简介：西藏Shannan红鹿自然保护区是西藏的红鹿的地理分发的中心。这份报纸论述烘便的小团组在绿植物的时期期间在2013和2014期间收集了的199红鹿的DNA分析的结果。我们成功地与12microsatelliteloci从87个DNA小团组和坚定的单个鉴定提取了DNA。我们在R软件与Capwire评估了人口和各种各样的人口估计的基因差异。87个成功地提取的小团组来自50个个人。在人口，等位基因的平均数字是7.58吗？？

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简介：Influenceofpulsedpowertransmissiononradiowaveenvironmentisinvestigated.Thepowerpulsesaretransmittedintermittentlyinpulsedpowernetworkthatisalreadyproposedforanalternativeofupcomingsmartgrids.Incontrasttoconventionalpowertransmissionwithcontinuouselectriccurrentoflowfrequencysinewave,pulsedpowertransmissionmayaffectsurroundingfieldwithhighfrequencyradionoises.Inthispaper,basedontheanalysisofelectricfieldstrengtharoundapowerline,theradionoisesgeneratedbyvariousformsofpulsedpowertransmissionareevaluated.Asaresult,twopointsarederived.First,thoughthetotalofgeneratedradionoisepowerobviouslyexceedsthatofconventionalpowertransmissions,peakstrengthofelectricfieldratherfallsbehindtheconventionalone.Second,concerningtheinfluenceontheradiowaveofthelowestfrequency40kHzthatisactuallyusedforstandardtimeandfrequencysignal,thenoiseintensitypossiblyexceedstheweakradiosignaltoleranceaccordingtotheshapeofeachpowerpulsetransmitted.

简介：Openwaveguidesarewidelyusedinmodernphotonicdevices,suchasmicrostructuredfiberfiltersandsensors.Theirabsorptionandtransmissionspectraarethemostimportantpropertiesindeterminingtheoverallperformanceofthephotonicdevices.Theimaginarypartsoftheireigenvalueshavebeencommonlyusedtocalculatetheabsorptionandconsequentlythetransmissionspectra.Hereweshowthatthisformulismisgenerallyincorrectandnotconsistentwiththesimulationresultsobtainedbythebeampropagationmethod.Werevisitthefundamentaltheoryfortheabsorptionofopenwaveguidesandpresentageneralformulism.Wefoundthatparity-time-symmetrytransitions,whichhavebeenconventionallyignored,playacriticalroleinthepropertiesofthecoupledwaveguide.Theabsorptionandtransmissionarehighlydependentonthephysicallengthofthesystem.Onthebasisofourfindings,optimizationcriteriafordesigningphotonicsensorsandfiltersarepresented.

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简介：AIMToverifythevalidityoftheendoscopyguidelinesforpatientstakingwarfarinordirectoralanticoagulants(DOAC).METHODSWecollecteddatafrom218patientsreceivingoralanticoagulants(73DOACusers,145warfarinusers)and218patientsnotreceivinganyantithrombotics(age-andsexmatchedcontrols)whounderwentpolypectomy.(1)Weevaluatedpost-polypectomybleeding(PPB)riskinpatientsweassessedtherisksofPPBandthromboembolismbetweenthreeACmanagementmethods:DiscontinuingACwithheparinbridge(HPB)(endoscopyguidelinerecommendation),continuingAC,anddiscontinuingACwithoutHPB.RESULTSPPBratewassignificantlyhigherinwarfarinusersandDOACuserscomparedwithcontrols(13.7%and13.7%vs0.9%,P<0.001),butwasnotsignificantlydifferentbetweenrivaroxaban(13.2%),dabigatran(11.1%),andapixaban(13.3%)users.Twothromboemboliceventsoccurredinwarfarinusers,butnoneinDOACusers.Comparedwiththecontinuinganticoagulantgroup,thediscontinuinganticoagulantwithHPBgroup(guidelinerecommendation)hadahigherPPBrate(10.8%vs19.6%,P=0.087).ThesefindingsweresignificantlyevidentinwarfarinbutnotDOACusers.OnethromboticeventoccurredinthediscontinuinganticoagulantwithHPBgroupandthediscontinuinganticoagulantwithoutHPBgroup;noneoccurredinthecontinuinganticoagulantgroup.CONCLUSIONPPBriskwassimilarbetweenpatientstakingwarfarinandDOAC.Thromboembolismwasobservedinwarfarinusersonly.TheguidelinerecommendationsforHPBshouldbere-considered.

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简介：Whenadielectricmeta-atomisplacedintoasubwavelengthmetallicaperture,20-foldenhancedelectromagnetictransmissionthroughtheapertureisrealizedatthemeta-atom’sresonantfrequency.Additionally,whentheincidentelectromagneticpowerincreases,thermalenergygatheredbythemeta-atom,whichisconvertedfromelectromagneticlosses,cancausethemeta-atom’stemperaturetoincrease.Becauseofthehightemperaturecoefficientofthemeta-atom’sresonantfrequency,thistemperatureincreasecausesablueshiftinthetransmissionpeak.Therefore,thisfrequency-dependentenhancedelectromagnetictransmissionevenproducesanonlineareffectatlowincidentpowers.Overanincidentpowerrangefrom0to20dBm,measuredandsimulatedspectranearthemeta-atom’sresonantfrequencyshowdistinctlynonlineartransmission.

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简介：ThisresearchinvestigatesChineseEnglishasaforeignlanguage(EFL)learners’oralEnglishcommunicationstrategies(CSs)andoralEnglishlearningstrategieswhenstudyinginanEnglishspeakingcontext.Forthispurpose,theresearcherconductedsemi-structuredinterviewswithfourChineseEFLlearnerswhoarestudyingintheUKwithdifferentEnglishproficiencies,analysedtheirstrategiesoforalEnglishlearningandcommunication,andcomparedchangesinstrategiesduringoneyearofstudyingabroad.Itshowedthat,whenconfrontedwithdifficultiesinoralEnglishlearning,participantsusuallyemployedaffectivestrategiestoadapttothenewlearningenvironment.Andlearnersfromdifferentlevelshavedifferentperformancesinmeta-cognitivelearningstrategiesuse.Inaddition,theEnglishspeakingcontextmadesomedifferencestolearners’learning.WhenitcomestoCSs,ontheonehand,strategies,suchasnegotiationformeaning,andsoon,wereshownasbeingprimarilyusedbyparticipants,eventhoughparticipantsfromdifferentlevelsmighthavesomedifferencestosomeextent.Ontheotherhand,strategieslikelessactivelistener,andsoon,wererelativelylessemployedbyparticipants.TheseresultswouldprobablyhelplearnersandteachersunderstandoralEnglishlearningandteachinginnativecontextsbetter.

简介：人参皂甙Rh2(Rh2)是在人参属人参的主要bioactive人参皂甙之一。然而，Rh2的口头的bioavailability是低的，与P-glycoprotein(P-gp)，CYP3A4正在被报导是主要因素。现在的学习的目的是象Rh2的bioactivity一样在口头的bioavailability上决定胡椒碱的提高的效果。P-gp和CYP3A4上的胡椒碱的禁止的效果用一个Caco-2单层模型和recombinant被决定CYP3A4新陈代谢的系统分别地。口头的Rh2的pharmacokinetics(10个mg房间。混合物1和3显著地与是的IC50价值禁止了HeLa房间的增长3.02???????┱??????????????愠摮潲牧灡潨楬敤？？

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简介：AspatientsinEastAsiaage,theprevalenceofage-relatedandchronicdisease,includingnonvalvularatrialfibrillation,mayincrease.Althoughwarfarinhasbeentheprimarychoiceofanticoagulantforthepreventionofstrokeandsystemicembolicevents,theuseofdirectoralanticoagulants(DOACs)isincreasing.DOACsdonotrequiremonitoringoftheinternationalnormalizedratiotodeterminetheoptimaldose,andhavealowerpotentialforfoodanddruginteractions,improvedbenefit-riskprofiles,andaquickeronsetandoffsetofactionrelativetowarfarin.Thepivotalphase3trialsforeachoftheDOACs–dabigatran,rivaroxaban,apixaban,andedoxaban–includedatleastsomeEastAsianpatients.Additionally,severalclinicaltrialswereconductedspecificallyforEastAsianpatients.ThisreviewdiscussespatternsandpredictorsofanticoagulantuseinEastAsianpatientswithnonvalvularatrialfibrillation,summarizescurrentguidelinerecommendationsforEastAsianpatients,detailstheprimaryresultsdemonstratingthesafetyandefficacyofDOACsinEastAsianpatientsrelativetonon–EastAsianpatients,providesreal-worlddatasupportingthephase3testingresults,andaddressestheclinicalprofileofDOACsinEastAsianpopulations,includingpatientsathighriskofstroke.

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