简介:Motiondeblurringisabasicprobleminthefieldofimageprocessingandanalysis.Thispaperproposesanewmethodofsingleimageblinddeblurringwhichcanbesignificanttokernelestimationandnon-blinddeconvolution.Experimentsshowthatthedetailsoftheimagedestroythestructureofthekernel,especiallywhentheblurkernelislarge.SoweextracttheimagestructurewithsalientedgesbythemethodbasedonRTV.Inaddition,thetraditionalmethodformotionblurkernelestimationbasedonsparsepriorsisconducivetogainasparseblurkernel.Butthesepriorsdonotensurethecontinuityofblurkernelandsometimesinducenoisyestimatedresults.ThereforeweproposethekernelrefinementmethodbasedonL0toovercometheaboveshortcomings.Intermsofnon-blinddeconvolutionweadopttheL1/L2regularizationterm.Comparedwiththetraditionalmethod,themethodbasedonL1/L2normhasbetteradaptabilitytoimagestructure,andtheconstructedenergyfunctionalcanbetterdescribethesharpimage.Forthismodel,aneffectivealgorithmispresentedbasedonalternatingminimizationalgorithm.
简介:Recentresearchshowsthattheadditionofchitosanmicrospheres(CMs)topoly(L-lactide)(PLLA)canresultinacompositescaffoldmaterialwithimprovedbiocompatibilityandmechanicalpropertiesfortissueengineeringapplications.However,researchregardingtheinfluenceofCMsonscaffolddegradationisabsentintheliterature.ThispaperpresentsastudyontheinvitrodegradationofscaffoldsmadefromPLLAwithCMs.Inthisstudy,thePLLA/CMsscaffoldswitha25%ratioofCMstoPLLAwereimmersedinphosphate-bufferedsaline(PBS)solutionat37℃for8weeks.Theinvitrodegradationofthescaffoldswasinvestigatedusingmicro-computedtomography(μCT),weightlossanalysis,Ramanspectroscopy,anddifferentialscanningcalorimetry(DSC).MicrostructurechangesduringdegradationweremonitoredusingμCT.TheμCTresultswereconsistentwiththeresultsobtainedfromRamanspectraandDSCanalysis,whichreflectedthataddingCMsintoPLLAcandecreasethedegradationratecomparedwithpurePLLAscaffolds.TheresultssuggestthatPLLA/CMsscaffolddegradationcanberegulatedandcontrolledtomeetrequirementsimposedagiventissueengineeringapplication.
简介:摘要目的探讨微量离心柱法检测甲胎蛋白异质体(AFP-L3)在肝癌预警及良恶性肝病鉴别诊断中的临床应用价值。方法使用装有耦联小扁豆凝集素(LCA)的甲胎蛋白异质体(AFP-L3)亲和吸附离心管分离原发性肝癌组、肝硬化组和慢性肝炎组共183例患者血清甲胎蛋白异质体(AFP-L3),采用郑州安图LUMO化学发光分析仪检测分离前AFP和分离后AFP(AFP-L3),计算AFP-L3占AFP总量的百分比AFP-L3(%)。结果①原发性肝癌组AFP-L3均值和阳性率明显高于肝硬化组和慢性肝炎组(P<0.001);低浓度AFP(AFP<200μg/L)原发性肝癌组AFP-L3也明显高于肝硬化组和慢性肝炎组(P<0.01)。②在原发性肝癌组中,不同浓度AFP均值和阳性率相比,差异无统计学意义(P>0.05)。结论应用新型亲和离心柱法检测甲胎蛋白异质体(AFP-L3)在肝癌与良性肝病的诊断中具有重要意义,尤其对低浓度原发性肝癌和良性肝病的鉴别诊断具有重要的临床价值。
简介:<正>当前几乎所有的现代/起亚车型中使用的2.4L排量的发动机都是一款被称为Theta的汽油发动机,该款发动机根据装车年限的不同,分为Theta2.4LⅠ代和Theta2.4LⅡ代两代机型。其中第二代机型与第一代机型的最大区别就是第二代机型使用的是双CVVT系统,而第一代机型则是单CVVT系统。第一代Theta2.4L发动机装配的车型有北京现代的御翔和进口现代雅尊TG车型。第二代Theta2.4L发动机装配的车型有进口起亚汽车2009-2013年生产的索兰托,凯尊和进口现代汽车的2010-2012年生产的新胜达,新雅尊HG车型。另外北京现代的领翔、索纳塔八代、ix35和东风悦达起亚的K5、智跑等车型也均有装配该款发动机的车型。该款发动机的正时部分包括正时链条和机