简介：ComparisonsintheratesofstomachandcoloncancerbetweencountriesoftheEastandthoseoftheWestsuggestthatdietaryfactorsplayasignificantroleincarcinogenesisofthegastrointestinaltract.However,ithasbeendifficulttoclarifywhichofthemanyfactorsthatinfluencecarcinogenesisareinfactalteredbydiet.Geneticdeterminants,dietaryhabits,

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简介：Objective:Toexploretheriskfactorsofnosocomialinfectioninseverecraniocerebraltraumaandthewayofprevention.Methods:Theclinicaldataof387patientswithseverecraniocerebraltraumawerereviewed.Results:Thetotalnosocomialinfectionrateofthisstudywas22.99%.Pulmonarynosocomialinfectionpresentedmostfrequently.TheG-bacilliwerethemostcommoninfectiousbacteria.Themortalityrateoftheinfectiongroupwas38.20%.Conclusions:Complicationsofnosocomialinfectionaffecttheprognosisofcraniocerebraltraumapatients.Nosocomialinfectionisrelatedtotheageofthepatients,craniocerebraltraumaseverity,unreasonableutilizationofantibioticsandinvasiveoperations,suchastrachealcannula,mechanicalventilation,urethralcatheterizationanddeepvenouscatheterization.Patientswithseverecraniocerebraltraumashouldbecarefullytreatedandnursedtoavoidnosocomialinfection.Inordertoreducetherateofnosocomialinfection,intensivemeasurementshouldbeadopted.

简介：OjbectiveTofindtheindependentpredictorsforrestenosisaftercoronarystenting.MethodsQuantitativeangiographywasperformedon60cases(67successfullydilatedlesions)afterangio-plastyover6-monthsfollow-up,andbothunivariateandmultivariatelogisticregressionanalysisweredonetoi-dentifythecorrelationsofrestenosiswithclinicalfactors.ResultsThetotalrestenosisratewas31.3%(21of67lesions),andaccordingtounivariateanalysisthepatientswhounderwentcoronarystenting≥3.5mmhadalowerrateofrestenosis(P<0.01).Collateralcirculationtotheobstructionsite,highmaximalinflationpressure,smokingandthelessminimallumendiameterafterPTCAmadetherateofrestenosishigherower(P<0.05).Multivariatelogisticregressionanalysisshowedthatcoronarystenting≥3.5mmhadalowrateofrestenosis,buthighmaximalinflationpressureandsmokingmadetherestenosisratehigher.ConclusionCoronarystentsize,maximalinflationpressureand.smokin

简介：Inrecentyears'stagedagger'typeshamneedlinghasbeenanticipatedtobeoneofthepossiblesolutionsformaskingpatientsinacupunctureresearch.Inordertoassessthevalidityofthistypeofneedling,weconductedtworandomized,single-blind,cross-overtrialswithacupuncture-experiencedsubjects.

简介：Abstract5033farmerswereinterviewedtoparticipateinaclustersamplingsurveyonfactorsrelatedtotheHIV/AIDSepidemicinoneruralareainChina.Theresultsshowedthatfemalesattendedschoolforashortertimethanmales,maleshadahigherawarenessofHIV/AIDSandheldmorepositiveattitudestowardPLWHAs.Nearlyequalpercentagesofmenandwomenintheareasurveyed,soldblood.Elevenpercentmorementhanwomenhadahistoryofmigration.Condomusewasquitelowamongthesexuallyactivepopulationsurveyed.ResultsindicatedthataneducationcampaignonHIV/AIDSpreventioninruralareasshouldintegrategenderperspectivesandensurethattheinterventioncoverswomen.Futureinterventionsshouldbedesignedtotargetmaleandfemalemigration,andshouldfocusonmodifyingtheperceptionsofsocialnormsgoverninggenderrolesinadditiontoprovidingHIVpreventioninformationinordertocontaintheHIV/AIDSepidemicatitscurrentstageinChina.

简介：瞄准：与良性的职业人员静电干扰增生(BPH)在病人为职业人员静电干扰发炎程度和感染调查风险因素以便更高效地管理职业人员静电干扰发炎。方法：有在四川大学的韦斯特中国医院里经历在2005年9月和2005年12月之间的TURP的BPH的六十个病人被学习。前列腺液体(PF)为能分泌的IgA(SIgA)的测量被收集并且补充3(C3)。前列腺织物为由即时PCR的严峻的细菌的16SrDNA是镇定的，检验在织物的SIgA并且检验发炎。为职业人员静电干扰发炎或感染的可能的临床、有免疫力的风险因素被使用逻辑回归方法分析。结果：在尿分析法，职业人员静电干扰感染和在PF的C3的高集中的反常的白血房间计数是为职业人员静电干扰发炎程度的风险因素(P=0.025，0.034和0.035，分别地并且机会比率[或]=18.269，8.284和1.508，分别地)。为职业人员静电干扰感染的风险因素在PF包括C3集中和SIgA的集中(P=0.003和0.013，分别地并且OR=1.645并且0.993，分别地)。结论：现在的学习建议那职业人员静电干扰发炎与泌尿道感染，职业人员静电干扰感染和激活的补充被联系，那职业人员静电干扰感染与BPH在病人的前列腺与激活的补充并且在调整粘膜免疫下面被联系。单个有免疫力的规定应该与BPH在职业人员静电干扰发炎的治疗和病人的感染被考虑，这也被建议。

简介：Podophyllotoxone,4β-hydroxy-2,3-en-apopicropodophyllin,and4-deoxy-4β-azado-2,3-en-apo-picropodophyUincaneasilytransformto4-hydroxy-dehydropicropodophyUin,dehydroanhydropicropodophllyinand4-amino-dehydropicropodophyllinrespectivelyindifferentconditions.Thesepropertiesremind.ustobecarefulinhandlingrelatedcompoundsinsimilarconditions.

简介：Thestudyhasexplored11correlativevariableswhichmightaffectthegallblad-derpressureGBPofpatientswithgallstoneafterauricularelectricalstimulationbymeansofmultiplestepwiseregression.Itwasfoundthatthesizeofgallbladderstone(X9),cholecystolithiasis(X4),sex(X1),andthebaselineofGBP(X10)couldaffecttheGBPchangerange(Y1)depressinglyorreinforcingly.AlsothebaselineofGBP(Y1)couldbeaffectedbythevariablesX1(sex),X2(age),andX6(longdiameterofthegallbladder,LDGB),etc..TheresultshowsthatthechangeinGBPafterauricularelectricalstimulationiscomprehensivelyinfluencedbymultiplefactors.Anditprovidessomeusefulinformationforpredictingthecurativeeffectofauriculartherapyongallbladderstoneinclinic.

简介：用乳剂—溶剂挥发法制备硝苯地平的丙烯酸树脂缓释微球。微球中药物的释放速度随丙烯酸树脂ＥｕｄｒａｇｉｔＲＬ／ＲＳ比率的增加以及制备时搅拌速率的增加而增大，随内相聚合物浓度的增加及微球粒径的增加而减小，释药５０％所需时间与微球粒径呈良好线性。微球的释药速率也随药物含量的增加（从４．２％到１６．７％）而增大，并快于药物结晶的溶解速率，但药物含量达２６．６％时，微球释药速率明显下降并低于药物结晶的溶解速率。用差热分析和Ｘ射线衍射分析证明，药物含量为４．２，９．４和１６．７％的微球中药物完全是以非晶态分散的，而含药２６．６％的微球中有药物结晶存在。不同微球释药低于７０％时，释放方式均符合Ｈｉｇｕｃｈｉ时间平方根方程。

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简介：ObjectivesToevaluatetheeffectofdifferentstylesofcoronaryheartdisease(CHD),differentregionsofacutemyocardialinfarction(AMI),itsriskfactorsandbranchesofcoronarystenosisonleftventricularremodelinganddysfunctionbyapplyingechocardiography.Methods251patientswithCHDand96patientswithoutCHD(NoCHD)wereverifiedbyselectivecoronaryangiography.CHDpatientsweredividedintostableanginapectoris(SAP)26,unstableanginapectoris(UAP)53,acutemyocardialinfarction(AMI)140andoldmyocardialinfarction(OMI)30basedonclinicalsituation,cTnT,cardiacenzymeandEGG.AMIpatientswerefurtherdividedintosubgroupsincludingacuteanteriormyocardialinfarct(Aa,n=53),acuteinferiormyocardialinfarction(Ai,n,=54)andAa+Ai(n=33)basedonECG.Cardiacparameters:end-diastolicinterventricularseptumthickness(IVSd),end-diastolicleftventricularinternaldiameter(LVd),leftventricularmass(LM),end-diastolicleftventricularvolume(EDV),end-systolicleftventricularvolume(ESV)andleftventricularejectionfraction(LVEF)weremeasuredbyACUSON128XP/10echocardiography.MultipleslinearregressionanalyseswereperformedtoteststatisticalassociationsbetweenLVEFandtheinvolvedbranchesofcoronarystenosis,bloodpressure,lipids,glucoseandetcafteronsetofmyocardialinfarction.ResultsEDVandESVwereincreasedandLVEFdecreasedonpatientswithAMI,OMIandUAP(P<0.05-0.0001).LMwasmainlyincreasedinpatientswithOMI(P<0.01)andLVdwasmainlyenlargedinpatientswithAMI.EFwassignificantlydecreasedandEDV,ESV,LMandLVdwereremarkablyincreasedinAMIpatientswithAaandAa+Ai.WiththemultiplelinearregressionanalysesbySPSSsoftware,wefoundthatLVEFwasnegativelycorrelatedtotheinvolvedbranchesofcoronarystenosisaswellastosystolicbloodpressureafteronsetofmyocardialinfarctionwhiletherewasnosignificantcorrelationbetweenLVEFandotherfactors.LVEFwassignificantlydecreased,and

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简介：Objectives:Todescribeandanalyzeriskfactorsassociatedwithdisuseofcondomsduringcommercialsexualintercourseamongclientsattendingsaunaandmassagecenters.Methods:Selectedfemalesexworkersfromsaunasandbeautyparlorsweretrainedasinterviewers.Theysurveyedclientsduringprovisionofsexualservices.Informationcollectedincludedcustomers’demographics,knowledgeofSTDs,rationaleforandhistoryofcondomuse.Riskfactorsforcondomusagewereasessedthoughlogisticalmodeling.Results:Atotalof50clientswereinterviewed.Theratesofcondomusageforlastsexualintercoursewithcommercialandnon-commercialpartnerswere57%and53%forclientsofrespectively.Thechoicetouseacomdomwasinfluencedbyclients60.8%ofthetime,sexworkers30.4%,andotherfactors8.8%.Thechoiceagainstusingacondomwasdecideduponbyclients69.7%,ogthetime,sexworkers9.1%,andotherfactors21.2%.Multivariateanalysisshowedthateducationallevelandperceptionofriskofinfectionwerefactorsforcondomuse.Clientswithahighschooleducationhadahighercondomuseratethanthosewithamiddleschooleducationorless.Furthermore,clientswhoperceivedriskofdiseaseusedcomdomsmorefrequentlythanthosewhodidnot.Conclusions:Clientsplayedasignificantroleindecidingwhetherornottouseacondomduringcommercialsex,Lackofperceptionofriskisamajorfactorfornotusingcondoms.Aprogramforpromotionofprophylacticstargetingbothcommercialsexworkersandtheirclientsisrecommended.

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简介：Objective:Toassesstheincidence,typesandriskfactorsofmilitarytraining-relatedinjuriesinrecruitsofChinesePeople'sArmedPoliceForces(CPAPF).Methods:Acohortstudywasmadeontheriskfactorsofinjuriesin805malerecruitsduringthemilitarytrainingfromDecember25,1999toDecember25,2000.Results:Atotalof111recruits(14%)experiencedoneormoreinjuries,andthecumulativeincidencewas16.1injuries,andthecumulativeincidencewas16.1inujriesper100soldiersinayear.And77.7%oftheinjuriesbelongedtooveruseinjuriesoftheskeletalandmuscularsystems,themostcommontypeofwhichwasstressfractures.Mostinjuriesoccurredinthe3rdmonthoftraining.Univariateanalysisandlogisticregressionanalysisofpossibleriskfactorsforoveruseinjurieswerecarriedout,andanumberofriskfactorswereidentified:historyofagriculturallabor,historyoflowerlimbinjury,flatfootandlessrunningexercisebeforeentryintothearmy.Butasuitablebodymassindex(BMI)wasaprotectivefactor.Examinationofage,bodyheight,smoking,bodyflexibilityandfrequencyof2-milerunningrevealednosignificantassociationwiththeinjuries.Conclusions:Historyofagriculturallabor,historyoflowerlimbinjury,flatfoot,lessrunningexercisebeforeentryintothearmyandlowerBMIwereriskfactorsoftheoveruseinjuries.Inordertodecreasetheincidenceofoveruseinjuries,theyoungpeoplewithgoodphysicalabilityandshapelybodytypeshouldbeselectedduringconscription.Duringthetraining,nutritionshouldbeimprovedsoastodecreasetheincidenceofinjuries.

简介：Objectives:TodescribeandanalyzeHIV/AIDS/STD-relatedhighriskbehaviorsandaffectingfactorsofmenwhohavesexwithmen(MSM)inmainlandChina~Methods:426self-administeredorinterview-basedquestionnairescollectedfromMSMwereanalyzedwithSPSSorSASSystems.Results:OftheMSM,four-fifthshadengagedinoral-genitalintercourse,abouthalfhadengagedinanalintercourse,andinthepastyearmorethantwo-fifthshadcasualsexualpartner(s).Veryfewmaintainedmonogamoussexualrelationships,andnearlyhalfalsohadintercoursewithwomen.Onefourthhadpreviouslybeendiagnosedwithavenerealdiseases.OneHIV+individualwasfoundamongthe40whoreportedhavingbeentestedforHIV.Onlytwomenconsistentlyusedcondomsamongtheone-thirdwhohadeverusedcondoms,despitealmostuniversalknowledgeofHIVanditstransmission.Conclusions:MSMinmainlandChinaareverysexuallyactive,highlightingthepossibilityofaseriousHIVepidemicthatmaybedirectlyspreadtothefemalepopulation.However,AIDSinterventionstargetingMSMfacesevereobstructionsresultingfromculturalbiasandotherfactors.

简介：Objective:Theaimsofthiscross-sectionaldescriptivestudyweretoevaluatethequalityoflife(QoL)ofthelungcancerpatientsandtoinvestigatedifferencesinQoLwithrespecttogeneralandmedicalcharacteristics.Methods:Structuredquestionnaires(EORTCQLQ-C30andQLQ-LC13)wereusedamong106consecutivelungcancerpatientsfordatacollectionduring1Jan2002to31Dec2002.Thet-testandone-wayanalysisofvariance(ANOVA)wereusedtocomparedifferencesofQoLbetweenthefactorsata5%levelofsignificance.Results:Thestudyrevealedthatthequalityoflifeofthelungcancerpatientswereworsethanreferencevalue.Theyoung,maleandmarriedpatientgroupshadbetterQoL.PatientswithlowereducationorincomehadworseQoL.SmallcelllungcancerpatientsreportedpoorerQoLthannon-smallcelllungcancerpatients.ThequalityoflifeinpatientsatlatestageorwithmetastasishadworseQoL.Thetreatmentscouldworsenthequalityoflife.Whentheoutcomesofthefourtreatmentswerecompared,thesurgerygroupdisplayedthebestqualityoflifeandthecombinedtreatmentgroupdisplayedtheworstqualityoflife.Conclusion:Theresultsofthepresentstudyshowedimportantramificationsforclinicians,researchersandpolicy-makers.