简介:烷基配糖物1并且芳基glycosides24stereospecifically高度从商业地可得到的开始的材料在46步上被综合。acetobromo的联合反应--有unprotectivedihydroxyaglycon的D葡萄糖面对钠氢氧化物面对银氧化物,或与芳香的aglycon生产了关键中介。仅仅配置glycosides在这个过程被形成。所有这些glycosides的合成第一次被报导。
简介:Anewseriesof1,3,2-oxazaborolidinecatalystssubstitutedinposition4bythe(CH3)3C(CH2)ngroup(n=2,3,4,5)weresynthesizedandappliedtotheboranereductionofprochi-ralketones.Therelationshipbetweencatalyststructureandenantioselectivitywasdiscussed.
简介:Thesecond-ordernonlinearoptical(NLO)propertiesofaseriesofbenzothiazolederivativeswerestudiedbyuseoftheZINDO-SOSmethod.Thesechromophoresareformedbyadonor-π-bridge-acceptorsystem,basedonanitrogroupconnectedwithbenzothiazoleastheacceptorandahydroxyl-functionalaminogroupasthedonor.Forthepurposeofcomparison,wealsodesignedmoleculesinwhichnitrobenzeneisanacceptor,Thecalculationresultsindicatethatbenzothiazolederivativesexhibitlargersecond-odrderpolarizabilitiesthannitrobenzenederivatives.InordertoclarifytheoriginoftheNLOresponseofthesechromophores,theirelectronpropertieswereinvestigatedaswell.Thebenzothiazolederivativesaregoodcandidatesforapplicationinelectro-opticaldeviceduetotheirhighopticalnonlinearities,goodthermalandphotonicstability.
简介:一系列新奇phthalimides对七phytopathogenic真菌在vitro为抗真菌的活动作好准备并且测试:Rhizoctoniasolani,镰刀霉oxysporumf.sp。cucumerinum欧文,Botrytiscinerea,Fulviafulva,SclerotiniasclerotiorumdeBary,Phytophthoracapsici,Botryosphaeriaberengeriama。结果证明保持6-methylpyridin-2-yl的结构的那些混合物对Phytophthoracapsici和Botrytiscinerea展出了好活动。
简介:Theoreticalconsiderationwasproposedforthefrequencyresponseofaseriespiezoelectricsensortothepropertiesofliquidandverifiedexperimentally.Thiskindofsensorhassensitiveandselectivefrequencyresponsetothepermittivityandspecificconductivityofsolutionwithexcellentstability,andwasappliedtothedeterminationofmicro-contentofwaterinorganicsolvents.Thedetectionlimitis0.01g/Lindioxane.
简介:benzothiazole衍生物的新系列被设计并且综合。最新综合的混合物对Escherichiacoli,葡萄球菌aureus和杆菌仙影拳为他们的抗菌剂活动被屏蔽。混合物6j和6o对E显示出最高的活动。coli和S。aureus。这些混合物的抗真菌的活动也对Candidaalbicans和曲霉属菌fumigatus被测试293。混合物4c,4g和6j对C展出了最高的活动。albicans。另外,混合物4a和6j对A显示了有希望的活动。fumigatus293。而混合物4a,6j和6p显示出中等活动,一样的混合物对ChromobacteriumviolaceumATCC12472为他们的察觉到antiquorum活动被检验。在里面综合混合物测试的vitrocytotoxicity对颈的癌症(Hela)和肾成纤维细胞癌症(COS-7)房间被执行线。结果显示所有测试混合物有IC50价值>50 ;对两根房间线的mol/L。分子的性质,毒性,药相似,和药获得混合物4a-c,5a,6g,h,6j,6l,6o和7c的侧面,d也被估计。
简介:Fivechiralstationaryphases(CSPs)wereusedtoseparatetheenantiomersofaseriesofO,O-diethyl(p-methyl-benzenesulfonamindo)-aryl(alkyl)-methylphosphonates.Achiralrecognitionmechanismwaspresentedtoexplaintheresolutionofthesecompounds.ResultsshowthatCSPwithstrongπ-acceptor3,5-dinitrobenzoylgroupandhighsterichindrancehasthebestresolutionabilityinchiralseparationofO,O-diethyi(p-methyl-benzenesulfonamindo)-aryl(alkyl)-methylphosphonates.WhenaCSPhasjustastrongπ-acceptor3,5-dinitrobenzoylorhighsterichindranceitdoesnothavegoodchiralresolutionability.ThechiralrecognitionismoredifficultwhentheCSPhasmorethanoneasymmetriccenter.