简介：　　【摘要】 目的 综合分析早期乳腺癌保乳手术及改良根治术的临床疗效。方法 96例早期乳腺癌患者， 按照术式的不同分为实验组与对照组， 每组 48例。实验组患者行保乳术治疗， 对照组患者行改良根治术治疗。对两组患者的临床指标及并发症发生情况进行对比。结果 实验组患者的术中出血量（ 16.5±2.2） ml、手术时间（ 114.3±21.2） min、引流量（ 287.6±37.7） ml、住院时间（ 9.7±3.2） d均明显优于对照组的（ 48.1±2.0） ml、（ 156.2±22.7） min、（ 566.9±46.8） ml、（ 13.5±2.8） d， 差异具有统计学意义（ P<0.05）。实验组患者的并发症发生率 2.1%明显低于对照组的 14.6%， 差异具有统计学意义（ P<0.05）。结论 早期乳腺癌患者应用保乳手术的临床疗效显著， 不仅各项手术指标优于改良根治术， 且并发症的发生风险也低于改良根治术， 值得临床推广及应用。 

简介：　　【摘要】 目的：探讨甲状腺全切术治疗甲状腺癌的安全性和临床有效性。方法：抽取 2017年 3月 -2018年 12月在笔者所在医院治疗的甲状腺癌患者 120例作为研究对象，按国际随机数字表法分成两个研究组，即观察组和对照组，每组 60例。观察组患者采取甲状腺全切术进行治疗，对照组患者采取甲状腺次全切术或近全切术进行治疗。结果：观察组患者临床治疗总有效率为 95.00%，略高于对照组的 90.00%，但组间比较差异无统计学意义（字 2=1.638， P>0.05）。观察组患者手术时间短于对照组，术中出血量少于对照组，差异均有统计学意义（ t=38.532、 26.463， P<0.05）；两组患者住院时间比较差异无统计学意义（ t=1.452， P>0.05）。观察组患者甲状腺功能减退、喉返神经受损、低钙血症等并发症发生率均高于对照组，差异均有统计学意义（字 2=6.638、 14.687、 10.673， P<0.05）；但两组手足麻木发生率比较差异無统计学意义（字 2=1.153， P>0.05）。观察组患者复发率和二次手术率均为 0，均低于对照组，差异均有统计学意义（ X?=20.859、 22.521， P<0.05）。结论：相比甲状腺次全切术和近全切术而言，甲状腺全切术对甲状腺癌的治疗，不仅能够获得与之相当的临床疗效，同时在手术时间和术中出血量方面也具有显著优势，且其术后复发率和二次手术率显著较低；虽然甲状腺全切术的并发症发生率较高，但是其总体临床疗效优势显著。  　　【关键词】 甲状腺全切术； 甲状腺癌； 安全性； 有效性  [Abstract] Objective: To explore the safety and clinical effectiveness of total thyroidectomy in the treatment of thyroid cancer. Methods: 120 patients with thyroid cancer treated in our hospital from March 2017 to December 2018 were selected as research objects. According to the method of international random number table, they were divided into two research groups, namely observation group and control group, with 60 cases in each group. The patients in the observation group were treated by total thyroidectomy, while the patients in the control group were treated by subtotal thyroidectomy or near total thyroidectomy. Results: the total effective rate of the observation group was 95.00%, slightly higher than 90.00% of the control group, but there was no significant difference between the two groups (word 2 = 1.638, P > 0.05). The time of operation in the observation group was shorter than that in the control group, and the amount of bleeding in the operation was less than that in the control group, the difference was statistically significant (t = 38.532, 26.463, P < 0.05); there was no statistically significant difference in the length of stay between the two groups (t = 1.452, P > 0.05). The incidence of hypothyroidism, recurrent laryngeal nerve damage, hypocalcemia and other complications in the observation group were higher than that in the control group, the difference was statistically significant (word 2 = 6.638, 14.687, 10.673, P < 0.05), but there was no significant difference between the two groups in the incidence of hand and foot numbness (word 2 = 1.153, P > 0.05). The recurrence rate and secondary operation rate of the observation group were both 0, lower than that of the control group, and the difference was statistically significant (x? = 20.859, 22.521, P < 0.05). Conclusion: compared with subtotal thyroidectomy and near total thyroidectomy, total thyroidectomy can not only achieve the same clinical effect, but also has significant advantages in the operation time and intraoperative bleeding volume, and its postoperative recurrence rate and secondary hand operation rate are significantly lower; although the incidence of complications of total thyroidectomy is higher, its overall clinical effect is higher The bed curative effect superiority is remarkable.

简介：　　【摘 要】目的：分析原发性肝癌中晚期患者应用介入治疗对肝功能的影响。方法：我院 2017年 7月至 2019年 7月接收原发性肝癌中晚期患者 82例。采用随机分组原理分为对照组与观察组，两组均 41例。对照组采取常规方法治疗，观察组则应用介入方法治疗。对比分析临床效率与肝功能情况。结果：观察组与对照组治疗有效率分别为 92.7%与 82.9%，统计分析 P<0.05，符合统计学意义 ;相比较治疗前，治疗后两组患者 ALT、 ALB与 TBIL均改善，且观察组患者改善要显著优于对照组，符合统计学意义（ P<0.05）。结论：与临床常规方法相比较，介入治疗原发性肝癌中晚期患者可提高临床效率，改善患者肝功能，应用价值较高。  　　【关键词】介入治疗 ;原发性肝癌 ;肝功能  　 [Abstract] Objective: to analyze the effect of interventional therapy on liver function in patients with advanced primary liver cancer. Methods: from July 2017 to July 2019, our hospital received 82 patients with advanced primary liver cancer. According to the principle of random grouping, 41 cases were divided into control group and observation group. The control group was treated with conventional methods, while the observation group was treated with interventional methods. Comparative analysis of clinical efficiency and liver function. Results: the effective rate of treatment in the observation group and the control group was 92.7% and 82.9% respectively, statistical analysis P < 0.05, consistent with statistical significance; before treatment, the alt, ALB and TBIL in the two groups were improved, and the improvement in the observation group was significantly better than that in the control group, consistent with statistical significance (P < 0.05). Conclusion: compared with the routine clinical methods, interventional therapy can improve the clinical efficiency and liver function of patients with primary liver cancer.

简介：　　 [摘要 ] 目的 讨论对于结肠癌患者行改良右半结肠切除术治疗的临床疗效并对其进行安全性分析。方法 于 2017—2019年间在该院进行治疗的结肠癌患者中方便抽取 100例作为研究对象，对对照组患者行传统手术方式治疗，对试验组患者行改良右半结肠切除术治疗，对比观察两组患者的并发症出现率及相关手术指标。 结果 试验组患者的出现感染、脏器损伤及出血的癥状显著低于对照组患者，试验组患者的并发症感染、脏器损伤及出血出现率为 6.00%（ 3/50），对照组患者的并发症感染、脏器损伤及出血出现率为 28.00%（ 14/50），两组患者进行对比，组间差异有统计学意义（ χ2=8.576， P<0.05）。 结论 对结肠癌患者行改良半结肠切除术可以减轻患者的痛苦，减少患者术中出血量及手术操作时间，且临床疗效显著，患者的并发症出现较少，有效的减弱了患者术后癌细胞随淋巴扩散转移的几率，临床应用效果显著，值得推广。  　　 [关键词 ] 改良右半结肠切除术 ;结肠癌 ;临床效果  　 [Abstract] Objective To discuss the clinical efficacy and safety of modified right hemicolectomy for colon cancer. Methods from 2017 to 2019, 100 cases of colon cancer patients in the hospital were selected as the study object. The patients in the control group were treated with traditional surgical methods, and the patients in the test group were treated with modified right hemicolectomy. The incidence of complications and related surgical indicators were compared between the two groups. Result The symptoms of infection, organ injury and bleeding in the experimental group were significantly lower than those in the control group. The incidence of complication infection, organ injury and bleeding in the experimental group was 6.00% (3 / 50), and that in the control group was 28.00% (14 / 50). There was a significant difference between the two groups (χ 2 = 8.576, P < 0.05) ) Conclusion modified hemicolectomy can reduce the pain of patients with colon cancer, reduce the amount of bleeding and operation time, and the clinical effect is significant, the complications of patients are less, and effectively reduce the rate of cancer cell metastasis with lymph node diffusion after operation. The clinical application effect is significant, which is worth promoting.