简介:例l女,57岁。因下肢浮肿,于2006年2月14日来院就诊。患者糖尿病史11年,长期口服降糖药。血糖:空腹9.5mmol/L,餐后2h25.1mmol/L,Ccr115.26ml/min,尿微量白蛋白(UAER)116.9μg/min。诊断:2型糖尿病,糖尿病性肾病。停口服降糖药,给予重组人胰岛素(甘舒霖30R)早餐前30min12u皮下注射,20min后自觉口干、耳鸣未介意。晚餐前30min再次皮下注射甘舒霖30R8u,10min后出现蹩气,口干难忍,口唇麻木肿胀。局部皮肤于注射后1-2min瘙痒、红肿,次日声音撕哑,咽痛加重。换用重组人胰岛素(诺和灵)、(优泌林)、动物胰岛素皮下注射均有上述反应。改口服格列喹酮(糖适平)150mg/d,3周后血糖:空腹6.2mmol/L,餐后2h8.1mmol/L。上述反应未出现。
简介:H3,ahomogeneousacidicpolysaccharidewasobtainedfromtheseedsofCuscutachinensisLam.Itsstructurewascharacterizedforthefirsttimebychemicalandspectroscopicmethodstobeahighlybranchedheteropolysaccharidewithmeanmolecularweightofmorethanlxl0^6.Itwascomposedof1,6-1inked-β-DGalp,1,4-linked-β-DGalp,1,4-1inked-β-DGalA,1,3,6-1inked-β-DGalpand1,2,4-1inkedRhap,withbranchingpointsatO-2or0-4of1,2,4-1inkedRhapand0-3of1,3,6-1inked-β-DGalp.Itssidechainsincluded1-1inkedAraf,1,5-1inkedArafand1,3,5-1inkedArafatO-3of1,6-1inkedGalpinthemainchain.