简介:AIM:ToexploretheeffectsofCompoundYi-Zhi(YZC)onlearningandmemorycapacityandfreeradicalmetabolisminD-galactoseinducedmicedementiamodel.METHODS:ThemicedementiamodelwasinducedbyadailyD-galactose0.15g/kgscfor45daysandafter5days'D-galactoseinjection,themiceweretreatedwiththreedosesofYZC
简介:Objective:ToexplorethemechanismofEcdysterone(ECR)inpreventionoflearningandmemorydysfunctionoftheratsinducedbyβ-amyloidpeptide(Aβ25-35).Methods:NinetyWistarmaleratswererandomlydividedintofivegroups,thecontrolgroup,themodelgroup,thetreatedgroups(ECR4mg·kg^-1andECR8mg·kg-1andNimodipine
简介:AIMToinvestigatetheeffectsofCapsuleYi-Zhi(CYZ)onlearningandmemorydisorderandbeta-amyloidproteininducedneurotoxieityinrats.MethodsVariousdosesofCYZwereadministeredtoSprague-Dawley(SD)ratsfor8days,twiceaday.Thenscopolaminehydrobromide(Sco)intraperitonealinjectionwasperformedoneachratandthe