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简介：Theeffectsofvariouscartilageextracellularmatrixontheconstructionofrabbitgrowthplatecartilagetissueinvitrowerestudied.Theresultsshowthatcollagen,proteoglycanandhyaluronicacidcanpromotethegrowthofculturedchondrocytesbuttheeffectsofvariouscartilageextracellularmatrix(ECM)onchondrocytedifferentiationaredifferent.Collagencanpromotethehypertrophyofchondrocyteswhileproteoglycanandhyaluronicacidinhibitthetransitionofmaturechondrocytesintohypertrophiedchondrocytes.
标签： EXTRACELLULAR matrix Tissue engineering cartilage Chondrocyte

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Construction of tissue engineered articular cartilage with the technique of centrifuge tube cultur

简介：INTRODUCTIONThecommonconstructionmethodoftissueengineeredarticularcartilageistoisolateandculturechondrocytes,transplantthemintothedegradablescaffoldmaterials,thentorepairthedefectofarticularcartilage.Wedesignedthisexperimenttoinvestigatethefeasibilityoftissueengineeredarticularcartilageconstructedbythetechniqueofcentrifugetubeculturewithoutscaffoldmaterials.
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Construction of tissue-engineered urinary bladder using biodegradable polymer matrices as cell scaffolds

简介：INTRODUCTIONApproximately400millionpersonsworldwidesufferfrombladderdisease.Individualswithend-stagebladderdiseaseoftenrequirebladderreplacementorrepair.Severalbladdersubstituteshavebeenattemptedwithbothorganicmaterialsandsynthetics.
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简介：IntroductionAsamemberofthebonemorphogeneticprotein(BMP)family,BMP-2playsimportantrolesnotonlyinboneregenerationandbonerepairbutalsoincellproliferation,apoptosis,differentiationandmorphogenesis.TheBMP-2remarkableabilitytostimulatenewbonegrowthresultsinthedevelopmentofanoveltherapystrategyforbonemassdefectduetoaccidentsordiseases.BecausetheBMP-2itself,inconjunctionwithasuitablematrix,issufficienttostimulategenesisofnewbone,thegeneticallyengineeredBMP-2hasgoodappliedprospects.
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