简介:Thispapermainlydiscussesthe"double-trackcharge"system(priceprejudicechargesystem)intheoryandpractice.Theauthorexplainsandanalyzesthe"differentialchargesphenomenon"ofuniversitiesinChinabytaking"Paretooptimality"asregulationstandardand"Darwinoptimality"asempiricalstandard,combiningregulationstandardwithpracticestandard,realisticstandardofvaluejudgmentwithultimatestandard,andfairnesswithefficiency.Thispaperprovidestheoreticalreferenceandanoperationplatformforapplicationandimplementationdifferentialchargesandthecontainmentofcorruptionincollegeenrollment.
简介:Overthepastdecades,cellsurfacecharge,althoughexperimentallyobserved,hasnotbeenwellunderstoodparticularlyfromtheviewpointofbiophysics.Ourrecentstudieshaveshownthatallcancercellsexhib让negativesurfacechargesthataredirectlyproportionaltothesecretedlacticacid,auniquecancermetaboliccharacteristic:highrateofglycolysis.Wehavethereforedesignedanddevelopedasetofelectrically-charged,fluorescent,andsuper-paramagneticnanoprobes,capableofsensitivedetectionofcancercellsbasedonthesurfacecharges.Theseprobesareutilizedtobindontocellsviaelectrostaticreactionforcaptureandmagneticseparation.Inthisfashion,weareabletocharacterizecellsurfacechargesthatareregulatedbydifferentmetabolicpatterns,thereforeeffectivelydistinguishingthecancercellsfromthenormalcells.All22cancercellsofdifferentorgansarefoundtobenegativelychargedthereforeboundstronglybythepositively-chargednanoprobes,whereasthenormalcellsshowinsignificantbindingtothenanoprobesofeitherchargesigns(positiveornegative).Thisfindingsuggeststhatalltestedcancercellsarenegatively-chargedandnormalcellsareeithercharge-neutralorslightlypositive.Fordiagnosis,cancercellscanbedetected,electrostaticallybound,andmagneticallyseparatedinbloodbychargedandsuper-paramagneticnanoprobes.Intherapeutics,circulatingcancercells(CTCs)canbefilteredandremovedinacontinuousfashiontoreducetheriskofcancermetastasis.Ifsuccessful,thisnewnanotechnologywillrevolutionizeearlycancerdiagnosisandpotentiallyenablenewtherapeuticsinclinicalsettings.
简介:AnewSOI(SiliconOnInsulator)highvoltagedevicewithStepUnmovableSurfaceCharges(SUSC)ofburiedoxidelayeranditsanalyticalbreakdownmodelareproposedinthepaper.Theunmovablechargesareimplementedintotheuppersurfaceofburiedoxidelayertoincreasetheverticalelectricfieldanduniformthelateralone.The2-DPoisson'sequationissolvedtodemonstratethemodulationeffectoftheimmobileinterfacechargesandanalyzetheelectricfieldandbreakdownvoltagewiththevariousgeometricparametersandstepnumbers.AnewRESURF(REduceSURfaceField)conditionoftheSOIdeviceconsideringtheinterfacechargesandburiedoxideisderivedtomaximizebreakdownvoltage.Theanalyticalresultsareingoodagreementwiththenumericalanalysisobtainedbythe2-DsemiconductordevicessimulatorMEDICI.Asaresult,an1200Vbreakdownvoltageisfirstlyobtainedin3μm-thicktopSilayer,2μm-thickburiedoxidelayerand70μum-lengthdriftregionusingalineardopingprofileofunmovableburiedoxidecharges.
简介:Themicroscopiceffectivechargesinmirrornuclei51Mnand51Feareinvestigatedwiththeparticle-vibrationcouplingmodelbasedontheself-consistentSkyrme-Hartree-Fockandcontinuumrandom-phase-approximationapproaches.Theisovectorpartsarepredictedtobearound0.15,andtheprotoneffectivechargesarearound1.25e,whichislessthantheempiricalvalueofeeffp=1.5e.Themicroscopiceffectivechargesinneutronrich51Mnareabout10%lessthanitsprotonrichmirror.TheseeffectivechargesarecombinedwiththeshellmodeltocalculatethereducedelectricquadrupoletransitionprobabilityB(E2)valuesin51Mnand51Fe.ItturnsoutthatthemicroscopiceffectivechargeshavewellreproducedtheB(E2)valuesanditsratiointheterminatingstates.