简介：INTRODUCTIONSincetheirintroductioninmid-1980s,polyamidoamide(PAMAM)dendrimershaveattractedconsiderableattentionbecauseoftheiruniquestructuresandproperties.Accordingtopreliminarystudiesinanimals,PAMAMdendrimersarenon-immunogenic,verylowinvivotoxicityandcanbeexcretedbyurineandfeces.

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简介：Inordertoimprovethehemostaticeffectivenessofethamsylateintreatmentofuppergastrointestinalhemorrhage,wehaddevelopedanewtypeofhemostaticdrug-oralandmagneticallycontrolledethamsylatemicrospheres(abbreviation:theetham-sylatemicrospheres)andtestedtheirparametersassociatedwithphysicalandchemi-calrespects.Itsmaincharacteristicsthatwefoundwere:1>Theethamsylatemi-

简介：Poly-α-aminoacidisakindofbiodegradablebiomedicalmaterial.Itisusedforthepreparationofsustaineddrug-releasedevice.Therearesomeadvantagesofthedrugdeliverydevices.Theycanprovidethetherapywithsideeffects.Thedrugre-leaseismaintainedatabeneficialrateforaprolongedtime.Thepolymermaybebiodegradedafterthedrughasbeenexhausted.

简介：Thepaperdescribesdrugreleaseevaluationofabiodegradablelong-actingcon-traceptiveCapsule(CaproF)containinglevonorgestrel(LNG)invivo.Poly(E-Capro-lactone)(PCL)biodegradablematerial,suitableformanymedicalapplication,wasusedinthisstudy.Itwasextrudedintotubes.ThetubeswerethencutandloadedwithLNGpowderbeforemelting-sealedonbothendstogetdrugcapsules.Thissub-dernalimplanthasbeenfoundtobehighlyeffectiveinanimalexperiments.Twoad-