简介:【摘要】目的:分析亲水性软性角膜接触镜用于治疗大泡性角膜病变和丝状角膜炎的临床效果。方法:实验数据样本选取我院于 2018年 1月至 2019年 1月期间收治的 120例大泡性角膜病变和丝状角膜炎患者 ,并按照随机的原则等分成两组进行对比实验(实验组和对照组),实验组和对照组患者均为 60例。对照组选用传统的药物治疗方式,实验组则在对照组的药物治疗基础上佩戴 亲水性软性角膜接触镜进行治疗。在治疗1周后,对临床症状的缓解和角膜上皮创面的愈合状况进行两组间比较。结果:临床症状完全缓解比率方面实验组显著优于对照组,存在差异,具有统计意义学( P< 0.05);对比治疗 1周后的角膜上皮愈合情况,丝状角膜炎实验组状况好于对照组,存在差异,具有统计意义学( P< 0.05)。结论:选用亲水性软性角膜接触镜对大泡性角膜病变和丝状角膜炎进行治疗,能够及早缓解临床症状,减轻患者的苦楚,还能有效促进丝状角膜炎患者角膜上皮的恢复,值得在临床上推广运用。 Objective: to analyze the clinical effect of hydrophilic soft contact lens in the treatment of bullous keratopathy and filamentous keratitis. Methods: 120 patients with bullous keratopathy and filamentous keratitis treated in our hospital from January 2018 to January 2019 were selected and randomly divided into two groups (experimental group and control group). There were 60 patients in the experimental group and the control group. The control group was treated with traditional drug therapy, while the experimental group was treated with hydrophilic soft corneal contact lens on the basis of drug treatment in the control group. After a week of treatment, the clinical symptoms remission and the healing of corneal epithelial wound were compared between the two groups. Results: the complete remission rate of clinical symptoms in the experimental group was significantly better than that in the control group (P < 0.05), and the corneal epithelial healing in the experimental group with filamentous keratitis was better than that in the control group (P < 0.05). Conclusion: the treatment of bullous keratopathy and filamentous keratitis with hydrophilic soft contact lens can relieve the clinical symptoms and relieve the suffering of the patients as soon as possible, and can also effectively promote the recovery of corneal epithelial cells in patients with filamentous keratitis. It should be popularized and applied in clinic. [key words] hydrophilic soft corneal contact lens; bullous keratopathy; filamentous keratitis; clinical study 【关键词】亲水性软性角膜接触镜;大泡性角膜病变;丝状角膜炎;临床研究
简介:【摘要】目的:探究大剂量维生素 C配合磷酸肌酸钠治疗小儿病毒性心肌炎效果。方法:选择 2017年 12月到 2018年 12月本院收治的小儿病毒性心肌炎患者作为研究对象,从中抽选出 80例患儿,将这 80例小儿病毒性心肌炎患者均分为对照组、观察组,一组 40例。对照组患儿给予常规治疗、观察组患儿给予大剂量维生素 C+磷酸肌酸钠进行治疗。对比两组患儿治疗前后肌酸激酶( CK)、磷酸肌酸激同工酶( CK-MB)、肌钙蛋白Ⅰ( cTnI)。结果:观察组治疗后各项指标均低于对照组: P值< 0.05。结论:对小儿病毒性心肌炎患者采用大剂量维生素 C配合磷酸肌酸钠进行治疗效果显著。
简介:【摘要】目的:就大剂量环磷酰胺联合醋酸泼尼松片对肾病综合征型紫癜性肾炎患儿症状改善及肾功能的影响进行研究分析。方法:纳入我院 2017 年 4 月至 2019 年 1 月期间收治的 肾病综合征型紫癜性肾炎患儿 122 例为研究对象,根据患儿入院就诊顺序分为研究组( 61 例)及参照组( 61 例),参照组患儿给予 醋酸泼尼松片给药,研究组患儿在此基础上联合给予 大剂量环磷酰胺给药,对两组患儿症状改善情况及肾功能进行评定比较。结果: 治疗后研究组患儿治疗总缓解率显著优于参照组( P < 0.05 );治疗后两组患者 BUN 、 Scr 等水平均显著降低( P < 0.05 ),研究组患者 BUN 、 Scr 水平均显著低于参照组( P < 0.05 )。结论:对 肾病综合征型紫癜性肾炎患儿给予 大剂量环磷酰胺联合醋酸泼尼松片给药,相较于单一 醋酸泼尼松片治疗,在改善患者临床症状体征与肾功能方面效果显著,值得采用并推广。