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简介：Inthepresentpaper,theauthorsreviewrecentsituationsofdisordersofthedigestivesystemanditsrelatedresearchprogresses.Inclinicalpractice,Neiguan(PC6)isusuallyselectedasoneofthemainintra-gastricexamination,cesareansection,etc.ConcerningexperimentalindicatedthatNeiguan(PC6)isanimportantandeffectiveacupointfortreatmentofgastrointestinaldisordersinclinic.StimulationofNeiguan(PC6)inducedfavorableregulationofboththeperipheralnervoussystemandcentralnervoussystem,andchangesofthegastrointestinalhormonesecretionmaycontributetoitseffectsintreatingvariousdisorders.

简介：RecentlytheresearchteamoftheStateKeyEngineeringLaboratoryforManufacturingOlefinsfromMethanolheadedbyAcademicianLiuZhongminandResearchFellowZhuWenliangattheCASDalianInstituteofChemicalPhysicshasmadenewprogressintheproductionofaromaticsviacouplingofmethanolwithCO.

简介：Objective:Ourgrouphaspreviouslyobservedthatinpatientswithsmall-celllungcancers(SCLCs),theexpressionofatumorantigen,gliomabigpotassium(gBK)ionchannel,ishigheratthetimeofdeaththanwhenthecancerisfirsttreatedbysurgicalresection.Thisstudyaimedtodeterminewhetherthisdichotomywascommoninotherpotentiallungtumorantigensbyexaminingthesamepatientsamplesusingourmoreextensiveprofileanalysisoftumor-antigenprecursorprotein(TAPP).WethentestedthehypothesisthattherapeuticinterventionmayinadvertentlycausethisincreasedgBKproduction.Methods:SCLCsamples(eightsurgicalresectionsandthreeautopsysamples)andthreecontrollungswereexaminedbyquantitativereal-timepolymerasechainreactionfor42potentialTAPPsthatrepresentpotentialT-cell-mediatedimmunologicaltargets.Results:Twenty-twoTAPPmRNAsdisplayedthesameprofileasgBK,i.e.,moremRNAswereexpressedatautopsythanintheirsurgicalcounterparts.B-cyclinandmousedoubleminute2,humanhomologofP53-bindingproteinwereelevatedinbothautopsyandsurgicalspecimensabovethenormal-lungcontrols.WhenHTB119cellswereincubatedwithdoxorubicin,gBKwasstronglyinduced,asconfirmedbyintracellularflowcytometrywithagBK-specificantibody.Conclusion:Ourfindingssuggestedthatmoreimmunologicaltargetsbecameavailableasthetumorrespondedtochemotherapyandproceededtowarditsterminalstages.

简介：Overthepastdecade,nineseparategenetherapyclinicaltrialsforadvancedParkinson’sdisease(PD)havebeenlaunchedandcompleted,involvingthedosingofnearly12-dozenPDvolunteerswhoincurredsignificantriskstohopefullyreducesymptomsand

简介：RecentexperimentalresultsofHL-1MtokamakandprogressofHL-2Aprojectarepresented.Strongfishboneinstabilitywasobservedduringoff-axisECRH.ThisisfirstobservationofthefishboneinstabilitypurelydrivenbyenergeticelectronsproducedbyECRH.TheMBIwasfirstproposedanddemonstratedonHL-1M.RecentlynewresultsofMBIexperimentwereobtainedbyincreasingthepressureofgas.Astair-shapedensityincrementwasobtainedwithhigh-pressuremulti-pulseMBIjustlikethedensityevolutionbehaviorduringthemultipelletinjection.Itisshown

简介：Duringthepastyear,biophysicsgroupatInstituteofModernPhysics(IMP)obtainedlotsofachievementsintheresearchofheavy-ionmutationbreedingandproductionchainofsweetsorghum.Infundamentalresearchfield,amutantpopulationofArabidopsisthalianainducedbycarbonionbeamradiationwasestablishedinM2generation.Thetotalmutationratewas4.77%.Amutantmarked197#,whichhadfrostbite-like,palegreen,wrinkledandunevenleavesanddisplayedloosebractsandlatematuration,wasobtainedandreportedforthefirsttime.Generoughmappingresultsdemonstratedthatthereweretwomutationsitesinthe1stand4thchromosomeof197#mutant,indicatingheavyionradiationmightinducemorecomplicatedmutationsbeyondourcurrentrecognition.Thewholegenomeresequencingofthismutantisstillinprogress.Inaddition,high-yieldstrainsofmicrobeswhichhavepotentialvalueforcommercialapplication,suchasCorynebacteriumglutamicumandLacbobacillusthermophiles,werescreenedusingheavy-ionmutationtechnique.

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简介：Prostatecancergene3(PCA3,alsoknownasDD3)isanewbiomarkerthatcouldimprovetheaccuracyofprostatecancerdiagnosis.Itisagreatbiomarkerwithfairlyhighspecificityandsensitivity.Theincidenceofprostatecancerisrisingsteadilyinmostcountries.Thecommonlyusedprostate-specificantigen(PSA)testoncegavepeoplehopeforearlydiagnosisofprostatecancer.However,thelowspecificityofthePSAtesthasresultedinalargenumberofunnecessarybiopsiesandovertreatment.Duringthepastdecade,manynewprostatecancerbiomarkershavebeenfound.Amongthese,PCA3isthemostpromising.Duetoitsgreatperformanceindistinguishingprostatecancerfromotherprostateconditions,PCA3couldlikelybeappliedforearlydiagnosisofprostatecancer,patientfollow-up,prognosisprediction,andtargetedtherapy.Afteryearsofresearch,wehaveobtainedsomeknowledgeaboutthesequenceofPCA3gene.WehavealsodeterminedtherelationshipbetweenPCA3andtheproliferationofprostatecancercellsandlearnedsomeinformationabouthowPCA3affectstumor-relatedgenesandproteins.APCA3scorehasbeencreated,andithasbeenusedinavarietyofstudies.SomeresearchershaveevenappliedPCA3totargetedtherapyandobtainedagoodeffectinvitro.Thisreviewdescribesthecurrentstateofresearch,andexploresthefutureprospectsforPCA3.更多还原

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简介：Theperi-urbanizationareaasakindofrural-urbaninterfaceischangingrapidly,inphysical,economic,andsocialterms.Thelandusepatterninsuchareaisshiftingawayfromtheassumptionsofmainstreamparadigmstonewconceptuallandscapes,whichleadstoaseriesofproblemsoneconomicdevelopmentandsocialstabilization.Therearemanyresearchesonnon-agriculturalland-useinperi-urbanizationarea.Inthispaperbothinternationalanddomesticresearchliteratureisreviewedbydividingsixparts.Thefirstpartintroducestheconceptionofperi-ur-banizationareaanditsdriverfactors.ThenInthesecondandthethirdpart,thepaperexpatiatesontheprogressinthenon-agriculturalland-useinperi-urbanareaonland-usepattern,evolution,characteristics,problems,etc.Theforthpartfocusesonthereasonsthatcausetheland-useproblemsintheresearcharea,whilethefifthpartreviewstheintegratingwaysofnon-agriculturalland-use.Finally,recommendationsforfurtherstudyaredrawwithspecificreferencetothecurrentandfuturepositionofnon-agriculturalland-usestudyinperi-urbanarea.

简介：Inthepasttwentyyears,theproportionofcoalinprimary-energyconsumptioninChinaisgenerallybetween71.3%and76.5%.Theoutputofcoalwas1.374billiontonsin19%,and1.21tonsin1998,whichrankedfirstintheworld.NowcoalisminedmainlywithmechanizationinChina,whichisplannedtoreach80%inmajorState-ownedcoalminesin2000accordingtotheplanningofthegovernment(Lietal.,1998;TangDejin,1998).ComparedwiththeUSAandAustralia,Chinahasmorecomplexcoalgeologicalstructures.Basedonhigh-resolutionseismictechniqueincoalexploration,anewseismictechniquewithhigh-precisionandhigh-resolution(2-Dand3-D)hasbeendevelopedforthepurposeofdetectingsmallgeologicalstructuresincoalmineconstructionandproductiontomeettheneedsoflarge-scalepopularizationofmechanizedcoalmininginChina.Thetechniqueislowincostandrequiresarelativelyshortperiodofexploration,withhighprecisionandwide-rangeapplications.Inthemiddleoft

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