学科分类
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5 个结果
  • 简介:Objective:Todetecttheexistenceofimmunetoleranceinducedbygamma-rayirradiation.Methods:Peritonealcellswereharvestedfrommicesubjectedto5Gy60Cogamma-raytotalbodyirradiationat3d,7d,15dand30d,thentheircounts,morphologicalchangesandIL-12geneexpressionwereinvestigated.Results:Afterirradiation,theperitonealcellsweresharplyreduced,thecellmorphologyshiftedfromround-liketopolymorphicandfusiformwithsomeprocesses,expressionofIL-12p35wasseriouslysuppressed,whilethatofIL-12p40greatlyenhanced.Conclusion:Ourdatahighlysuggestthatthegamma-rayirradiationcouldpotentiallyinducedendriticcell(DC)commitmentandimmunetolerance.

  • 标签: 伽玛刀 免疫耐受性 树突状细胞 白细胞介素-12
  • 简介:Weevaluatedtheefficacyandsafetyofgammaknifestereotacticradiosurgery(GKSR)followedbybevacizumabcombinedwithchemotherapyin11patientswithrecurrentglioblastomamultiformewhoexperiencedtumorprogressiondespiteaggressiveinitial

  • 标签: 外科治疗 放射外科 立体定向 母细胞 伽玛刀 单抗