简介:Microarraytechnologycanbeemployedtoquantitativelymeasuretheexpressionofthousandsofgenesinasingleexperiment.Ithasbecomeoneofthemaintoolsforglobalgeneexpressionanalysisinmolecularbiologyresearchinrecentyears.Thelargeamountofexpressiondatageneratedbythistechnologymakesthestudyofcertaincomplexbiologicalproblemspossible,andmachinelearningmethodsareexpectedtoplayacrucialroleintheanalysisprocess.Inthispaper,wepresentourresultsfromintegratingtheself-organizingmap(SOM)andthesupportvectormachine(SVM)fortheanalysisofthevariousfunctionsofzebrafishgenesbasedontheirexpression.Themostdistinctivecharacteristicofourzebrafishgeneexpressionisthatthenumberofsamplesofdifferentclassesisimbalanced.WediscusshowSOMcanbeusedasadata-filteringtooltoimprovetheclassificationperformanceoftheSVMonthisdataset.
简介:计算机图形和人的计算机相互作用的许多最近的应用程序作为输入设备采用了颜色照相机和深度照相机。因此,拿不同颜色和深度的硬件的两种类型的有效刻度输入被要求。我们的途径移开在明确地象在深度和颜色照相机之间的转变一样解决照相机intrinsics的以前的方法使用非线性的优化的数字困难。混合参数的一个矩阵被介绍线性化我们的优化。混合参数从深度提供转变参量的空格(深度照相机图象)到一种颜色由从深度照相机联合深度照相机和旋转转变的内在的参数到颜色的参量的空格(颜色照相机图象)照相机。旋转转变和内在的参数能明确地在标准QRfactorisation的帮助下从我们的混合参数被计算。我们与地面真相深度信息被微软Kinect捕获的综合数据和真实世界的数据测试我们的算法。当由于使用混合参数的优点花少得多计算时间(Herreras方法的1/50和Raposos方法的1/10)时,实验证明我们的途径能向刻度的可比较的精确性提供最先进的算法。
简介:Inthispaper,aKELM-basedensemblelearningapproach,integratingGrangercausalitytest,greyrelationalanalysisandKELM(KernelExtremeLearningMachine),isproposedfortheexchangerateforecasting.Thestudyusesasetofsixteenmacroeconomicvariablesincluding,import,export,foreignexchangereserves,etc.Furthermore,theselectedvariablesarerankedandthenthreeofthem,whichhavethehighestdegreesofrelevancewiththeexchangerate,arefilteredoutbyGrangercausalitytestandthegreyrelationalanalysis,torepresentthedomesticsituation.Then,basedonthedomesticsituation,KELMisutilizedformedium-termRMB/USDforecasting.TheempiricalresultsshowthattheproposedKELM-basedensemblelearningapproachoutperformsallotherbenchmarkmodelsindifferentforecastinghorizons,whichimpliesthattheKELM-basedensemblelearningapproachisapowerfullearningapproachforexchangeratesforecasting.
简介:Inrecentyears,therearemanycrimesrelateddrugfraudoccuringinChinaandmanyexpertsthinkthatthemaincauseisthatChinaFoodandDrugAdministration(CFDA)adoptsannouncedinspection(AI).Inordertocircumventthisdifficulty,CFDAhasexploitedunannouncedinspection(UI)since2014.Inthispaper,theauthorsstudytheproblemofwhichoneperformsbetter,AIorUI.Specifically,theauthorsconsiderasupervisor,whichdecidestheinspectionapproach,inspectionstrengthandpunishmenttoforcethefirmtoputself-inspectionefforttomeettherequirementsofGoodManufacturingPractice,andafirm,whichproducesadruganddecidesitsself-inspectioneffort.Theauthorsusegametheorytomodelthisproblem,characterizetheequilibriumpoliciesunderAI,andcomparetheeffectsofthetwoapproachesonpreventingdrugfraudundercompleteandincompleteinformation.Theresultsshowthatunderthecompleteinformation,UIperformsbetterifthefirm'stechnicallevelandtheinspectioncostarelowandAIperformsbetterotherwise.Whenthesupervisordoesn'tknowthefirm'stechnicallevel,ifthelowtechnicallevelishigh,AIperformsbetter.Otherwise,UIperformsbetteriftheinspectioncostislowandAIperformsbetteriftheinspectioncostishigh.
简介:Whilegametheoretictoolshavebeenwidelyappliedtonuclearproliferationanddisarmamentissues,traditionaldecisionanalysisassumesthatdecisionmakers,options,andpreferencesarefixed.Adramatheoreticapproachisusedtoovercometheselimitingassumptions:DramaTheory(DT)Ⅱallowsgloballeadersandnationalsecuritypolicymakerstoengageinarational-emotionalprocessofre-defininginternationalsecuritynegotiations(andtheir'positions'inthem)untilagreementonasatisfactorynuclearnon-proliferationresolutionisreached.The2009nuclearenergynegotiationsbetweenIranandworldpowersaremodeledwithDTⅡandtheConfrontationManagerTMDecisionSupportSystem.Byadjustingstrategyandderivingtransformativesecuritypolicy,itisshownhowinternationalsecuritycanbeachievedbypromotingnuclearnon-proliferationandresolvingstrategicconflict.
简介:IntegratedApproachtoFamilyPlanning:MinisterPengPeiyunStressesTransitionsⅠ.WhatistheIntegratedApproach?Intheearly1990s,familyp...
简介:AbstractAdvances in imaging for preoperative localization have propelled the widespread adoption of minimally invasive/focused parathyroidectomy in primary hyperparathyroidism. Though it is performed through a relatively small incision, studies have shown that the presence of a neck scar increases attentional bias towards the neck resulting in compromised quality of life. Transoral endoscopic parathyroidectomy vestibular approach (TOEPVA) eliminates a neck scar. While indications for TOEPVA are the same as that of minimally invasive open parathyroidectomy, confident preoperative localization of the parathyroid with a surgeon performed ultrasound along with concordant localization with SPECT CT is an essential prerequisite before offering patients this approach for parathyroidectomy. Early data has demonstrated the feasibility and safety of this approach.
简介:Inourpreviouswork,aplasmaapproachforsingleattosecondpulse(AP)generationwasproposed.Afew-cyclerelativisticcircularlypolarizedlaserpulsewillinduceasingledrasticoscillationofplasmaboundary,fromwhichhigh-orderharmonicsandfurthermoreanultra-intensesingleAPcanbegeneratednaturallyafteritisreflected.Analyticalmodelandsimulationsbothdemonstratethattheprocessismostlyefficientasthepulsedurationisclosetotheplasmarespondingtime.Theeffectsofplasmadensityrampareanalyzedhere,suggestingthattheproposalisstillquiteefficientwithappropriatedensitygradientintheramp.Atlast,acombinedapproachisemployedtoobtainsingleAPwith30fsincidentlaser.Therelativelylarge-durationpulseisfirstlyshortenedbyadensitydroppingthinfoil,andthenreflectedfromanoverdenseplasmatarget.One-dimensionalsimulationshowsthata600assinglelightpulseisgeneratedwithpeakintensityof3×1020W/cm2.
简介:在这篇文章,有关表面和界面的紧张的试验性的大小跟随简短介绍,为为二进制代码计算表面紧张和表面分离的方法,第三,并且多部件高温度基于蝇绳融化“soriginal处理并且在可得到的物理性质和热力学的数据上,特别体积阶段和表面阶段对温度的免费精力从热力学的数据库获得了使用相图(CALPHAD)的计算的excessGibbs来临,与到模型参数β的特殊注意,被描述了。另外,几何模型能被扩大预言表面紧张多亚二进制代码系统的从那些的部件系统。在nanoparticle系统的二元合金的Forillustration,一些计算例子,包括的Pb免费的焊接系统和phase-diagramevaluation被给。根据紧张ofhigh温度融化的表面,在象moltens一样的液体合金和熔融的炉渣之间的界面的紧张落后,熔融的物质能用Girifalco好的方程是计算的。修正在Nishizawa被建议“为在液体金属(A)/ceramics(MX)的界面的紧张的评价的s模型系统以便计算能基于潜水艇晶格模型和热力学的数据被执行,没有故意在高温度区分MX的阶段。最后,为预言在thehigh温度多部件之间的界面的紧张的一个近似表达式的推导融化,雇用贝克尔“与蝇绳一起的s模型”sequation和简单系统的界面的紧张数据被描述,并且有关焦性没食子酸的一些例子冶金系统为更好理解被给。
简介:QuantumMolecularDynamicsApproachforLowEnergyHeavyIonReactions¥WeiZhiyongandZhuYongtaiFragmentationintheheavyionreact...
简介:OurStudentsOurstudentsarescholarsselectedbytheChinesegovernmentforfurtherstudyintheU.K.whocometoChengdufor3-4monthsintensiveEnglishlanguagetraining.AttheendofthetrainingcoursetheyhavetotaketheIELTStest.OurtaskistoequipthemforstudyinBritain,andtopreparethemforthetestwhichwilldecidetheirfuture.
简介:Aconstructivetheoremisestablishedforgeneralizedsynchronization(GS)relatedtoC1diffeomorphictransformationsofunidirectionallycoupleddynamicalarrays.ThetheoremprovidessomeinterpretationsabouttheunderlyingmechanismofvariousGSphenomenainnature.Asadirectapplicationofthetheorem,achaos-basedsecureInternetcommunicationschemeisproposed.Moreover,acellularneuralnetwork(CNN)ofChen'schaoticcircuitswithGSpropertyisdesignedandstudied.NumericalsimulationshowsthatthisChen'sCNNhashighsecurityandisfastandreliableforsecureInternetcommunications.