学科分类
/ 25
500 个结果
  • 简介:“2018823-25,国家卫生计生委医院管理研究所、中国科学技术大学附属第一医院、弗雷德·霍洛基金会、湖南爱眼公益基金会主办,中华医学会眼科学分会防盲学组、中国医师协会眼科医师分会防治视觉损伤专委会、中国非公立医疗机构协会眼科专业委员会、国际防盲协会、国际狮子会支持2018第二中国眼健康大会在安徽合肥圆满落幕。来自国内外650余位专家、学者及各界专业人士注册并参加。

  • 标签: 中国科学技术大学 眼健康 中国医师协会 非公立医疗机构 眼科医师 医院管理
  • 简介:胆脂瘤是一种能产生角蛋白鳞状上皮聚集于中耳、上鼓室、乳突、岩尖而形成,在中耳表现为独立生长、代替中耳黏膜、吸收骨质三维上皮结构。它不是一种肿瘤,但对患者有潜在危险。1829,法国Cruveilhier首先描述多中心白色“tumeursperlees”(瘤株),1838,Miiller第一个使用“cholesteatoma”(胆脂瘤)这一术语来描述颅内角化物堆积。1922,Cushing提出先天性胆脂瘤可能起源,1953,House报道经典鼓膜完整中耳胆脂瘤。事实上,胆脂瘤是一种良性角化上皮细胞囊,3种成分组成:囊内容、基质、基质外层。

  • 标签: 耳影像学 先天性胆脂瘤 CUSHING 临床 中耳黏膜 中耳胆脂瘤
  • 简介:AIM:Toinvestigatetheaccuracyofintraocularpressure(IOP)asmeasuredbyaReichertOcularResponseAnalyzer(ORA),aswellastherelationshipbetweencentralcornealthickness(CCT)andIOPasmeasuredbyORA,Goldmannapplanationtonometry(GAT),anddynamiccontourtonometry(DCT).·METHODS:Atotalof158healthyindividuals(296eyes)werechosenrandomlyformeasurementofIOP.AfterCCTwasmeasuredusingA-ultrasound(A-US),IOPwasmeasuredbyORA,GAT,andDCTdevicesinarandomizedorder.TheIOPvaluesacquiredusingeachofthethreetonometrieswerecompared,andtherelationshipbetweenCCTandIOPvalueswereanalyzedseparately.TwoIOPvalues,Goldmann-correlatedIOPvalue(IOPg)andcorneal-compensatedintraocularpressure(IOPcc),weregotusingORA.ThreegroupsweredefinedaccordingtoCCT:1)thincornea(CCT<520μm);2)normal-thicknesscornea(CCT:520-580μm);and3)thickcornea(CCT>580μm)groups.·RESULTS:Innormalsubjects,IOPmeasurementswere14.95±2.99mmHgwithORA(IOPg),15.21±2.77mmHgwithORA(IOPcc),15.22±2.77mmHgwithGAT,and15.49±2.56mmHgwithDCT.Meandifferenceswere0.01±2.29mmHgbetweenIOPccandGAT(P>0.05)and0.28±2.20mmHgbetweenIOPccandDC(P>0.05).TherewasagreatercorrelationbetweenIOPccandDCT(r=0.946,P=0.000)thanthatbetweenIOPccandGAT(r=0.845,P=0.000).DCThadasignificantcorrelationwithGAT(r=0.854,P=0.000).GATwasmoderatelycorrelatedwithCCT(r=0.296,P<0.001),whileIOPccshowedaweakbutsignificantcorrelationwithCCT(r=0.155,P=0.007).TherewasastrongnegativecorrelationbetweenCCTandthedifferencebetweenIOPccandGAT(r=-0.803,P=0.000),withevery10increaseinCCTresultinginanincreaseinthisdifferenceof0.35mmHg.Thethickcorneagroup(CCT>580μm)showedtheleastsignificantcorrelationbetweenIOPccandGAT(r=0.859,P=0.000);whilethethincorneagroup(CCT<520μm)hadthemostsignificantcorrelationbetweenIOPccandGAT(r=0.926,P=0.000).ThecorrelateddifferencesbetweenIOPccan

  • 标签: INTRAOCULAR PRESSURE TONOMETRY CENTRAL CORNEAL thickness
  • 简介:AIM:ToinvestigatetheregulationofEaf2proteininmouselenscellsapoptosisinducedbyultraviolet(UV)radiation.METHODS:AneyeofEaf2geneknockoutmiceornormalcontrolmicewasexposedtoUVradiation,andtheotheronewasnon-exposed.AlloflenseswereanalyzedbyTUNELandcaspase3activityassaystodeterminethedifferenceoftheapoptosisinducedbyUVradiation.Inaddition,exposedandnon-exposedlenseswereanalyzedbyquantifiedp53expressionandreal-timereversetranscription-polymerasechainreaction(RT-PCR)ofBax,Bid,Apaf-1,PumaandNoxa,tocompareEaf2geneknockoutmiceandnormalcontrolmice.RESULTS:UVradiationcausedapoptosisoflenscellsinnormalcontrolmiceandEaf2knockoutmice.Activityofcaspase3wassignificantlyhigherinnormalcontrolmicethanEaf2knockoutmice.Expressionofp53proteinwassignificantlyhigherinlensesexposedtoUVradiationthannonexposedlenses,butwassimilarbetweenEaf2geneknockoutmiceandnormalcontrolmiceinthesameUVcondition.AfterexposingtoUVradiation,theanalysisofreal-timeRT-PCRdemonstratedthatmRNAlevelsofPumaandNoxaweresignificantlyhigherinlensesofnormalcontrolmicethanEaf2geneknockoutmice,andthatmRNAlevelsofBax,BidandApaf-1werenotsignificantlydifferentbetweengeneknockoutmiceandnormalcontrolmice.CONCLUSION:Eaf2increaseslenscellsapoptosisinducedbyultravioletradiation.AndEaf2up-regulatesexpressionofthePumaandtheNoxatoactonlenscellsapoptosisafterUVradiation.

  • 标签: Eaf2 p53 APOPTOSIS NOXA PUMA ULTRAVIOLET
  • 简介:2010中华医学会眼科学分会防盲学组工作会议于2010827~28日在广州市远洋宾馆举行。参加本次会议有卫生部医政司综合处处长樊静,中华医学会眼科学分会防盲学组组长赵家良,副组长樊映川、管怀进、何明光、孙乃学,组员黄丽娜、贾亚丁、李建军、刘

  • 标签: 中华医学会 会议 防盲 学分 眼科 广州市
  • 简介:AIM:ToInvestigatetheeffectsoftransforminggrowthfactorβ2(TGF-β2)andconnectivetissuegrowthfactor(CTGF)ontransdifferentiationofhumanlensepithelialcells(HLECs)culturedinvitroandsynthesisofextracellularmatrix(ECM).METHODS:HLECsweretreatedwithTGF-β2(0,0.5,1.0,5,10μg/L)andCTGF(0,15,30,60,100μg/L)fordifferenttimes(0,24,48,72h)invitroandtheexpressionofα-smoothmuscleactin(α-SMA),themaincomponentoftheextracellularmatrixtypeⅠcollagen(Col-1)andfibronectin(Fn)weremeasuredbyusingreal-timepolymerasechainreaction(PCR)andwestern-blot.RESULTS:TGF-β2andCTGFsignificantlyincreasedexpressionofα-SMAmRNAandprotein(P<0.05,P<0.001),FnmRNAandprotein(P<0.001),Col-1mRNAandprotein(P<0.001).TGF-β2couldinduceHLECsexpressionofCTGFmRNAandproteinindosedependentmanner(P<0.05,P<0.001).TGF-β2andCTGFcouldinduceHLECstoexpressα-SMA,FnandCol-1intime-dependentmanner.EachtimeofTGF-β2andCTGFinducedHELCsexpressionofα-SMA,Fn,Col-1mRNAandproteinwassignificantincreasecomparedwithcontrol(P<0.05,P<0.001).CONCLUSION:TGF-β2andCTGFcouldinduceHLECsepithelialmesenchymaltransitionandECMsynthesis.

  • 标签: transforming GROWTH FACTOR β2 CONNECTIVE tissue
  • 简介:一种新型碳酸酐酶抑制剂(CAI):通过抑制睫状体中碳酸酐酶活性,减少房水生成减少房水流量,从而能有效降低眼内压。服用后一般在2—4小时内生效,在6-8小时内达到最佳疗效,10—18小时仍有效。

  • 标签: 醋甲唑胺 碳酸酐酶抑制剂 眼科 医药 合肥 降低眼内压
  • 简介:3.加强县级综合医院眼科能力建设,发挥其作为基层防盲治盲技术指导中心作用。鼓励城市三级医院眼科、眼科医院与县级综合医院眼科建立紧密合作关系,通过技术指导、人员培训等方式,使县级综合医院眼科具备常见眼病诊治急诊处理能力,落实双向转诊。

  • 标签: 防盲治盲 县级综合医院 眼科医院 急诊处理能力 能力建设 三级医院
  • 简介:AIM:Toinvestigatethediffusioncharacteristicsofwaterofopticnerveandopticradiationinhealthyadultsanditsrelatedfactorsbydiffusiontensorimaging(DTI)at3T.METHODS:Atotalof107healthyvolunteersperformedheadconventionalMRIandbilateralopticnerveandopticradiationDTI.TheprimarydataofDTIwasprocessedbypost-processingsoftwareofDTIstudio2.3,obtainingfractionalanisotropyvalue,meandiffusivityvalue,principalenginevalue,orthogonalenginevaluebymeasuring,andanalyzedbytheSPSS13.0statisticalsoftware.RESULTS:Thebilateralopticnerveandopticradiationfiberspresentedgreencolorindirectionalencodedcolor(DEC)mapsandpresentedhighsignalinfractionalanisotropy(FA)maps.TheFAvalueoftheleftopticnervewas0.598±0.069andtherightwas0.593±0.065;themeandiffusivity(MD)valueoftheleftopticnervewas(1.324±0.349)×10-3mm2/sandtherightwas(1.312±0.350)x10-3mm2/s;theprincipalenginevalue(λ?)oftheleftopticnervewas(2.297±0.522)×10-4mm2/sandtherightwas(2.277±0.526)×10-3mm2/s;theorthogonalenginevalue(λ⊥)oftheleftopticnervewas(0.838±0.285)×10-3mm2/sandtherightwas(0.830±0.280)×10-3mm2/s;theFAvalueoftheleftopticradiationwas0.636±0.057andtherightwas0.628±0.056;themeandiffusivity(MD)valueoftheleftopticradiationwas(0.907±0.103)×10-3mm2/sandtherightwas(0.889±0.125)×10-3mm2/s;theprincipaleigenvalue(λⅡ)oftheleftopticradiationwas(1.655±0.210)×10-3mm2/sandtherightwas(1.614±0.171)×10-3mn2/s;theorthogonalenginvalue(λ⊥)oftheleftopticradiationwas(0.531±0.103)×10-3mm2/sandtherightwas(0.524±0.152)×10-3m

  • 标签: magnetic resonance IMAGING diffusion TENSOR IMAGING
  • 简介:目的探讨健康体检中青光眼筛查方法及结果分析。方法采用同顾分析方法我院健康体检数据库资料进行分析。结果在121697健康体检中,发现青光眼1381例,患病率为1.14%,原发性闭角型青光眼(PACG)810例,患病率为0.67%,原发性开角型青光眼(POAG)476例,患病率为0.39%,正常眼压性青光眼(NTG)44例,患病率为0.04%,继发性青光眼(SG)51例、患病率为0。04%。正常大陷门者112例,术发现先天性青光眼。结论青光眼筛查方法应简易、快捷、价廉及有效健康体检作青光眼筛查足必要并且足可行,而且在健康体检数据中为所有受检建立健康档案,这对青光眼患者诊断、治疗及评估有十分重要意义,特别对可疑青光眼受检者有一个长期跟踪观察及对比机会。

  • 标签: 青光眼 筛查 健康体检
  • 简介:~~

  • 标签:
  • 简介:·AIM:Toreportvariousocularinjuriescausedbydurianfruit.·METHODS:Threecasesofocularinjuriesweredescribedinyoungpatients,duetoaccidentalfallofdurianfruitontheforeheadandface,whiletheyweretakingrest/sleeping/playingundertheduriantree.·RESULTS:Theocularinjuriesobservedwerelaceratinginjuryofcorneawithirisincarceration,hyphema,superficialpenetratinginjuryofscleraandanglerecessionglaucomaintherighteyeoffirstpatient;laceratinginjuryofcorneawithirisprolapseinthelefteyeofsecondpatient;subconjunctivalhaemorrhage,traumaticmydriasisandsuperficialpenetratinginjuryofsclera,commotionretinopathyandmacularedemainthelefteyeofthirdpatient.Visionimprovedtonormalinalltheeyesfollowingsurgical/medical/opticaltreatment.·CONCLUSION:Evidenceofpenetratinginjury(becauseofthorns)andbluntinjury(becauseofweight)canbeseenintheeyeswhendurianfruitfallsontheface.Visioncanberecoveredfullywithimmediateandappropriatetreatmentinthesecases.Theocularinjuriescanbepreventedbyeducatingthepublictowearprotectivemetalframewidegogglesandnottosleep/takerestundertheduriantree.

  • 标签: DURIAN FRUIT SUBCONJUNCTIVAL HAEMORRHAGE hyphema lacerating
  • 简介:本次会议中华医学会一类学术会议会议将以知识更新、讲座学术论文报告相结合形式进行学术交流。现将征文有关事项通知如下:一.征文内容眼科相关基础及临床研究、眼科管理、科研方法教学方面的研究论文或经验体会以及眼科录像、图片及绘图资料。

  • 标签: 中华医学会 学术会议 眼科 学术论文报告 征文内容 知识更新
  • 简介:<正>第十届全国眼外伤与眼成形学术会议,于19991011日至15日在广西北海市召开。本次学术会议中华眼科学会对学组进行调整,即眼成形专业加入眼外伤学组后第一全国性学术会议会议共收到眼外伤、职业眼病、眼成形及眼科手术方面的文章1100余篇,到会代表410。学组组长宋绣雯教授,副组长马志中、赵光熹教授到会并主持会议。眼外伤职业眼病学组创始及元老张效房教授、杨敬文所长、李

  • 标签: 眼外伤 全国性学术会议 北海市 成形 眼科手术 行调整