简介：反应粉末水泥(RPC)的三种类型的影响行为用测试方法的裂口Hopkinson出版社酒吧(SHPB)被学习。这些RPC分别地与0%，3%，和4%的钢纤维体积部分被准备。压力紧张关系，紧张率敏感阀值价值，动态力量增加因素，弹性的模量和使遭到影响负担的这些RPC标本的失败模式被调查。从测试，50s1的紧张率敏感阀值价值被获得。试验性的结果看了那紧张率什么时候从阀值价值增加了到RPC的最大的压力增加了大约20%的95s1,，RPC的弹性的模量增加了大约30%。当使遭到了影响时，有钢纤维加强的RPC标本的失败模式与RPC矩阵标本的很不同装载。在装载率的类似的影响下面，在钢纤维开发的裂缝增强了RPC标本，虽然RPC矩阵标本被分解为小片。

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简介：Coloncancersdevelopadaptivemechanismstosurviveunderextremeconditionsanddisplayhallmarksofunlimitedproliferationandresistancetocelldeath.Thederegulationofcelldeathisakeyfactorthatcontri-butestochemoresistanceintumors.Inaphysiologicalcontext,balancebetweencellproliferationanddeath,andprotectionagainstcelldamagearefundamentalprocessesformaintaininggutepithelialhomeostasis.Themechanismsunderlyinganti-deathcytoprotectionandtumorresistanceoftenbearcommonpathways,andalthoughdistinguishingthemwouldbeachallenge,itwouldalsoprovideanopportunitytodevelopadvancedanti-cancertherapeutics.Thisreviewwilloutlinecelldeathpathways(i.e.,apoptosis,necrosis,andnecroptosis),anddiscusscytoprotectivestrategiesinnormalintestinalepitheliumanddeathresistancemechanismsofcolontumor.Incolorectalcancers,theintracellularmechanismsofdeathresistanceincludethedirectalterationofapoptoticandnecroptoticmachineryandtheupstreameventsmodulatingdeatheffectorssuchastumorsuppressorgeneinactivationandpro-survivalsignalingpathways.Theautocrine,paracrineandexogenousfactorswithinatumormicroenvironmentcanalsoinstigateresistanceagainstapoptoticandnecroptoticcelldeathincoloncancersthroughchangesinreceptorsignalingortransporteruptake.Therolesofcyclooxygenase-2/prostaglandinE2,growthfactors,glucose,andbacteriallipopolysaccharidesincolorectalcancerwillbehighlighted.Targetinganti-deathpathwaysinthecoloncancertissuemightbeapromisingapproachoutsideofanti-proliferationandanti-angiogenesisstrategiesfordevelopingnoveldrugstotreatrefractorytumors.

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简介：Theshiphullsurfaceoptimizationbasedonthewaveresistanceisanimportantissueintheshipengineeringindustry.Thewaveletmethodmayprovideaconvenienttoolforthesurfacehulloptimization.Asapreliminarystudy,weusethewaveletmethodtooptimizethehullsurfacebasedontheMichelwaveresistanceforaWigleymodelinthispaper.Firstly,weexpressthemodel’ssurfacebythewaveletdecompositionexpressionsandobtainareconstructedsurfaceandthenvalidateitsaccuracy.Secondly,werewritetheMichelwaveresistanceformulainthewaveletbases,resultinginasimpleformulacontainingonlytheshiphullsurface’swaveletcoefficients.Thirdly,wetakethesewaveletcoefficientsasoptimizationvariables,andanalyzethemainwaveresistancedistributionintermsofscalesandlocations,toreducethenumberofoptimizationvariables.Finally,weobtaintheoptimalhullsurfaceoftheWigleymodelthroughgeneticalgorithms,reducingthewaveresistancealmostbyahalf.Itisshownthatthewaveletmethodmayprovideanewapproachforthehulloptimization.

简介：Ballisticthermalresistanceofgraphenenano-junctionsisinvestigatedusingnon-equilibriummoleculardynamicssimulation.Thesimulationsystemisconsistedoftwosymmetricaltrapezoidalorrectangulargraphenenanoribbons(GNRs)andaconnectingnanoscaleconstrictioninbetween.Fromthesimulatedtemperatureprofile,abigtemperaturejumpresultedfromtheconstrictionisfound,whichisproportionaltotheheatcurrentandcorrespondstoalocalballisticthermalresistance.FixingtheconstrictionwidthandthelengthofGNRs,thisballisticthermalresistanceisindependentofthewidthoftheGNRsbottomlayer,i.e.,theconvexangle.Butinterestingly,thisthermalresistancehasobvioussizeeffect.Itisinverselyproportionaltotheconstrictionwidthandwilldisappearwiththeconstrictionbeingwider.Moreover,basedonthephonondynamicstheory,atheoreticalmodeloftheballisticthermalresistanceintwo-dimensionalnano-systemsisdeveloped,whichgivesagoodexplanationonmicrocosmiclevelandagreeswellwiththesimulationresultquantitativelyandqualitatively.

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简介：Thecombinationofdeepwetetchingandamagneto-rheologicalfinishing(MRF)processisinvestigatedtosimultaneouslyimprovelaserdamageresistanceofafused-silicasurfaceat355nm.ThesubsequentlydepositedSiO2coatingsareresearchedtoclarifytheimpactofsubstratefinishingtechnologyonthecoatings.Itisrevealedthatadeepremovalproceedingfromthesinglesideordoublesidehadasignificantimpactonthelaser-induceddamagethreshold(LIDT)ofthefusedsilica,especiallyfortherearsurface.Afterthedeepetching,theMRFprocessthatfolloweddoesnotactuallyincreasetheLIDT,butitdoesamelioratethesurfacequalitieswithoutadditionalLIDTdegradation.Thecombinationguaranteeboththeintegrityofthesurface’sfinishandthelaserdamageresistanceofthefusedsilicaandsubsequentSiO2coatings.

简介：TheChineseAnti-JapaneseWarwasabattlebetweenhumanrightsprotectionsandabuses,betweencivilizationandbrutality,andbetweenjusticeandevil.Duringthewar,thehumanrightsofChinesepeoplewerecompletelyviolatedbytheJapaneseaggressors,causinganunprecedentedhumanrightscatastrophe.Atthesametime,Chinesepeoplevigorouslyresistedtheaggressioninordertodefendthenationalsurvivalrightandsafeguardthehumanpeaceagainstwar.Thehistoryofhumanrights’victoryoverhumanrightsabusestellsus:aggressivewarsarethemostseriousviolationsofhumanrights.Wemustprotectpeople’srighttopeaceforeverycountryintheworld.Inordertoavoidviolationsofhumanrightsbywaronceagain,wemustsafeguardtheinternationalpostwarorderandpreventtherevivaloffascism,whoseessencesarecontemptforandtrampleonhumanrights.Thereforewehavetorespectandprotecthumanrightsanddefendboththecollectiverightsofeverynationandtheindividualrightsofeverypersonintheworld.

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