简介:【摘 要】目的:了解白细胞(White Blood Cell, WBC)与C反应蛋白(C-reactive protein,CRP)检测在社区门诊患者中的临床价值。方法:于2018年6月-2020年8月本社区门诊中选择64例疑似病毒性感染患者及疑似细菌性感染患者作为实验样本,分别将其设定为A组、B组,选择同期门诊64例健康体检者设定为C组,所有受试者均进行WBC、CRP的检测,对检测结果存在的差异进行比较。结果:A组的WBC、CRP同C组行比较,数据间无统计学意义, P>0.05;B组的WBC、CRP均高于A组、C组,数据间存在统计学意义,P<0.05。结论:CRP、WBC在社区门诊联合检测,在临床上具有早期判断、识别感染的价值,值得借鉴和采纳。
简介:Wehavepreviouslydemonstratedtheabilityofmalariaparasitestointerferewithspecificimmuneresponses.CD4Tcellsspecifictoparasiteantigens,butnotCD4Tcellsspecifictoanirrelevantantigen,ovalbumin(OVA),aredeletedviaapoptosisduringmalariainfection.Itisofinterest,therefore,toinvestigatetheimmuneresponsesthatdevelopedfollowingvaccinationwiththe19kDacarboxylterminusofthemerozoitesurfaceprotein1(MSP119)inmicethathadpreviouslyexperiencedmalariainfection.Inthisstudy,pre-exposureofmicetoPlasmodiumyoeliielicitednativeanti-MSP119antibodyresponses,whichcouldbeboostedbyvaccinationwithrecombinantMSP119,Likewise,infectionofMSP119-primedmicewithPlasmodiumyoelii(P.yoelii)ledtoanincreaseofanti-MSP119antibodies.MSP119vaccinationofmalariapreexposedmiceorimmunizationbyinfection/cureofMSP119-primedmiceenabledthemicetosurvivechallengeinfection,withtheformergrouphavingslightlylowerparasitaemia.Thedatasuggestthatexposuretomalariainfectionprimesanaturalimmuneresponsewhichcanbeboostedbyvaccination.Thisinformationisrelevanttothedevelopmentofavaccineforuseinindividualslivinginmalaria-endemicareas.
简介:【摘要】目的:探讨血清铁蛋白与红细胞参数在孕产妇缺铁性贫血中的临床应用价值。方法:抽取本院2018年4月-2019年6月时段内收治的缺铁性贫血孕产妇共600例,纳入研究组;再抽取健康体检孕产妇600例,纳入对照组。均施行血清铁蛋白、红细胞参数水平测定,比较各指标对应关系。结果:①对照组红细胞参数均较优于研究组,数据比较有意义(P<0.05)。②和对照组相比,缺铁性贫血孕产妇血清铁蛋白水平均有所下降,且随着贫血程度的加重,血清铁蛋白水平越低,数据比较有意义(P<0.05)。结论:针对缺铁性贫血孕产妇,血清铁蛋白、红细胞参数不仅可起到预期诊断效果,还可精准把控缺铁性贫血程度,为后续治疗提供依据。
简介:Toinvestigatethematernal-infantileinfectionwithhumanparvovirusB19,theIgGandIgMantibodiesagainsthumanparvovirusandtheB19-DNAinserumandperipheralbloodmononuclearcells(PBMC)ofpregnantwomenaswellastheserumIgMantibodyagainstB19andtheB19-DNAinserumandcordbloodnucleatedcells(CBNC)ofnewbornsweredeterminedbyELISAandnestedPCRrespectively.ItwasfoundthatthepositiverateoftheIgGantibodyagainsthumanparvovirusB19inseraof92pregnantwomenwas38.04%(35/92),andthatoftheIgMantibodyin720pregnantwomenwas9.03%(65/720).However,theIgMantibodyagainsthumanparvovirasB19wasnegativeinthecordbloodseraof95newborns.AstothehumanparvovirasB19DNA,noneof720pregnantwomenand95newbornswasprovedtobepositiveintheirsera,Nevertheless,thepositiverateoftheparvovirasB19DNAinPBMCwas3.06%(3/98)in98pregnantwomenand1.12%(1/89)inCBNCof89newborns.ItisconcludedthatthehistoryofinfectionwithhumanparvovirasB19existsincertainpregnantwomenwithasmallpercentageofpregnantwomeninfectedwithrecentoracuteinfectionsofB19virus.ThedetectionratesoftheB19viralDNAinPBMCofpregnantwomenandCBNCofnewbornswerehigherthanthoseinsera,indicatingthattheriskforverticaltransmissionisverylow.
简介:摘要:目的 探讨重症监护病房(ICU)患者红细胞(RBC)输注后红细胞分布宽度(RDW)的变化。方法 选取我院2018年1月~2020年4月ICU输注红细胞患者157例,根据患者输血前红细胞平均体积(MCV)异常情况分为MCV异常组(n=78)与MCV正常组(n=79),比较两组输血前、输血后0、12、24、48h的RDW值,并计算RDW变化情况。结果 两组输血后RDW值均升高,于输血后24h达到最高值,RDW变化值最大,输血后48h保持保持较高水平;MCV异常组RDW最大变化值大于MCV正常组,差异有统计学意义(P