简介:【摘要】目的:本研究的目的是评估片剂赋形剂的内在溶出速率对于药物溶出的影响。在这方面由于缺乏有关药物溶出速率的信息,这使得该问题成为研究人员关注的主题。方法:模拟了三种不同形状的片剂,分别为圆形、长方形、双凸形状,以制备多潘立酮片剂。使用USP溶出度仪II完成体外溶出度测试。通过计算各种溶出参数评估药物溶出速率;例如,溶出效率(DE),平均溶出速率(MDR),平均溶出时间(MDT)。结果:关于崩解时间,较大的片剂表现出更快的崩解时间。当片剂尺寸较小时,释放的药物量显着减少。另外,具有平坦或双凸几何形状的药片对DE值有明显的影响。通常,双凸片剂具有比扁平片剂更高的DE百分数。结论:不同的几何形状溶出参数存在明显差异,这在药物释放动力学中起着重要作用,这对口服快速起效具有重要作用。
简介:[摘要 ] 目的 控制灭菌包湿包的发生 ,保证灭菌包的质量。 方法 进行不同装载方法,比较湿包的发生率 。 结果 利用波浪型不锈钢活动支架隔开摆放比直接摆放装载,包与包互相挨靠的湿包率低,竖立稍向塑面倾斜比完全竖立装载湿包率低。结论 正确装载可大大减少灭菌包湿包的发生,保证灭菌包质量。
简介:[摘要 ]目的 对出疹性传染病的临床特点进行分析,并总结防控策略。方法 选取 2018年 11月 ~2019年 11月医院收治的 112例出疹性传染病患者,对其临床资料进行回顾性分析,通过体查、询问和实验室检查对病情进行诊断,在诊断后采取及时隔离和针对性治疗,观察出疹性传染病诊断结果和治疗结果。结果 经过对 112例患者的问诊、检查后,发现病毒性感染出疹 83例 (56%),细菌性感染出疹 4例 (3.57%),过敏性出疹 25例 (22.32%);患者经治疗均治愈康复,治愈率达 100%。结论 出疹性传染病种类较多,需尽早检查诊断和治疗,目前通过加强健康宣教和加强疫情监测进行预防,通过提高患者健康安全意识,保持良好的生活卫生,可有效预防出疹性传染病。
简介: [摘要 ]目的:研究Ⅲ度子宫脱垂合并阴道膨出患者应用经阴道全子宫全阴道切除术的临床疗效。方法:随机抽取 29例我院妇产科收治的Ⅲ度子宫脱垂合并阴道膨出患者,将接受经阴道全子宫全阴道切除术的患者纳入观察组( n=16),将接受经阴道全子宫切除术联合修补治疗的患者纳入对比组( n=13)。结果: 2组患者出血量差异不存在统计学意义( t=0.7260, p=0.0524),观察组患者排气时间短于对比组,差异存在统计学意义( t=13.2502, p=0.0118),住院时间短于对比组,差异存在统计学意义( t=16.2930, P=0.0259)。观察组患者并发症总发生率为 18.75%,对比组并发症总发生率为 46.15%,观察组并发症总发生率明显较对比组患者低, 2组差异存在统计学意义( x2=17.8732, p=0.0159)。结论:Ⅲ度子宫脱垂合并阴道膨出患者应用经阴道全子宮全阴道切除术可缩短患者术后恢复时间且具有更高的应用安全性。 [关键词 ]经阴道全子宫全阴道切除术 ;Ⅲ度子宫脱垂 ;阴道膨出 [Abstract] Objective: To study the clinical effect of transvaginal hysterectomy in patients with third degree uterine prolapse and vaginal prolapse. Methods: 29 patients with third degree uterine prolapse and vaginal prolapse were randomly selected. The patients who received transvaginal hysterectomy were included in the observation group (n = 16), and the patients who received transvaginal hysterectomy and repair were included in the control group (n = 13). Results: there was no significant difference in the amount of bleeding between the two groups (t = 0.7260, P = 0.0524), the exhaust time of the observation group was shorter than that of the control group, the difference was statistically significant (t = 13.2502, P = 0.0118), the length of stay was shorter than that of the control group, and the difference was statistically significant (t = 16.2930, P = 0.0259). The total incidence of complications was 18.75% in the observation group and 46.15% in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group. The difference between the two groups was statistically significant (x2 = 17.8732, P = 0.0159). Conclusion: transvaginal hysterectomy can shorten the recovery time of patients with third degree uterine prolapse and vaginal prolapse.
简介: [摘要 ]目的:研究Ⅲ度子宫脱垂合并阴道膨出患者应用经阴道全子宫全阴道切除术的临床疗效。方法:随机抽取 29例我院妇产科收治的Ⅲ度子宫脱垂合并阴道膨出患者,将接受经阴道全子宫全阴道切除术的患者纳入观察组( n=16),将接受经阴道全子宫切除术联合修补治疗的患者纳入对比组( n=13)。结果: 2组患者出血量差异不存在统计学意义( t=0.7260, p=0.0524),观察组患者排气时间短于对比组,差异存在统计学意义( t=13.2502, p=0.0118),住院时间短于对比组,差异存在统计学意义( t=16.2930, P=0.0259)。观察组患者并发症总发生率为 18.75%,对比组并发症总发生率为 46.15%,观察组并发症总发生率明显较对比组患者低, 2组差异存在统计学意义( x2=17.8732, p=0.0159)。结论:Ⅲ度子宫脱垂合并阴道膨出患者应用经阴道全子宮全阴道切除术可缩短患者术后恢复时间且具有更高的应用安全性。 [关键词 ]经阴道全子宫全阴道切除术 ;Ⅲ度子宫脱垂 ;阴道膨出 [Abstract] Objective: To study the clinical effect of transvaginal hysterectomy in patients with third degree uterine prolapse and vaginal prolapse. Methods: 29 patients with third degree uterine prolapse and vaginal prolapse were randomly selected. The patients who received transvaginal hysterectomy were included in the observation group (n = 16), and the patients who received transvaginal hysterectomy and repair were included in the control group (n = 13). Results: there was no significant difference in the amount of bleeding between the two groups (t = 0.7260, P = 0.0524), the exhaust time of the observation group was shorter than that of the control group, the difference was statistically significant (t = 13.2502, P = 0.0118), the length of stay was shorter than that of the control group, and the difference was statistically significant (t = 16.2930, P = 0.0259). The total incidence of complications was 18.75% in the observation group and 46.15% in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group. The difference between the two groups was statistically significant (x2 = 17.8732, P = 0.0159). Conclusion: transvaginal hysterectomy can shorten the recovery time of patients with third degree uterine prolapse and vaginal prolapse.
简介:【摘要】 目的 探讨对子宫脱垂伴阴道前后壁膨出患者采用阴式子宫切除和阴道修补术治疗的临床疗效。方法 对 2018年 1月 -2020年 1月本院妇产科收治的 100例子宫脱垂伴阴道前后壁膨出患者进行观察,将采用阴式子宫切除术、阴道修补术联合治疗的 60例患者分为研究组,将采用常规手术治疗的 40例患者分为对照组,观察两组患者的手术相关指标、总有效率及并发症发生情况。随访 2年,观察复发情况。结果 研究组平均住院时间、手术时间、术后排气时间、术中出血量、 2年内复发率、并发症均低于对照组,且总有效率明显更高,有统计学意义( P< 0.05)。结论 阴式子宫切除术、阴道修补术联合手术对子宫脱垂伴阴道前后壁膨出患者的疗效突出,创伤性小、并发症少、复发率低,在腹部不留瘢痕,缩短了患者的治疗时间。