简介：BackgroundThisarticlesummarizedtheexperienceofatrioventricularvalvereplacementoperationforfunctionalsingleventriclepatientswhoseatrioventricularvalvewasinsufficiency.Thefollow-uptimeofoperationwasarrangedfromearly-tomedium-term.MethodsFromJuly2009toJuly2015,therewere40patientsoffunctionalsingleventriclereceivingtheoperationofatrioventricularvalvereplacement,including23maleand17femalepatients.TheageatA-Vvalvereplacementwasrangedfrom6daysto32years(themediumageof9years),andthebodyweightrangedfrom2.7to57kg(themediumbodyweightof21.5kg).Moreover,theatrioventricularvalvereplacementwasperformedonallpatientsunderextracorporealcirculation.ResultsAtrioventricularvalvereplacementwasperformedon40patientswithfunctionsingleventricleinhospital,ofwhicheight(20.0%)diedinhospitalincludingtwoneonateandinfant(agerange:6days-2yearsold)accountingfor25%(2/8),Amongthem,sevenpatientsdiedoflowcardiacoutputsyndrometwopatientswithrepeatedhypoxemiaconcurrentinfectionafteroperation,andonewithbilateraldiaphragmaticparalysisandmalignantarrhythmia.Forthepatientssufferingthesevereperivalvularleakage,therewasareoperation,andthecardiacfunctionbeforethefirstoperationwasclassⅣ.OnepatientreceivedhearttransplantationfinallyforsevereheartfailureafterAVvalvereplacement.Fortherestofpatients,theircardiacfunctionrecoveredtoclassⅠ-Ⅱafteroperation.ConclusionsForfunctionsingleventriclepatientswithatrioventricularvalveregurgitation,themortalityrateofatrioventricularvalvereplacementcanbeacceptediftheoperationwasindicated.Forpatientswithsevereatrioventricularvalueregurgitation,theresultoftheoperationintheearlyandmediumtermwassatisfying.Thus,theatrioventricularvalvereplacementservedasausefultreatmentforpatientsdiagnosedofA-Vvalveregurgitationandfunctionalsingleventricle.

简介：ObjectivesToinvestigatetheclinicalmanifestationsofhypertrophiccardiomyopathy(HCM),andtofindouttheclinicalcluestoavoidmisdiagnosisandprovidereferenceforfutureclinicaldiagnosisandtreatment.MethodsAretrospectiveanalysisof42consecutivepatientswithHCMhospitalizedinourhospitalbetweenJanuary1995andDecember2002wasexplored.BasedonthefamilyhistoryofHCM,clinicalmanifestations,electrocar-diogram,echocardiogram,coronaryangiographyandleftventriculography,theclinicalcharacteristicsbetweenHCMpatientswithleftventricularoutflowtractobstruction(HOCM)andHCMpatientswithoutobstruction(HNOCM)werecompared.Thecausesofmisdiagnosisandlosingdiagnosiswereanalysis.Results13patientswereinHOCMgroupand29patientswereinHNOCMgroup.MorepatientswithsyncopewereinHOCMgroupthaninHNOCMgroup(6/13vs.2/29,P<0.05).PatientswithejectivemurmurwereinHOCMgrouponly(P<0.01).Leftventricularoutflowtractpressuregradient(LVOTPG)onlyobservedinHOCMgroup(P<0.01).Ventriculartachycardiawasseeninbothgroups.28outof42patients(66.67%)hadmisdiagnosis,and4outof42patients(9.53%)hadlosingdiagnosis.Thus,coronaryheartdisease(CHD)hadthehighestrateofmisdiagnosis.Therewere20CHDpatients(71.43%)among28patientswithmisdiagnosis.Hypertensionwasin3,congenitalheartin2,cerebro-embolismin2,andmyocarditisin1.ConclusionsForapatientwithfamilyhistoryorsuddendeathhistoryofHCM,unexplainedsyncopeepisodes,chestpain(angina),especiallyinyoung,anejectionmurmuralongtheleftsternumborder,thepresenceofnarrowanddeepQwaves,orinversionofgiantTwavesinV3-V6,atrialfibrillationand/orcerebra-embolismechocardiogramshouldbegiven.CAGandLVGarenecessaryonlyiftheresultofechoisnegative,andthepatientswithsuspectedHCMorCHD.

简介：Theriskofmyocardialinfarctionincreasesinpatientswithdiabetesmellitus.Theincidenceofmyocardialinfarctionissimilarinpatientswithtype2diabeteswithouthistoryofmyocardialinfarctionandinnon-diabeticpatientswithhistoryofmyocardialinfarction.DiabetesmellituswasconsideredasacoronarydiseaseequivalentbytheNationalCholesterolEducationProgram.Strictglycemiccontrolcanimprovethelong-termoutcomeofbothtype1andtype2diabetesmellitus.Whateverwithdiabeticornon-diabetic,strictglycemiccontrolwithintensiveinsulintherapycanreducethemortalityofcriticallyillpatientsinhospital.Aftermyocardialinfarction,therewouldbeaworseoutcomeforpatientswithpoorglycemiccontrol,whateverindiabeticornon-diabeticpatientswithstresshyperglycemia.Meanwhile,strictglycemiccontrolcanimprovetheoutcome.TheguidelineofAmericanCollegeofCardiology/AmericanHeartAssociationin2004onST-elevatedmyocardialinfarctionrecommendedinsulininfusionmaintainingtheeuglycemiaforpatientswithacutemyocardialinfarctionandcomplicatedconditions,whetherwithdiabetesmellitusornot,anditwasconsideredreasonabletoinfuseinsulinforallpatientswithhyperglycemiaduringtheperiodofacutemyocardialinfarction.Thispaperproposedaneffectiveandsafemethodforintravenousinsulininfusiontherapyfordiabeticpatientswithacutemyocardialinfarction.

简介：ObjectivesToinvestigatetheprevalenceofhypertensionanditsprimaryriskfactorsinpatientswithdilatedcardiomyopathy(DCM).MethodsThreehundredandsixty-twopatientswithDCM(DCMgroup)and401age-matchedresidents(controlgroup)wereenrolledrandomlyinthestudy,thehypertensiveprevalenceratewerecalculatedrespectivelyinthetwogroupsandwerecomparedwitheachother;thepatientsintheDCMgroupweredividedintotwosubgroups(hypertensionsubgroupandnon-hypertensionsubgroup)accordingtowhetherthepatientshavehypertension;theclinicaldatarelatedtobloodpressurewascomparedbetweenthetwosubgroups.ResultsTheprevalenceofhypertensioninDCMgroupwassignificantlyhigherthanthatinthecontrolgroup(32.8%vs.20.1%,P<0.01);Therewerenosignificantdifferencesontheage,gender,occupationandleftventricularejectionfraction(LVEF)betweenthetwosubgroups,butthemeanheartrateandthepercentageofpatientswhohadfamilyhistoryofhypertensionweresignificantlyhigherinthehypertensionsubgroupthanthatinthenon-hypertensionsubgroup(P<0.05andP<0.01).ConclusionsTheprevalenceofhypertensioninpatientswithDCMwashigh;TheincreasedactivityofsympatheticnervoussystemandthehypertensivegeneticfactormaybethemainriskfactorsofhypertensioninpatientswithDCM.

简介：BackgroundCircularRNAs(circRNAs)areendogenousnon-codingRNAsthatparticipateinregulatinggeneexpressionindiversebiologicalandpathologicalprocesses.TherolesofcircRNAsinatrialfibrillation(AF)havenotbeenwellelucidated.Inthepresentstudy,circRNAsprofileintheatrialappendagesofpatientswithAFwasexamined.MethodsHematoxylin-eosin(HE)andMassontrichromestainingwasperformedontheatrialappendagesofpatientswithsinusrhythm(SR)orAF.Expressionsoffibrosis,rennin-angiotensin-aldosteronesystem(RAAS)andinflammation-associatedgenesweredeterminedbyquantitativereversetranscriptionPCR(qRT-PCR).CircRNAsexpressionprofileinatrialappendageswasdetectedbycircRNAsmicroarray.qRT-PCRwasalsousedtodeterminetheexpressionof6representativedys-regulatedcircRNAs.PCRproductsofconcernedcircRNAswerefurtheridentifiedbygelelectrophoresisandDNAsequencingassay.ResultsMassontrichromestainingresultshowedthatfibrosiswasincreasedintheatrialappendagesofAFpatients.Thelevelsofcol1a1,Col3a1,fibrinectin-1(FN1),IL1-βandCRPmRNAexpressionweresignificantlyup-regulatedintheatrialappendagesofAFpatients.AcircRNAsarrayrevealedthatcircRNAsweredysregulatedintheatrialappendagesofAFpatients.qRT-PCRresultsdemonstratedthatcircRNA_100395wasup-regulated,circRNA_101270,circRNA_103820,circRNA_104168andcircRNA_100782weredown-regulatedsignificantlyintheatrialappendagesofAFpatientscomparedtoSRpatients.ConclusionsFibrosisandinflammationoccurintheatrialappendagesofAFpatients,whichcouldrelatetocircRNAsdysregulation.

简介：BackgroundBasedonpreviousstudies,afragmentedQRS(fQRS)complex,asapredictivebiomarkerofmyocardialscarringcondition,couldbeusedtopredicttheoutcomesofcardiacresynchronizedtherapy(CRT).However,thisconclusionisstilldebatable.MethodsFiftyischemicornon-ischemiccardiomyopathypatientsfailure(aged65±10yrs,34males,16females)withrefractoryheart,diagnosedbythecriteriaofNewYorkHeartAssociationreceivedCRT.TheECGsof18patientswithafQRScomplex(dividedbyDas)werecomparedwiththoseof32patientswithoutafQRScomplex,whowereevaluatedby12-leadECGbeforeCRT.Thepatientswerefollowedupforsixmonths,and12-leadECGandechocardiographywerereviewed.Atleast15%reductionintheleftventricularend-systolicvolume(LVESV)wasdefinedasrespondersaccordingtothedataobtainedforbetween-groupandintra-groupanalysis.ResultsSixpatients(33.3%)inthefQRSgroupand24patients(75%)inthenon-fQRSgrouprespondedwell.Inaddition,comparisonsofindicatorsfromsurfaceECGandechocardiography6monthsafterCRTshowedthatthenon-fQRSgroupbenefitedfromCRTsignificantlymorethanthefQRSgroup.ConclusionsThefQRScomplexhasgoodpredictivevalueforresponsivenesstoCRT.Non-fQRScomplexpatientswithrefractoryheartfailuremaybenefitmorefromCRT,andthesepatientsneedtoreceivethistreatmentasearlyaspossible.

简介：ObjectivesToevaluatethechangesoftheplasmaendothelinlevelinpatientswithdilatedcardiomyopathy,andtoinvestigatetherelationshipbetweentheplasmaendothelinlevelandtheseverityofheartfailure,heartsize,leftventricularfunctionandwithornotwithpulmonaryarterialhypertension;thechangesoftheplasmaendothelinlevelbeforeandaftertreatment.MethodsTheplasmaendothelinlevelof30patientswithDCM,30healthycontrolsubjects,andtheirLVEF,PAP,heartsize,plasmaendothelinlevelbeforeandaftertreatmentweredetermined.ResultsTheplasmaendothelinlevelinDCMgroupwassignificantlyhigherthanthatincontrolgroup(135.93±70.65pg/mL)vs(43.65±12.07pg/mL),P<0.05;therewasacorrelationbetweenETlevelandheartsize(r=0.4580,P=0.0109);therewasasignificantnegativecorrelationbetweenLVEFofDCMandETlevel(r=-0.6922,P=0.0021);anditwasasignificantpositivecorrelationbetweenETlevelandpulmonaryarterialhypertension(r=0.8974,P<0.0005).Aftertreatment,theETleveldecreasedsignificantlythanbeforeinDCMgroup(129.15±43.93pg/mL)vs(63.12±22.20pg/mL),P<0.05.ConclusionsPlasmaETlevelmaybeanewparameterofevaluatingseverityofheartfailure,efficacyoftherapyandprognosis.

简介：ObjectivesToanalyzethesix-minutewalktest(6MWT)andgasexchangeof5hearttransplantationpatientsandtoapproachthevariationtendencyofexercisetolerance,oxygenuptake(VO2)andheartratechronotropicresponse.Methods5casesofhearttransplantationpatients(age25～52years)wereundertaken6MWT6～30monthsafteroperation,synchronizinggasexchangingparametersweremeasuredbywirelessportableremotesensingK4B2gasanalyzer,51normalcontrolswerecompared.ResultsThesix-minutewalkdistance(6MWD)of5patientswere(592.6±26.7)m(558～625)m,theascendingtendencyduringexercisewasslower,themaximumheartrateswere80%±6%ofage-predictingmaximalheartrate,lowerthannormalcontrol(86%);theendpointVO2/kgwere(21.8±1.4)mL/min·kg(19.94～23.60)mL/min·kg.ConclusionsThe6WMDandVO2of5patientsreachednormalrange,buttheheartratechronotropicresponseandVO2ascendingtendencywereslowerthanthoseofnormalcontrols.

简介：BackgroundArrhythmogenicrightventricularcardiomyopathy(ARVC)isamajorcauseforsuddencardiacdeathduetoventriculartachycardia.Litterisknownaboutitslong-termoutcomesinChineseARVCpatients.Thepurposeofthisstudywastoevaluatethelong-termclinicaloutcomesinpatientswithARVCandtoclarifytheriskfactorsofcardiacevents.MethodsFortysubjectsfulfillingmodifiedTaskForcecriteriawereincludedinthisstudy.Informationonclinicalpresentation,electrocardiographicandcardiacimagingfindings,andlong-termoutcomeofcaseswereinvestigated.ResultsAveragefollow-upperiodfromonsetwas57.5±42.6months.Themeanageatonsetofsymptoms(32.2±12.7years)andmalepredominance(85.0%)weresimilartothatreportedinotherstudies.Palpitationswerethemostfrequentsymptom(82.5%).T-waveinversionwasthemostcommonpresentingabnormalityonresting12-leadECG(75%).Ventriculartachycardiawithleftbundlebranchblockmorphologywassubsequentlydocumentedinatotalof28(70%)subjectsduringastudyperiod.Thecumulativemortalityratewas7.5%.ConclusionClinicalpresentationinChineseARVCpatientswassimilartothatreportedinotherstudies.ARVCisassociatedwithearlymortalitythatisdifferenttoothercountrypopulation.

简介：Toinvestigatetherelationshipbetweenthechronotropicincompetenceandangiographicseverityofcoronaryarterydisease,andtheclinicalvalueofinappropriatechronotropicresponsesinexercise.MethodsCoronaryangiographywasperformedin130patientssuspectedordiagnosedascoronaryheartdisease(CHD),andangiographicseverityofcoronaryarterydiseasewasquantitatedbyDukescoreandGensiniscore.Thepatientsweredividedinto4groups:non-CHDgroup(39cases),CHDgroupwithonlyonecoronaryarteryinvolved(CHD1,30cases),CHDgroupwithtwocoronaryarteriesinvolved(CHD2,31cases)andCHDgroupwiththreecoronaryarteriesinvolved(CHD3group,30cases).Amonthbeforecoronaryangiography,symptom-limitedbicycleergometorexercisehadbeenaccomplished,thechronotropicresponsehadbeenmeasuredandexpressedasratioofheartratereserve(HRR)andthemaximalage-predictedheartrateachieved(rHR).ResultsAnalysisofvarianceshowedthatrHRandHRRweremuchsignificantlylower(allP<0.01)inCHD2group(rHR0.793±0.078,HRR0.626±0.110)andCHD3group(rHR0.775±0.065,HRR0.586±0.125)thanthatinnon-CHDgroup(rHR0.888±0.062,HRR0.798±0.105)andCHD1group(rHR0.857±0.084,HRR0.735±0.146).rHRwassimilarbothbetweennon-CHDgroupandCHD1group(P>0.05)andbetweenCHD2groupandCHD3group(P>0.05).HRRhasnodifferencebetweenCHD2groupandCHD3group(P>0.05),butwassignificantlydifferentbetweennon-CHDgroupandCHD1group(P<0.05).TherewasasignificantlynegativecorrelationbetweenrHR,HRRandDukescore(r=-0.554,-0.578,respectively,allP<0.01),Gensiniscore(r=-0.453,-0.467,respectively,allP<0.01).CHDproportionreached75%inpatientswhohadpositiverHR(orHRR)andnon-STdepression.Diagnosticvalue[sensitivity0.868(P<0.01),0.846(P<0.01),specificity0.462,0.462,accuracy0.746(P<0.05),0.731,positivepredictivevalue0.790,0.786,negativepredictivevalue0.600,0.563,respectively]ofrHR<85%orHRR<72%whichwereusedasan

简介：Palliativecareisthereliefofsymptomswithoutdealingwiththeunderlyingcause,e.g.useofanalgesia,torelievepain.Theuseofsuchanagentalleviatesthesymptomswithoutcuringtheunderlyingdisease.Thisisthetypeofcareforpatientswithseriousillnesses.Itfocusesonimprovingqualityoflife,notjustinyourbody,butalsoinyourmindandspirit.Thereisathinlinebetweenpalliativecareandhospicecare.

简介：ObjectivesToexploretheeffectoflosartanoncardiacandrenalfunctioninpatientswithchronicheartfailure(CHF).MethodsSixty-fivepatientswithCHFweredividedintotwogroupsusingarandomized,controlandsingleblindmethod:losartangroup(n=30)andconventiongroup(n=35),withatreatmentcourseof8weeksforbothgroups.TheconcentrationsofcystatinC(cysC)inserum,microamountalbumin(MA)inurineweremeasuredbyimmunoturbidimetry.Theconcentrationofaquaporin-2(AQP-2)wasdeterminedbyenzyme-linked-immunosorbentassay(ELISA)andtheheartcontractilefunctionwasmeasuredbyechocardiographybeforeandaftertreatmentrespectively.ResultsComparingwithroutinetreatmentgroup,leftventricularend-diastolicdimension(LVEDd)decreasedsignificantly,whileleftventricularejectionfraction(LVEF)andleftventricularfractionalshortening(LVFS)increasedsignificantlyinlosartangroup.ThelevelsofcysCinserumandMA,AQP-2inurineweresignificantlylowerinlosartangroupthaninroutinetreatmentgroup.ConclusionLosartancanimprovecardiacandrenalfunctioninpatientswithCHF.

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简介：ObjectivesToexaminepatientdelay(PD)inseekingtreatmentamongpatientswithST-elevationmyocardialinfarction(STEMI)andtoidentifyfactorsinfluencingPD.MethodspatientswithSTEMIweredividedintotwogroupsbasedonPD:ShortPDgroup(PD≤60minutesafteronsetofsymptoms)andlongPDgroup(>60minutesaftersymptomonset).Aquestionnairedevelopedtoassessdemographiccharacteristics,clinicalfactorsandpsychologicalfactors.Patientswereinterviewedwithin72hoursofadmissionto2hospitals.Results329consecutiveconfirmedSTEMIpatients(Meanage61years;72.5%men)withamedianPDof90minandapre-hospitaldelaytime170minwerestudied,PDwaslessthan1hoursin47.4%ofpatients,whilemorethan1hoursin52.6%,Inunivariateanalyses,patientswithshortPDwerewitnessonset,progresscourseofsymptom,severepain,deathanxiety,knowingAMIasadeadlydiseaseanditspresentation,takingthesymptomseriously.PatientswithlongerPDwereage≥65year,nocturnalonset,experiencedtheirsymptomsathome,gradualonset,’waitedtoseewhethersymptomsdisappeared’,’worriedabouttroublingothers’,’tookpainmedication’andpreinfarctionangina.Astepwisemultipleregressionanalysisfurthersuggestedthatthefollowinginde-pendentcontributorstoalatedecisiontoseekmedicalhelp(relativerisk,95%confidenceinterval):takingpainmedication(15.97;1.70～149.8),wantingtowaitandsee(6.46;1.92～21.74),notwantingtobotheranybody(6.42;2.87～14.34),preinfarctangina(2.73;1.20～6.19),age≥65years(2.51;1.15～5.48),gradualonset(2.40;1.05～5.44),severepain(0.38,0.17～0.85),witnessonset(0.27,0.10～0.70),takingsymptomsseriously(0.019;0.08～0.46).ConclusionsAge≥65years,gradualonset,witnessonset,severepain,preinfarctangina,emotionalresponsesandcopingstrategiesaretheindependentfactorsassociatedwithpatientdelayordecisiontimeinpatientswithAMI.Emotionalresponsesandcopin

简介：Toevaluatetheeffectofatrovastatintherapyonborderlinevulnerablelesionsinpatientswithacutecoronarysyndrome(ACS).MethodsPatientswithACSunderwentcoronaryangiography(CAG)andintravascularultrasound(IVUS)investigation.Patientswithculpritvulnerableborderlinelesionswereenrolled.Nocoronaryinter-ventionwasperformedontheselesions.Allthepatientsreceivedatrovastatintherapyfor12monthsandunderwentclin-icalfollow-upalongwithIVUSfollow-up.Crosssectionarea(CSA)ofthetargetedlesion,CSAofthereferencearter-ies(extraelasticmembrane),minimallumenCSA,andplaqueareaweremeasuredatbaselineandfollow-ups.Ad-verseeventsincludedrecurrentangina,recurrentmyocardialinfarction,revascularizationanddeath.ResultsNoad-verseeventswasreportedduringfollow-upperiod.Comparedwithbaselinedata,thelevelofApoBdecreasedsignifi-cantlyattheendofthestudy(0.589±0.136g/Lvs0.681±0.132g/L,P=0.03).Boththepercentdiametersteno-sisandthepercentareastenosisdetectedbyCAGdisplayedminimalchange((62.50±10.21)%vs(54.79±12.35)%,P=0.48and(58.61±8.36)%vs(48.18+10.56)%,P=0.78).DetectedbyIVUS,theminimallu-minalCSAofthetargetedlesionincreasedsignificantly(6.32±2.42mm2vs5.63±2.51mm2,P<0.01),theplaqueareaandCSAstenosisdecreased(7.70±2.19mm2vs8.17±2.55mm2,P<0.05and56.94±8.47%vs61.4±110.34%,P<0.01).Atotalof25softplaques(50%)transformedintofibrousplaque.ConclusionsAtro-vastatintherapystabilizesborderlinevulnerableplaqueandreversesatherosclerosisprogressioninpatientswithACS.

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简介：ObjectivesToevaluatetheeffectsofn-3fattyacidsonthecoronaryheartdiseasepatients.MethodsFromSeptember2007toMarch2008,60patientswithcoronaryheartdiseasewererandomlyassignedton-3fattyacidsgroup(groupN)andcontrolgroup(groupC).BothgroupsreceivedstandardcoronaryarterydiseasesecondarypreventiontreatmentandgroupNalsoreceivedeicosapentaenoicacid(EPA)1.8gplusdocosahexaenoicacid(DHA)1.2gperdayfor12weeks.Plasmatriacylglycerols,totalcholesterol,low-densitylipoproteincholesterol(LDL-C),high-densitylipoproteincholesterol(HDL-C)andbloodpressureweremeasuredbeforeandafterthestudy.ResultsPlasmatriacylglycerols,bloodpressureandLDL-ClevelwereloweringroupNaftern-3fattyacidstreatmentwhilenochangewasfoundingroupC(P<0.05).HDL-Clevelslightlyincreasedandtotalcholesterollevelslightlydecreasedaftern-3fattyacidsbutbothchangewerenotsignificant(P>0.05).ConclusionsN-3fattyacidshavebeneficialeffectsonthecoronaryarterydiseasepatients.

简介：ObjectivesTocomparetheshortandmid-termoutcomesincasesofpercutaneoustransluminalcoronaryangioplasty(PTCA)inpatientswithunstablevstableangina.MethodsPatientsselectedforPTCA/stentingweredividedintotwogroups,onewithstableanginapectoris(SAgroup,n=92)andonewithunstableanginapectoris(UAgroup,n=112).Theoutcomesofcoronaryangiographies(CAG),initial(30-d)successoftheprocedure,andfollow-upstatusinthetwogroupswerecompared.ResultsBaselinecharacteristicsweresimilar,althoughthepatientswithunstablesymptomsmorefemales(P<0.05),andhadahigheraverageCCSclass(P<0.05)andahigherincidenceofpostinfarctionangina(P<0.01).Thefrequencyof’complexstenosisinpatientswithunstableanginawashigherthanthatofpatientswithstableangina,33%v20%(P<0.01).Atotalof309vesselsacceptedtheprocedure;including210stentsweresuecessfullydeliveredto156patients.143and67stentswereimplantedinthe

简介：BackgroundVocalcordmovementdisorder(VCMD)isalaryngealdisordercharacterizedbyparadoxicaladductionofthevocalcordsduringininspiration,expirationorboth.ThenursingexperienceofpatientswithVCMDafteraorticdissectionsurgeryislimited.MethodsWeretrospectivelyanalyzedtheclinicaldataandnursingrecordsof269patientsafteraorticdissectionsurgeryinGuangdongGeneralHospitalbetweenMay2010andMay2012.Weobservedthepatients’pronunciation,andjudgediftherewasdysphagiaundergoingwaterdrinkingtesttwohoursafterextubation,toconfirmwhetherpatientshadVCMD.ResultsSeventeenpatientshadVCMDafteraorticdissectionsurgery,ofwhom2sufferedhoarseness,3haddysphasiaand12hadbothhoarsenessanddysphasia.Aftertimelytreatmentandcarefullynursing,allthepatientsrecoveredwell.ConclusionsWiththeenhancedcareofpatientswithaorticdissection,observinghoarsenessappearanceanddrinkingexperimentimmediatelyafterextubationcandetectVCMDassoonaspossible.Furtherrehabilitationtrainingandpsychologycarecanpreventbuckingandaspirationeffectively,andpromotingrecoveryandimprovingpatient’slifequality.