简介:【摘要】目的:探究将围术期饮食指导及心理护理应用于胃癌患者护理中的效果分析,其临床可应用价值。方法:将2019年1月至2020年6月作为研究时段,在该时段将我院中收入的65名胃癌患者作为研究对象,所有患者在入院后被确诊为胃癌,并选择手术方案进行治疗,按照患者入院时段分为对照组(n=32)与实验组(n=33),对照组患者选择常规护理,实验组患者则将围术期饮食指导及心理护理应用于其中,在护理完成后对患者的手术指标进行记录,分析组间差异。结果:对照组患者在手术完成后的恢复饮食时间、下床时间以及术后疼痛评分相较于对照组来说明显更优,各项数据的比差异显著(P<0.05)。结论:在对胃癌患者进行治疗时,将围术期饮食指导及心理护理应用于患者的治疗中,能够有助于改善患者的手术后恢复质量,同时还能够提高患者的总体治疗效果,对于患者的康复来说有积极的应用价值,值得推广。
简介:Thequestforneuroprotectivedrugstoslowtheprogressionofneurodegenerativediseases(NDDs),includingAlzheimer'sdisease(AD),Parkinson'sdisease(PD),andHuntington'sdisease(HD),hasbeenlargelyunrewarding.Preclinicalevidencesuggeststhatrepurposingquetiapine,lithium,valproate,fluoxetine,donepezil,andmemantineforearlyandpre-symptomaticdisease-modificationinNDDsmaybepromisingandcanspareregulatorybarriers.Theliteratureofthesepsychotropicsinearlystageandpre-symptomaticAD,PD,andHDisreviewedandpropitiousfindingsfollow.Mildcognitiveimpairment(MCI)phaseofAD:salutaryhumanrandomizedcontrolledtrialfindingsforlow-doselithiumand,inselectedpatients,donepezilawaitreplication.Pre-symptomaticAD:humanepidemiologicaldataindicatethatlithiumreducesADrisk.Animalmodelstudies(AMS)revealencouragingresultsforquetiapine,lithium,donepezil,andmemantine.EarlyPD:valproateAMSfindingsshowpromise.Pre-symptomaticPD:lithiumandvalproateAMSfindingsareencouraging.EarlyHD:uncontrolledclinicaldataindicatenon-progressionwithlithium,fluoxetine,donepezil,andmemantine.Pre-symptomaticHD:lithiumandvalproateareauspiciousinAMS.Manyotherpromisingfindingsawaitingreplication(valproateinMCI;lithium,valproate,fluoxetineinpre-symptomaticAD;lithiuminearlyPD;lithium,valproate,fluoxetineinpre-symptomaticPD;donepezilinearlyHD;lithium,fluoxetine,memantineinpre-symptomaticHD)arereviewed.Dose-andstage-dependenteffectsareconsidered.Suggestionsforsignal-enhancementinhumantrialsareprovidedforeachNDDstage.
简介:Neurotrophicfactorscompriseessentialsecretedproteinsthathaveseveralfunctionsinneuralandnon-neuraltissues,mediatingthedevelopment,survivalandmaintenanceofperipheralandcentralnervoussystem.Therefore,neurotrophicfactorissuehasbeenextensivelyinvestigatedintothecontextofneurodegenerativediseases.Alzheimer'sdiseaseandParkinson'sdiseaseshowchangesintheregulationofspecificneurotrophicfactorsandtheirreceptors,whichappeartobecriticalforneuronaldegeneration.Indeed,neurotrophicfactorspreventcelldeathindegenerativeprocessesandcanenhancethegrowthandfunctionofaffectedneuronsinthesedisorders.Basedonrecentreports,thisreviewdiscussesthemainfindingsrelatedtotheneurotrophicfactorsupport–mainlybrain-derivedneurotrophicfactorandglialcellline-derivedneurotrophicfactor–inthesurvival,proliferationandmaturationofaffectedneuronsinAlzheimer'sdiseaseandParkinson'sdiseaseaswellastheirputativeapplicationasnewtherapeuticapproachforthesediseasesmanagement.
简介:摘要目的探究急性阑尾炎患者术后要采取的护理措施和效果。方法选取2016年6月—2016年12月在我院行急性阑尾炎手术的65例患者作为研究对象,随机分为分为观察组和对照组。其中对照组32例患者采用家庭护理,医院定期给予护理指导。观察组33例患者采用阑尾炎术后专业护理,观察并对比两组患者的最终护理效果。结果观察组护理有效率为93.9%(31/33),明显高于对照组护理有效率59.4%(19/32)。观察组并发症发生率为15.2%(5/33),对照组并发症发生率为53.1%(17/32),观察组并发症发生率低于对照组。以上比较差异显著,有统计学意义(P<0.05)。结论急性阑尾炎患者的术后护理采用针对性护理的效果显著,有效提高患者的满意度,降低痛苦,具有良好的临床应用价值。