejectiontime(ET);peakearlydiastolicvelocity(e),peaklatediastolicvelocity(a),e/aratio,timetothebeginningofewave(QE),timetothepeakofewave(Te)andregionalisovolumicrelaxationtime(IVRT).ResultsTheeande/aweresignificantlydifferentamongbasalsegments,andsande/aweresignificantlydifferentamongmiddlesegments,withthehighestvalueinlateralsegmentsandthelowestvalueinseptalsegments.Thes,eandawereallsignificandyhigherinbasalsegmentsthanmiddlesegments.Noneofthesystolictimeintervals(PEP,TsandET)anddiastolictimeintervals(QE,TeanpRT)weresignificantlydifferentamongbasalsegmentsandmiddlesegments,neitherweretheywhenbasalsegmentwascomparedwithmiddlesegment.ConclusionsInnormalsubjects,thelongitudinalmyocardialsystolicanddiastolicvelocitiesoftheleftventriclearenothomogeneous,butthecontractionandrelaxationarehighlysynchronized.PulsedDTIcanbeusedtoquantitativelyanalyzethesystolicanddiastolicsynchronicityoftheheart.
