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简介：ＣＬＩＮＩＣＡＬＲＥＰＯＲＴＯＦＭＯＤＩＦＩＥＤＭＡＺＥＰＲＯＣＥＤＵＲＥＣＬＩＮＩＣＡＬＲＥＰＯＲＴＯＦＭＯＤＩＦＩＥＤＭＡＺＥＰＲＯＣＥＤＵＲＥＺｈｕＪｉａＧｕａｎｇ；ＨｅＺｈｏｎｇＬｉａｎｇ；ＬｕｏＷｅｉ；ＤｏｎｇＡｉＱｉａｎｇ；ＸｕＳｈｉＷｅ...

简介：AbstractIntroduction:Histiocytoses are localized or systemic diseases that can broadly be classified into Langerhans cell histiocytosis and non-Langerhans cell histiocytosis. Juvenile Xanthogranuloma (JXG) belongs to the latter group, which occurs in around 0.5% population younger than 5 years, and presents as solitary or multiple lesions.Here, we present a case of disseminated JXG in an infant with the lesions regressing spontaneously.Case presentation:A 7-month-old boy presented with multiple erythematous nodular lesions over the body excluding limbs for 3 months. Initial laboratory work up was normal. Skin histopathology showed a dermal nodule with sheets of histiocytes exhibiting grooved vesicular nuclei and pale eosinophilic cytoplasm along with touton giant cells. Immunohistochemistry markers further confirmed the diagnosis. Lesions healed completely with symptomatic relief in 1.5 years and no recurrence occurred.Discussion:Disseminated JXG is a benign childhood disorder that can sometimes be associated with internal organs involvement mainly bones, eyes, and brain. Serious complications may follow in case of extracutaneous spread. Most frequently, JXG follows the occurrence of another neoplastic disorder but can sometimes appear de novo. Skin biopsy is required for the diagnosis and better education of the family.Conclusion:JXG in infancy is a rarity in South Asia. Therefore, along with the clinical judgment, clinicians must also get histological confirmation in order to manage this disorder successfully. Close surveillance for multiorgan involvement is also required to avoid any irreversible sequalae.

简介：AbstractIntroduction:Trichofolliculoma characterized clinically by the presence of acentral dilated pore with tufted hairs and corresponds histologically to a central primary follicle and many secondary vellus hair follicles originating from it. Thus far, dermoscopy description of trichofolliculoma has been lacking.Here, we describe a typical case of trichofolliculoma, particularly the special manifestation under the dermoscopy.Case presentation:A 29-year-old man complained a five-year history of a nodule containing a central whitish hair plug on his left tempus. Dermoscopic examination revealed a well-defined, yellow macule with a central whitish hair plug surrounded by dilated capillaries, and histopathological analysis was consistent with trichofolliculoma.Discussion:The findings of dermoscopy were also vary, which may be affected by the origin of the disease, various phases of the hair cycle, depth of the lesion, and even external stimulus.Conclusion:Diagnosis of trichofolliculoma is sometimes difficult because the presence of the central crater and visible hairs is low, and dermoscopy examination may be a potentially useful diagnostic tool.

简介：SYPHILIS1SCHARACTERIZEDbyseveralclinicalstages:primary,secondary,latentandtertiary.Duetothevarietyoflesionsthatmaypresentduringthesecondstage,syphilishasitsreputationofbeingthe"greatimpostor."Therefore,delaysinitsdiagnosisandtreatmentarecommonlyreported.

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简介：目的：观察针刺治疗失眠症的临床疗效。方法：86例失眠症患者，采用针刺为主治疗。每日1次，5天为1疗程，疗程间休息2d，4个疗程后统计疗效，并用匹兹堡睡眠质量指数（PittsburghSleepQualityIndex，PSQI）观察治疗前后的总积分。结果：总有效率为9514％，PSQI总积分治疗前后比较差异有统计学意义（P〈0．01）。结论：针剌治疗失眠症疗效确切，方法安全，可改善患者的生活质量和身体功能。

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简介：Haemangiopericytoma(HPC)isararevasculartumorwithborderlinemalignancy,considerablehistologicalvariability,andunpredictableclinicalandbiologicalbehavior.HPCcanpresentadiagnosticchallengebecauseofitsindeterminateclinical,radiological,andpathologicalfeatures.HPCgenerallypresentsinadulthoodandisequallyfrequentinbothsexes.HPCcanariseinanysiteinthebodyasaslowlygrowingandpainlessmass.TheprecisecelltypeoriginofHPCisuncertain.OnethirdofHPCsoccurintheheadandneckareas.Exceptionalcasesofhemangioblastomaarisingoutsidetheheadandneckareashavebeenreported,butlittleisknownabouttheirclinicopathologicandimmunohistochemicalfeatures.Thisstudyreportsonacaseofalargesacro-anteriorHPCina65-year-oldmale.

简介：AbstractThe Hoffa fracture is an uncommon fracture. There is a lot of confusion about its diagnosis and management with several conflicting reports in literature. We reported a 25-year-old patient with non-union of Hoffa fracture, and meanwhile tried to develop an algorithm-based treatment for Hoffa fractures. A systematic review of the available literature was performed. Medline, Embase, the Cochrane Library and PubMed were searched for relevant articles. Fifty-five articles were reviewed, and the clinical knowledge base was summarized. The understanding of the mechanism of trauma has become more nuanced. The literature has also evolved to classify the fracture with the purpose of surgical management in mind. This can be used to plan approach and fixation with preservation of blood supply. Classification can also prognosticate the outcomes in Hoffa fracture.

简介：AbstractIntroduction:Eruptive cutaneous collagenoma is non familial connective tissue nevi of unknown etiology presented with an abrupt onset. To date, the literatures on eruptive cutaneous collagenoma are extremely rare in china.Here, we report two women with eruptive cutaneous collagenoma.Case present:Two women presented with multiple asymptomatic, skin-colored papules and nodules on the trunk and extremities with no systemic involvement. Histopathology revealed dense, coarse collagen fibers by hematoxylin-esoin stain and decreased, fragmented elastic fibers by Elastic stain compared with the normal skin. Basing on these findings, the diagnosis of eruptive cutaneous collagenoma was made. No specific treatment was given.Discussion:Eruptive cutaneous collagenoma is a very rare dermatosis that is often misdiagnosed as other connective tissue nevi. The pathogenesis is unclear, and also no efficient treatment is available. It is usually diagnosed based on clinical and histopathological findings.Conclusion:The present cases are relatively rare type of eruptive cutaneous collagenoma that provide more experience for clinician, and may be helpful for them to make correct diagnosis for suspicious cases.

简介：AbstractPerimesencephalic subarachnoid hemorrhage (P-SAH) is a benign subset of subarachnoid hemorrhage. Only two cases of P-SAH during pregnancy have been reported in the literature. We describe a case of P-SAH detected at 29 weeks’ gestation, arose with severe bilateral frontal headache, neck rigidity, and vomiting. A diagnosis of P-SAH was confirmed on magnetic resonance angiography with no evidence of vascular malformation or bleeding sources and conservatively treated. Hemorrhage, vasospasm, and cerebellar edema observed on initial magnetic resonance angiography resolved after two months. The clinical course of P-SAH during pregnancy appears to be favorable. Our case shows for the first time in literature that magnetic resonance angiography is a valid diagnostic test for P-SAH during pregnancy that circumvents radiological risk associated with conventional imaging.

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简介：2CasesofMediterraneanspottedfeverinFrancewerereportedinthispaper.Bothhadtraveledintheendemicareasbeforeonset.Theirclinicalmanifestationsincludedfever,headache,myalgia,eruptionandblackeschar.SerologictestssuchasWeil-Felixreaction,Indirectimmunoflurescenceandcomplementfixationconfirmedthediagnosis.Thepatientsrecoveredwithoutcomplicationsandweredischargedfromhospitalaftereffectivetreatment.Simultaneously,theepidemiology,clinicaldiagnosis,treatmentandpreventionofthediseasewerereviewedandthepossibilityofthediseasebeingintroducedintothisterritorywasdiscussed.Theauthorheldthatattentionshouldbepaidtotheprophylaxisandtreatmentofthediseaseintheinternationaltravelhealthcare.

简介：Objective:Theototoxicityofpovidone-iodinehasbeendocumentedinanimalstudies.However,thereislimitedevidenceoftheseototoxiceffectsinhumans.Thisisthefirstreporttoshowtheototoxiceffectsofpovidoneiodineinahumansubject.Patient:A36-year-oldwomancametoourhospitalcomplainingofleftunilateralpersistenthearingloss.Onemonthbeforepresentation,herchildhadaccidentallystruckheronherleftear.Sheappliedapproximatelythreedropsofpovidone-iodine(10%weight/volume)intoherleftauditorycanal.Immediatelyafterapplication,shefeltseverepainandvertigo.Anaudiogramrevealedsevereleftunilateralsensorineuralhearingloss.Magneticresonanceimagingshowedmildenhancementoftheleftvestibuleandbasalturnoftheleftcochlea.Conclusions:Evenasingleapplicationofpovidone-iodinecouldcausesignificanthearinglossanddisequilibrium.Itshould,therefore,beusedwithcaution.

简介：ＡＣＡＳＥＲＥＰＯＲＴＯＦＰＲＩＭＡＲＹＳＱＵＡＭＯＵＳＣＡＲＣＩＮＯＭＡＯＦＴＨＥＥＮＤＯＭＥＴＲＩＵＭＨｅＷｅｎｃｕｉ何文翠；ＷｕＪｉｎｇ吴静；ＣｈａｎｇＪｉｅ唱捷；（ＴｈｅＳｅｃｏｎｄＡｆｆｉｌｉａｔｅｄＨｏｓｐｉｔａｌ，Ｘｉ’ａｎＭｅｄｉｃａ...

简介：Objective:Population-basedcancerregistrationdatain2010werecollected,evaluatedandanalyzedbytheNationalCentralCancerRegistry(NCCR)ofChina.Cancerincidentnewcasesandcancerdeathswereestimated.Methods:Therewere219cancerregistriessubmittedcancerincidenceanddeathdatain2010.AlldatawerecheckedandevaluatedonbasisofthecriteriaofdataqualityfromNCCR.Total145registries’datawerequalifiedandacceptedforcancerstatisticsin2010.Pooleddatawerestratifiedbyurban/rural,area,sex,agegroupandcancersite.Cancerincidentcasesanddeathswereestimatedusingage-specificratesandnationalpopulation.Thetoptencommoncancersindifferentgroups,proportionandcumulativeratewerealsocalculated.Chinesecensusin2000andSegi’spopulationwereusedforage-standardizedincidence/mortalityrates.Results:All145cancerregistries(63inurbanand82inrural)coveredatotalof158,403,248population(92,433,739inurbanand65,969,509inruralareas).Theestimatesofnewcancerincidentcasesandcancerdeathswere3,093,039and1,956,622in2010,respectively.Themorphologyverifiedcases(MV%)accountedfor67.11%and2.99%ofincidentcaseswereidentifiedthroughdeathcertificationsonly(DCO%)withmortalitytoincidenceratio(M/I)of0.61.Thecrudeincidenceratewas235.23/100,000(268.65/100,000inmales,200.21/100,000infemales),age-standardizedincidenceratesbyChinesestandardpopulation(ASIRC,2000)andbyworldstandardpopulation(ASIRW)were184.58/100,000and181.49/100,000withthecumulativeincidencerate(0-74yearsold)of21.11%.ThecancerincidenceandASIRCwere256.41/100,000and187.53/100,000inurbanareaswhereasinruralareas,theywere213.71/100,000and181.10/100,000,respectively.ThecrudecancermortalityinChinawas148.81/100,000(186.37/100,000inmalesand109.42/100,000infemales),age-standardizedincidenceratesbyChinesestandardpopulation(ASMRC,2000)andbyworldstandardpopulation(ASMRW)were113.92/100,000and112.86/100,0

简介：ＡＤＵＬＴＭＥＳＥＮＣＨＹＭＡＬＨＡＭＡＲＴＯＭＡＯＦＴＨＥＬＩＶＥＲ：ＡＣＡＳＥＲＥＰＯＲＴＷａｎｇＸｉａｎｇｈｕｉ王湘辉ＣｈａｉＦｕｌｕ柴福录ＤｏｎｇＬｉａｎｇ董亮ＬａｎｚｈｏｕＧｅｎｅｒａｌＨｏｓｐｉｔａｌｏｆＰＬＡ，Ｌａｎｚｈｏｕ７３００５０...