简介: 【摘 要】目的:探究他克莫司与环磷酰胺治疗狼疮性肾炎的的效果和用药不良反应率。方法:纳入观察对象 40例(均确诊为狼疮性肾炎)进行实验研究,研究时间从 2015年 3月直至 2019年 5月。采用随机分组法,将观察对象分为甲乙两组,甲组 20例患儿使用他克莫司治疗,乙组 20例患儿采取环磷酰胺治疗。观察对比两组患儿治疗效果、不良反应发生情况。结果:甲组中 1例患儿疗效不明显,另外 19例均有改善,总有效率 95%;乙组中 5例疗效不明显, 1例病情恶化,另外 14例病情改善,总有效率 70%,两组间进行比较后得到 P<0.05。治疗后随访观察到,甲组患儿 1例出现尿痛的不良反应,乙组中有 6例,两组不良反应发生率的差异显著( P<0.05)。结论:狼疮性肾炎患儿在治疗过程中可应用他克莫司与环磷酰胺进行治疗,对比发现,他克莫司可以明显提升治疗的有效率,并且控制了患儿不良反应的出现,治疗安全性得到保障,临床应用效果理想,值得推广。 【关键词】他克莫司 ;环磷酰胺 ;狼疮性肾炎 ;效果 ;不良反应率 [Abstract] Objective: To explore the effect and adverse reaction rate of tacrolimus and cyclophosphamide in the treatment of lupus nephritis. Methods: 40 patients (all diagnosed as lupus nephritis) were included in the experimental study. The study period was from March 2015 to may 2019. The observation objects were randomly divided into two groups, group A (20 cases) was treated with tacrolimus, and group B (20 cases) was treated with cyclophosphamide. The treatment effect and adverse reactions of the two groups were observed and compared. Results: in group A, the curative effect of 1 case was not obvious, the other 19 cases were improved, the total effective rate was 95%; in group B, the curative effect was not obvious in 5 cases, 1 case was deteriorated, the other 14 cases were improved, the total effective rate was 70%, the comparison between the two groups showed that P < 0.05. After treatment, 1 case of adverse reactions occurred in group A and 6 cases in group B. There was a significant difference in the incidence of adverse reactions between the two groups (P < 0.05). Conclusion: tacrolimus and cyclophosphamide can be used in the treatment of children with lupus nephritis. Compared with cyclophosphamide, tacrolimus can significantly improve the efficiency of treatment, and control the occurrence of adverse reactions in children. The safety of treatment is guaranteed and the clinical application effect is ideal, which is worthy of promotion.
简介: 摘要:目的 针对急性脑梗塞住院患者展开临床护理研究,了解舒适护理的运用效果。方法 选取我院近 2年内收治的此类患者共 60例,将其随机分为对照组及观察组。对照组采用常规护理模式,观察组采用舒适护理模式。对比两种护理模式在预后效果上的差异性。结果 采用舒适护理的观察组中未出现并发症情况,护理总有效率达到了 100%;而采用常规护理的对照组有 3例出现并发症或发病情况,护理总有效率仅为 90%。两组患者在护理效果上呈显著性差异( P<0.05)。结论 舒适护理能够针对患者住院期间可能出现的不良反应或并发症达到干预效果,提升预后有效性。 关键词:急性脑梗塞;预后;舒适护理 Abstract: objective to carry out clinical nursing research on hospitalized patients with acute cerebral infarction and understand the application effect of comfortable nursing. Methods 60 cases of such patients in our hospital in recent 2 years were randomly divided into control group and observation group. The control group was given conventional nursing mode, and the observation group was given comfortable nursing mode. To compare the difference of the two nursing modes in the prognosis. Results there were no complications in the observation group with comfortable nursing, and the total effective rate of nursing was 100%; while in the control group, there were 3 cases of complications or morbidity in the control group, and the total effective rate of nursing was only 90%. There was significant difference in nursing effect between the two groups (P < 0.05). Conclusion comfortable nursing can achieve the intervention effect for the possible adverse reactions or complications during hospitalization, and improve the effectiveness of prognosis.
简介: 【摘要】 目的 观察银杏达莫联合阿司匹林共同治疗急性脑梗的临床治疗效果。方法 急性脑梗死的患者 120 例, 随机分成对照组 60 例和治疗组 60 例, 对照组患者单独采用阿司匹林治疗, 治疗组患者在对照组患者的治疗基础上联合银杏达莫共同治疗, 观察两组患者治疗效果。结果 治疗组患者的治疗有效率 93.33% 明显高于对照组患者 80.00% , 差异有统计学意义( P<0.05 ), 治疗组患者不良反应的发生率 6.67% 明显低于对照组患者 26.67% , 差异有统计学意义( P<0.05 )。结论 采用银杏达莫联合阿司匹林共同治疗急性脑梗, 效果明显, 不良反应发生率低, 受到患者及临床医生的认可, 具有较高的临床应用价值。 【关键词】 银杏达莫;阿司匹林;急性脑梗;临床治疗效果 [Abstract] Objective To observe the clinical effect of gingko and aspirin in the treatment of acute cerebral infarction. Methods 120 patients with acute cerebral infarction were randomly divided into control group (60 cases) and treatment group (60 cases). Results the effective rate of 93.33% in the treatment group was significantly higher than 80.00% in the control group, the difference was statistically significant (P < 0.05), the incidence of adverse reactions in the treatment group was 6.67% significantly lower than 26.67% in the control group, the difference was statistically significant (P < 0.05). Conclusion gingko Damo combined with aspirin in the treatment of acute cerebral infarction has obvious effect and low incidence of adverse reactions. It is recognized by patients and clinicians and has high clinical application value.
简介: 摘要:目的:急性肠炎发病原因、临床症状以及保守治疗优质护理措施进行分析,对产生的临床效果进行研究。方法:选择本院2018年8月至2019年4月期间,在院住院治疗的88例急性肠炎患者为研究对象,对这88例患者实施保守治疗,依据患者的性别、年龄、病症情况以及选择治疗意愿的不同,随机分为两个护理小组,优质组:44例,在治疗中,采用一般护理的基础上,加入了优质护理干预;对照组:44例,在治疗中仅采用一般护理干预。经过阶段性治疗护理后,对两个组别患者的临床效果、焦虑、抑郁评分以及护理满意率进行调查与分析。结果:优质组:44例,治愈38例,有效5例,无效1例,總有效率97.73%;止泻时长0.84±0.57日。住院时间3.54±1.53日。护理满意率100%;对照组:44例,治愈24例,有效15例,无效5例,总有效率88.64%;止泻时长2.54.±1.33日。住院时间7.78±2.68日,护理满意率79.55%(35/44);此外,优质组患者的焦虑、抑郁评分高于对照组。结论:急性肠炎临床护理过程中,采用优质护理干预能够起到更好的临床效果,受到广大患者的满意。
简介:【摘要】研究中医治疗慢性支气管炎急性发作的临床治疗效果。将我院 2019年 4月至 2020年 2月收治的 92例慢性支气管炎急性发作患者作为本次的研究对象,根据患者入院的先后次序将其随机分为给予常规西医治疗的对照组以及给予中医治疗的观察组,每组 46例患者,观察两组患者的临床治疗效果。经过治疗后发现观察组的 FEV1以及 FEV1/FVC数值均明显优于对照组, P< 0.05,具有统计学意义。通过中医治疗方式治疗慢性支气管炎急性发作期患者,能够有效改善患者肺部通气功能,真正达到帮助患者恢复身体健康的目的,治疗效果优于常规西医治疗,值得应用与推广。