简介：PURPOSE:Weinvestigatethepatternsoffailureinthetreatmentofglioblastoma(GBM)basedonclinicaltargetvolume(CTV)marginsize,dosedeliveredtothesiteofinitialfailure,andtheuseoftemozolomideandintensity-modulatedradiotherapy(IMRT).METHODS:BetweenAugust2000andMay2010,161patientswithGBMweretreatedwithradiotherapywithorwithoutconcurrenttemozolomide.PatientsweretreatedwithCTVexpansionsthatrangedfrom5to20mmusingashrinkingfieldtechnique.PatternsoffailureandtimetoprogressionandoverallsurvivalwerecomparedbasedonCTVmargin,useoftemozolomide,anduseofIMRT.KaplanMeieranalysiswasusedtoestimatesurvivaltimes,andχtestwasusedforcomparisonofcohorts.RESULTS:Forpatientstreatedwith5-,10-,and15-to20-mmCTV,79%,77%,and86%experiencedfailuresinthe60Gyvolume,respectively.Forty-eightpercent,55%,and66%ofpatientswith5-,10-,and15-to20-mmCTVexperiencedfailuresinthe46Gyvolume,respectively.Therewasnostatisticaldifferencebetweenpatientstreatedwith5-,10-,15-to20-mmmarginswithregardto60Gyfailure(P=0.76),46Gyfailure(P=0.51),ormarginalfailure(P=0.73).Eightypercentofpatientsreceivingtemozolomideexperiencedfailuresinthe60Gyvolume.TherewasnoincreasedlikelihoodofmarginalfailuresinpatientsreceivingIMRT(P=0.97).CONCLUSIONS:Moderntreatmenttechniquesincludinguseofconcurrenttemozolmide,limitedCTVmarginsize,andIMRThavenotgreatlychangedthepatternsoffailureofGBM.

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简介：理解先于腐蚀地形的发展的地志的上下文具有在似地球形状的研究的主要关联，作为地形学是水和集体运动相关的侵蚀上的一个重要因素，并且原来的表面的知识是为确定的一个条件侵蚀的材料的体积。尽管任何重建暗示假设产生表面反映原来的地形学，过去的工作被线性插值方法统治了，不能在输入的变化的范围外面没有数据或值在区域产生弄弯的表面。尽管有这些限制，确认的不可能导致了表面representativity的假设从来没被质问。

简介：Oneofthemainrequirementsofcognitiveradiosystemsistheabilitytodetectthepresenceoftheprimaryuserwithfastspeedandpreciseaccuracy.Toachievethat,apossibletwo-stagespectrumsensingschemeissuggestedinthispaper.Morespecifically,afastspectrumsensingalgorithmbasedontheenergydetectionisintroducedfocusingonthecoarsedetection.Acomplementaryfinespectrumsensingalgorithmadoptsone-ordercyclostationarypropertiesofprimaryuser'ssignalsintimedomain.Sincetheone-orderfeaturedetectionisperformedintimedomain,thereal-timeoperationandlow-computationalcomplexitycanbeachieved.Also,itdrasticallyreduceshardwareburdensandpowerconsumptionasopposedtotwo-orderfeaturedetection.Thesensingperformanceoftheproposedmethodisstudiedandtheanalyticalperformanceresultsaregiven.Theresultsindicatethatbetterperformancecanbeachievedinproposedtwo-stagesensingdetectioncomparedtotheconventionalenergydetector.

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简介：Inthisstudy,threerapidrepairtechniquesareproposedtoretrofitcircularbridgepiersthatareseverelydamagedbytheflexuralfailuremodeinmajorearthquakes.Thequasi-statictestsonthree1:2.5scaledcircularpierspecimensareconductedtoevaluatetheefficiencyoftheproposedrepairtechniques.Forthepurposeofrapidrepair,therepairprocedureforallthespecimensisconductedwithinfourdays,andthebehavioroftherepairedspecimensisevaluatedandcomparedwiththeoriginalones.Afiniteelementmodelisdevelopedtopredictthecyclicbehavioroftherepairedspecimensandthenumericalresultsarecomparedwiththetestdata.Itisfoundthatalltherepairedspecimensexhibitsimilarorlargerlateralstrengthanddeformationcapacitythantheoriginalones.Theinitiallateralstiffnessofalltherepairedspecimensislowerthanthatoftheoriginalones,whiletheyshowahigherlateralstiffnessatthelaterstageofthetest.Nonoticeabledifferenceisobservedfortheenergydissipationcapacitybetweentheoriginalandrepairedpierspecimens.Itissuggestedthattherepairtechniqueusingtheearly-strengthconcretejacketconfinedbycarbonfiberreinforcedpolymer(CFRP)sheetscanbeanoptimalmethodfortherapidrepairofseverelyearthquake-damagedcircularbridgepierswithflexuralfailuremode.

简介：在巴基斯坦的瑞斯生产是由与流行种的技术相关的许多因素的限制。关于新种的技术的可行性的研究(在公寓上的直接播种，在公寓上移植，在山脉上的直接播种，在山脉并且降落伞种上移植)在里面移植，直接湿种子的米饭在DeraIsmail被承担巴基斯坦的北方的Khanregion韦斯特边疆省在2002和2003期间。在种的技术之中，为收益形成和经济评估的最好的表演以在两年期间在公寓上移植闻名。中国降落伞种技术也在大多数参数显示出很有希望的结果。在山脉上的直接播种不能为佼佼者在在两个都收割季节期间种的公寓和降落伞上移植。调查结果结束了与在在区域被练习的所有另外的种的技术上在公寓上移植的传统的米饭一起种技术的降落伞的可行性。

简介：High-frequencystocktrendpredictionusingmachinelearnershasraisedsubstantialinterestinliterature.Nevertheless,thereisnogoldstandardtoselecttheinputsforthelearners.Thispaperinvestigatestheapproachofadaptiveinputselection(AIS)forthetrendpredictionofhigh-frequencystockindexpriceandcomparesitwiththecommonlyuseddeterministicinputsetting(DIS)approach.TheDISapproachisimplementedthroughcomputationoftechnicalindicatorvaluesondeterministicperiodparameters.TheAISapproachselectsthemostsuitableindicatorsandtheirparametersforthetime-varyingdatasetusingfeatureselectionmethods.Twostate-of-the-artmachinelearners,supportvectormachine(SVM)andartificialneuralnetwork(ANN),areadoptedaslearningmodels.AccuracyandF-measureofSVMandANNmodelswithboththeapproachesarecomputedbasedonthehigh-frequencydataofCSI300index.TheresultssuggestthattheAISapproachusingt-statistics,informationgainandROCmethodscanachievebetterpredictionperformancethantheDISapproach.Also,theinvestmentperformanceevaluationshowsthattheAISapproachwiththesamethreefeatureselectionmethodsprovidessignificantlyhigherreturnsthantheDISapproach.

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简介：把方法基于回响，粘滞0.2-2.0kg/m3的吸收沉积和玻璃祷告混浊的海水被测量。测量结果与用粒子尺寸分布技术的预言结果更一致而不是使用平均粒子半径技术，这被显示出。由预言的比较，用粒子的结果用平均粒子半径技术与那缩放分布技术，差异是2.3-2.6dB，这被观察为沉积的1.0kg/m3的每100米在试验性的频率的范围以内的混浊的海水。粒子尺寸分布应该在预言被考虑，这被建议粘滞沿海的混浊的水里的吸收。

简介：在三角形的横断面隧道和一致稳定的流动的假设下面，最小的生态的在里面溪流流动要求(MEIFR)的一个分析答案被推出。基于分析答案，弄湿的周界方法的不确定性被在在弄湿的周界，P和分泌物之间的关系曲线上为临界点的决心比较二种技术分析，Q。这清楚地被显示出MEIFR的结果基于弯曲技术(相应于最大的弯曲)并且斜坡技术(倾斜是1)是显著地不同的。在P-Q曲线上，有最大的弯曲的临界点的斜坡是0.39，MEIFR与斜坡阀值的变化显著地变化。这显示如果斜坡阀值的某个价值不为斜坡技术是可得到的，弯曲技术可以是一种更好的选择。由在西方的线路South-to-North的输的河里使用分析解决方案ofMEIFR，水在中国转移工程，经由弯曲技术的theMEIFR价值是多年一般水准annual分泌物的2.5%-23.7%，当那为斜坡技术是11%-105.7%时。一般结论将为各种剖面图依靠更多的详细研究。

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简介：Thelocalthermalconductivityofpolycrystallinealuminumnitride(AlN)ceramicsismeasuredandimagedbyusingascanningthermalmicroscope(SThM)andcomplementaryscanningelectronmicroscope(SEM)basedtechniquesatroomtemperature.ThequantitativethermalconductivityfortheAlNsampleisgainedbyusingaSThMwithaspatialresolutionofsub-micrometerscalethroughusingthe3ωmethod.Athermalconductivityof308W/m·Kwithingrainscorrespondingtothatofhigh-puritysinglecrystalAlNisobtained.Theslightdifferencesinthermalconductionbetweentheadjacentgrainsarefoundtoresultfromcrystallographicmisorientations,asdemonstratedintheelectronbackscattereddiffraction.Amuchlowerthermalconductivityatthegrainboundaryisduetoimpuritiesanddefectsenrichedinthesesites,asindicatedbyenergydispersiveX-rayspectroscopy.

简介：Theabilitytomodulatethefutureliverremnant(FLR)isakeycomponentofmodernoncologichepatobiliarysurgerypracticeandhasextendedsurgicalcandidacyforpatientswhomayhavebeenpreviouslythoughtunabletosurviveliverresection.MultipletechniqueshavebeendevelopedtoaugmenttheFLRincludingportalveinembolization(PVE),associatingliverpartitionandportalveinligation(ALPPS),andtherecentlyreportedtranshepaticlivervenousdeprivation(LVD).PVEisawell-establishedmeanstoimprovethesafetyofliverresectionbyredirectingbloodflowtotheFLRinanefforttoselectivelyhypertrophyandultimatelyimprovefunctionalreserveoftheFLR.ThisarticlediscussesthecurrentpracticeofPVEwithfocusonsummarizingthelargenumberofpublishedreportsfromwhichoutcomesbasedpracticeshavebeendeveloped.BothtechnicalaspectsofPVEincludingvolumetry,approaches,andembolizationagents;andclinicalaspectsofPVEincludingdatasupportingindications,anditsroleinconjunctionwithchemotherapyandtransarterialembolizationwillbehighlighted.PVEremainsanimportantaspectofoncologiccare;inlargepartduetothesubstantialfoundationofinformationavailabledemonstratingitsclearclinicalbenefitforhepaticresectioncandidateswithsmallanticipatedFLRs.

简介：TheLudaoLakewithanareaof0.86km2and50%watersurfaceratio,wastakenasanexampletostudytheeco-hydraulicstechniquesforpreventinglakeeutrophication.Besidesexternalwaterinflowandoutflow,thetermrelatedtointernallocalflowcirculationwasaddedinthecontinuityequationoftwo-dimensionalhorizontalhydrodynamicmodel,andfurtherthehydrodynamicmodelwascalibratedbythescenarioofnowaterexchange.Thevelocityof0.2m/swassuggestedtobethecriticalvelocityofcontrollingalgalbloom.Toachievethecriticalvelocityinthewholelake,threefactorswereanalyzed,whicharewind,artificialexternalinflowaugmentationandinternallocalflowdisturbancebypumpcirculation.Itisfoundthattheroleofwindcanbedisregarded.Fortheeco-hydraulicstechniqueofexternallakewaterinflowaugmentation,thewaterflowingrouteshouldbefirstlyoptimized,further,thelakeinflowhasacriticalvalueunderspecifiedwaterlevelduetothenarrowinlets,sothewholelakeisdifficulttoreachthecriticalvelocitytopreventalgalbloom,andacombinationofexternalinflowaugmentationandinternallocalflowingdisturbanceshouldbeconsidered.Simulationresultsshowthatthecombinationofexternalwaterinflowaugmentationandinternallocalflowdisturbancerequireslesseco-flowtoachievetheglobalcriticalvelocitythanthesoleinternallocalflowdisturbance,fortheLudaoLake,theformerrequirestotaleco-flowof25m3/s,whichreducesby50%thanthelatterrequiringtotaleco-flowof52m3/s.

简介：１ＩｎｔｒｏｄｕｃｔｉｏｎＭｅｃｈａｎｉｃａｌＣＡＤｓｙｓｔｅｍｓｕｓｅ３Ｄｇｅｏｍｅｔｒｉｃｒｅｐｒｅｓｅｎｔａｔｉｏｎｔｏｆｏｒｍｔｈｅｇｌｏｂａｌｐｒｏｄｕｃｔｉｎｆｏｒｍａｔｉｏｎｍｏｄｅｌｆｏｒｓａｔｉｓｆｙｉｎｇｔｈｅｗｈｏｌｅｌｉｆｅ...

简介：AbstractPurpose:The majority of acute anterior shoulder dislocations are sustained during sports and wilderness activities. The management of acute dislocations in the pre-hospital setting is currently without guidelines based on the evidence. The study aims to assess the risk of acute complications in pre-hospital shoulder reduction and identify which pre-hospital reduction technique has the highest success rate in the published literature.Methods:The involved databases were Allied and Complementary Medicine, CENTRAL, CINAHL, Cochrane Database of Systematic Reviews, Embase, Europe PMC, Ovid MEDLINE®, Pedro, Proquest, Trip, and World Health Organization International Clinical Trials Registry platform. Only original research of high methodological quality was included, which was defined by the recently developed assessment tool-assessing the methodological quality of published papers (AMQPP) and investigated the management of acute anterior shoulder dislocations in the pre-hospital setting.Results:Two hundred and ninety-eight articles were identified and screened. A full text review was performed on 40 articles. Four articles published between 2015 and 2018 met the inclusion criteria. A total of 181 patients were included with the study duration ranging from 6 to 60 months. All studies reported zero immediate complication following pre-hospital reduction and there were no documented subsequent adverse events regardless of the technique used. Prompt resolution of neurological symptoms was observed following the early and successful pre-hospital reduction. First attempt success rate, when performed by skilled practitioners, ranged from 72.3% to 94.9%.Conclusion:Pre-hospital shoulder reduction appears to be a safe and feasible option when carried out with the appropriate expertise. A novel reduction technique adapted from the mountain medicine diploma course at the University of Paris North was found to have the highest first attempt reduction success rate of 94.9%. Other techniques described in the literature included Hippocratic, Stimson's, Counter-traction and external rotation with the success rates ranging from 54% to 71.7%.