简介：Abstract:ChlamydiaTrachomatis(C.T.)isoneofthemostcommonpathogensofhumansexuallytransmitteddiseases.TreatmentofC.T.infectionprimarilydependsonTetracyclines,MacrolidesandQuinolones,butwiththewideuseofantibioticsanincreasingnumberofdrug-resistantChlamydiatrachomatiscaseshavebeenreported.ThisreviewsummarizestheresistantconditionsandthepossibleresistancemechanismsofC.T..

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简介：Objective:Toinvestigatetheprevalenceofmycoplasmainfectionsandthesensitivitytoantibioticsamongpatientswithnongonococcalurethritisorcervicitis(NGU)inChongqing.Methods:387NGUcaseswithmycoplasma-positiveresultsuponculturewereanalysedretrospectively.RESULTS:Themajorityofpatientswithmycoplasmainfectionswereinthe20-40yearoldagegroup.Nosignificantdifferencewasfoundbetweenmalesandfemales.UreaplasmaurealyticumisthemainpathogenoftheseNGUcasesandnoclearrelationshipbetweenitsconcentrationandpathogenicabilitywasnoted.Drugsensitivitywastestedagainstnineantibiotics;thesensitivityratestojosamycin,minocyclineanddoxycyclinewere94.06%,88.89%and86.82%respectively,whiletheresistanceratestolincomycin,ofloxacin,azithromycinandroxthromycinwere74.94%,42.12%,41.60%and40.31%inturn.Conclusions:Josamycin,minocyclineanddoxycyclinecouldbeusedasthefirstchoicetotreatNGUwithmycoplasmainfectionsinChongqing.ItisimportanttoselectantibioticsforNGUtreatmentwithmycoplasmainfectionsbasedontheresultsofdrugsensitivitytests.

简介：Objective-TocomparetheconsistencyoftheresultsfromdetectingHIV-1antibodyinthepairedurineandserumspecimensfromdrugusersbyELISA.Methods:Thepairedurineandserumspecimensfrom273drugusersdetainedatadetoxificationunitwerecollected,andtheHIV-1antibodiesinthespecimensofthemwerescreenedbyurineandserumELISAkits,respectively.Results:Of273serumspecimens,94onesshowedpositivereactionandamong94counterparturinespecimens,93onesalsoappearedpositivereaction.Takingtheresultstogether,theconsistentrateofHIV-1antibodyscreenedbyurineandserumELISAkitswas99.6%.Conclusion:TheurineELISAkit,whichscreenedHIV-1antibodyofurineshowingalmostthesameresultstestedbyserumELISAkit,isreliable.ItisproposedthaturineELISAbeintroducedinmanyfields.