摘要
Thisstudywasundertakentohaveabetterunderstandfortheprocessandtheunderlyingmechanismstolimitmacrophageactivationandpopulationofactivatedmacrophages.AcomprehensivekineticsofcytokineproductionwasperformedinmurineperitonealmacrophagesrecoveredfromBalb/cmiceatvarioustimeduringthecourseofanintraperitonealinjectionwiththioglycollate(TG).TheexpressionofcellsurfacemoleculessuchasMHC-Ⅰ,MHC-Ⅱ,B7-1andB7-2ofthesemacrophageswerealsodeterminedbyflowcytometry.Thepresentfindingsofourresearchsuggestedthatthepopulationofactivatedmacrophagesandtheactivationofmacrophages(includingcytokinesproductionandexpressionofcellsurfacefunctionalmolecules)werestrictlycontrolledduringinflammationprocess.Thisisoneoftheimportantmechanismstoretainthehosthomeostasis.Cellular&MolecularImmunology.2004;1(1):57-62.
出版日期
2004年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)