Inthecurrenteraofcardiovasculardisease,thediagnosisofheartfailurewithpreservedejectionfraction(HFpEF)isawell-recognizedclinicalentitythatisequallyprevalentbutdistinctlydifferentfromheartfailurewithreducedejectionfraction(HFrEF).DespitenormalEFpatientswiththisdiseasehavesimilarmorbidityandmortalityratescomparedwithHFrEF,aswellasarisingrateofhospitalizations.ThepathophysiologyofHFpEFisincompletelyunderstood.Thenumberoftherapieswithprovenefficacyatimprovinglongtermcardiovascularoutcomesislimited.Womenwithheartfailuresyndromes,particularlytheelderly,aremuchmorelikelytohaveaHFpEFphenotypeatthetimeoftheirdiagnosis.Thepurposeofthispaperistoreviewtheepidemiology,pathophysiology,clinicalfeatures,andcurrentmanagementstrategiesinHFpEF,especiallyasitpertainstowomen.
