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简介：BackgroundAcuterespiratorydistresssyndrome(ARDS)causedbyH7N9influenzainpregnantwomanisalife-threateningeventwithanincreasedriskformaternalandbaby'sdeath.Theaimofthisstudywastoevaluatetheimpactofpoint-of-careultrasonography(POCUS)onthemanagementandprognosisofthesepatients.MethodsAcaseof31-yr-oldpregnantwomaninourhospital,whowasunderwentPOCUSforevaluatingcardiopulmonaryfunctions,volumestate,fluidresponsivenessandultrasound-guidedprocedureswasadmittedtoIntensiveCareUnit(ICU).Weperformedultrasonographydailyformonitoringorganfunctions.Reviewofrelatedliteratureswasalsoconducted.ResultsWiththehelpofPOCUS,wemadequicklydiagnosisofseverepneumoniaandARDScausedbyH7N9influenza.ThetherapieshadalsobeenchangedafterPOCUSexaminations,suchasrestrictfluidadministrationrelyingontheassessmentsoftheinferiorvenacava(IVC)toestimatepreloadandlungultrasoundmonitoringtoidentifytheearlypresenceofextravascularlungwater(EVLW)andavoidfluidoverresuscitation,ultrasound-guidedrecruitmentmaneuvertoimprovedrespiratorydistresssyndrome,andsoon.ConclusionsPOCUShasasignificantimpactondecision-makingandtherapeuticmanagementandshouldbecomeaclinicalroutineinthemanagementofARDSpatientscausedbyH7N9influenzainpregnancy.

简介：AbstractBackground:Zoonotic schistosomiasis, caused by Schistosoma japonicum, remains a major public health problem in the Philippines. This study aimed to evaluate the commercially available rapid diagnostic point-of-care circulating cathodic antigen (POC-CCA) test in detecting individuals infected with S. japonicum in a human cohort from an endemic area for schistosomiasis japonica in the Philippines.Methods:Clinical samples were collectedin 18 barangays endemic for S. japonicum infection in Laoang and Palapag municipalities, Northern Samar, the Philippines, in 2015. The presence of CCA in filter-concentrated urine samples (n = 412) was evaluated using the commercial kits and the results were converted to images, which were further analyzed by ImageJ software to calculate R values. The diagnostic performance of the immunochromatographic POC-CCA test was compared using the Kato-Katz (KK) procedure, in-house enzyme-linked immunosorbent assays (ELISAs) and droplet digital (dd) PCR assays as reference.Results:The POC-CCA test was able to detect S. japonicum-infected individuals in the cohort with an eggs per gram of faeces (EPG) more than or equal to 10 with sensitivity/specificity values of 63.3%/93.3%. However, the assay showed an inability to diagnose schistosomiasis japonica infections in all cohort KK-positive individuals, of which the majority had an extremely low egg burden (EPG: 1-9). The prevalence of S. japonicum infection in the total cohort determined by the POC-CCA test was 12.4%, only half of that determined by the KK method (26.2%). When compared with the ELISAs and ddPCR assays as a reference, the POC-CCA assay was further shown to be a test with low sensitivity. Nevertheless, the assay exhibited significant positive correlations with egg burden determined by the KK technique and the target gene copy number index values determined by the ddPCR assays within the entire cohort.Conclusions:By using in silico image analysis, the POC-CCA cassette test could be converted to a quantitative assay to avoid reader-variability. Because of its low sensitivity, the commercially available POC-CCA assay had limited potential for determining the status of a S. japonicum infection in the target cohort. The assay should be applied with caution in populations where schistosome parasites (especially S. japonicum) are present at low infection intensity.

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简介：ApresentstatusofthediagnosticsinEASTispresented.AsaveryimportantstepoftheEASTproject,tensofdiagnosticswereemployedforoperationandprotectionofthemachine,plasmacontrolandphysicsanalysistoaccommodaterequirementforthestudyonplasmaperformanceinEASTwithupgradedradiofrequency(RF)injectionpowerupto4MW(bothLHCDandICRF)intheforthcomingyears.Recently,newdiagnosticsaresetuptoprovideseveralprofilesofkeyplasmaparametersforthefurtherevaluationandbetterunderstandingoftheplasmaperformanceandphysicsinEAST,includinga25-channelThomsonscatteringsystemfordensityandelectrontemperature,ametalbolometryforradiatedpower,anX-raycrystalspectroscopyforbothionandelectrontemperaturesandplasmarotationvelocity,etc.Itisexpectedthatthesediagnosticswouldplayanimportantroleindataanalysisandinterpretationcombinedwithintegratedmodeling.

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简介：Aspectraldiagnosticsofcomplexareplasmausingmultiplespectralinformationofareself-emittingispro-posed.Thismethodisabletosimultaneouslydeterminecomponentdensities,thecorrespondingtemperatureandtheirdis-tributionsbyafewlineintensitiesmeasurent.Theprincipleofthemethodandtherelevantmeasuringsystemarede-scribed.Anequationsystemisestablishedforcomputationofthestatevariablesinareplasma.Anexperimentunderweldingareconditionismadeasanapplicationofthemethod.Theeffectsofprobableerrorsourcesonthemeasurementarealsoanalysed.

简介：Twodiagnosticsarepresentedforthetransformationofexplanatoryvariablesinregression.OneisbasedonthelikelihooddisplacementproposedbyCookandWeisberg(1982)forassessingtheinfluenceofindividualcasesonthemaximumlikelihoodestimateofatransformationparameter.Theotherisbasedonthelocalin-fluencetheoryproposedbyCook(1986)forassessingtheinfluenceofsmallperturba-tionsontheparameterestimates.Computationsarcperformedforadatasettoillus-tratetheusefulnessofthesediagnostics.

简介：InthispaperwereviewtheprovisionofthelaserdiagnosticsthatareinstalledontheVulcanlaserfacility.Wewillpresentstrategiesfordealingwiththeenergyofhighenergysystemsandwithwaysofhandlingthebeamsizesofthelasers.Wepresentdatacapturedduringtypicalexperimentalcampaignstodemonstratetheirreliabilityandvariationinshottoshotvalues.

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简介：careabout意为“关心；挂念；忧虑”。【经典例句】

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简介：AbstractFamily integrated care (FICare) is a collaborative model of neonatal care which aims to address the negative impacts of the neonatal intensive care unit (NICU) environment by involving parents as equal partners, minimizing separation, and supporting parent-infant closeness. FICare incorporates psychological, educational, communication, and environmental strategies to support parents to cope with the NICU environment and to prepare them to be able to emotionally, cognitively, and physically care for their infant. FICare has been associated with improved infant feeding, growth, and parent wellbeing and self-efficacy; important mediators for long-term improved infant neurodevelopmental and behavioural outcomes. FICare implementation requires multi-disciplinary commitment, staff motivation, and sufficient time for preparation and readiness for change as professionals relinquish power and control to instead develop collaborative partnerships with parents. Successful FICare implementation and culture change have been applied by neonatal teams internationally, using practical approaches suited to their local environments. Strategies such as parent and staff meetings and relational communication help to break down barriers to change by providing space for the co-creation of knowledge, the negotiation of caregiving roles and the development of trusting relationships. The COVID-19 pandemic highlighted the vulnerability within programs supporting parental presence in neonatal units and the profound impacts of parent-infant separation. New technologies and digital innovations can help to mitigate these challenges, and support renewed efforts to embed FICare philosophy and practice in neonatal care during the COVID-19 recovery and beyond.

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简介：Thispapermainlyinvestigatesplasmacharacterizationoncarbonfibercathodeswithandwithoutcesiumiodide(CsI)coatingpoweredbya～300ns,～200kVacceleratingpulse.ItwasfoundthattheCsIlayerscannotonlyimprovethediodevoltage,butalsomaintainastableperveance.Thisindicatesaslowlychangeddiodegaporalowcathodeplasmaexpansionvelocity.Byspectroscopicdiagnostics,inthevicinityofthecathodesurfacetheaverageplasmadensityandtemperaturewerefoundtobe～3×1014cm3and～5eV,respectively,foranelectroncurrentdensityof～40A/cm2.Furthermore,thereexistsamulticomponentplasmaexpansiontowardtheanode.Theplasmaexpansionvelocity,correspondingtothecarbonandhydrogenions,isestimatedtobe～1.5cm/μs.Mostnotably,Csspectroscopiclinewasobtainedonlyatthedistance≤0.5mmfromthecathodesurface.Carbonandhydrogenionsareobtaineduptothedistanceof2.5mmfromthecathodesurface.Csionsalmostremainatthevicinityofthecathodesurface.TheseresultsshowthattheadditionofCsIenablesaslowcathodeplasmaexpansiontowardtheanode,providingapositiveprospectfordevelopinglong-pulseelectronbeamsources.

简介：ThisisaphotographItookduringmytriptoSanya.Thatwasmyfirsttripbyair.Ihadbeenlookingforwardtobeingthereforalongtime.

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