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  • 简介:AbstractBackground:Oncomelania hupensis is only intermediate snail host of Schistosoma japonicum, and distribution of O. hupensis is an important indicator for the surveillance of schistosomiasis. This study explored the feasibility of a random forest algorithm weighted by spatial distance for risk prediction of schistosomiasis distribution in the Yangtze River Basin in China, with the aim to produce an improved precision reference for the national schistosomiasis control programme by reducing the number of snail survey sites without losing predictive accuracy.Methods:The snail presence and absence records were collected from Anhui, Hunan, Hubei, Jiangxi and Jiangsu provinces in 2018. A machine learning of random forest algorithm based on a set of environmental and climatic variables was developed to predict the breeding sites of the O. hupensis intermediated snail host of S. japonicum. Different spatial sizes of a hexagonal grid system were compared to estimate the need for required snail sampling sites. The predictive accuracy related to geographic distances between snail sampling sites was estimated by calculating Kappa and the area under the curve (AUC).Results:The highest accuracy (AUC = 0.889 and Kappa = 0.618) was achieved at the 5 km distance weight. The five factors with the strongest correlation to O. hupensis infestation probability were: (1) distance to lake (48.9%), (2) distance to river (36.6%), (3) isothermality (29.5%), (4) mean daily difference in temperature (28.1%), and (5) altitude (26.0%). The risk map showed that areas characterized by snail infestation were mainly located along the Yangtze River, with the highest probability in the dividing, slow-flowing river arms in the middle and lower reaches of the Yangtze River in Anhui, followed by areas near the shores of China’s two main lakes, the Dongting Lake in Hunan and Hubei and the Poyang Lake in Jiangxi.Conclusions:Applying the machine learning of random forest algorithm made it feasible to precisely predict snail infestation probability, an approach that could improve the sensitivity of the Chinese schistosome surveillance system. Redesign of the snail surveillance system by spatial bias correction of O. hupensis infestation in the Yangtze River Basin to reduce the number of sites required to investigate from 2369 to 1747.

  • 标签: Schistosomiasis Oncomelania hupensis Snail infestation Yangtze River Random forest Spatial sampling Machine learning China
  • 简介:ProteomicshasbeenwidelyusedinthelastfewyearstolookfornewbiomarkersanddecipherthemechanismofHIV-hostinteraction.Herein,wereviewtherecentdevelopmentsofHIV/AIDSproteomicresearch,includingthesamplesusedinHIV/AIDSrelatedresearch,thetechnologiesusedforproteomicstudy,thediagnosisbiomarkersofHIV-associateddiseaseespeciallyHIV-associatedneurocognitiveimpairment,themechanismsofHIV-hostinteraction,HIV-associateddementia,substanceabuse,andsoon.Intheendofthisreview,wealsogivesomeprospectsaboutthelimitationandfutureimprovementofHIV/AIDSproteomicresearch.

  • 标签: 蛋白质组学 艾滋病毒 生物标志物 感染 主机 认知功能障碍
  • 简介:Anewmethodisproposedforsynthesizingintermediateviewsfromapairofstereoscopicimages.Inordertosynthesizehigh-qualityintermediateviews,theblockmatchingmethodtogetherwithasimplifiedmulti-windowtechniqueanddynamicprogrammingisusedintheprocessofdisparityestimation.Thenocclusiondetectionisperformedtolocateoccludedregionsandtheirdisparitiesarecompensated.Aftertheprojectonoftheleft-to-rightandright-to-leftdisparitiesontotheintermediateimage,intermediateviewissynthesizedconsideringoccludedregions.Experimentalresultsshowthatoursynthesismethodcanobtainintermediateviewswithhigherquality.

  • 标签: 中间视图合成 差异估计 动态规划 阻塞检测
  • 简介:TheEducationalResourceDevelopmentforHighSchoolExchangeProgramisstillacceptingapplicationsforhostfamiliesfortheupcomingschoolyear.

  • 标签: 高中 英语 注释读物 阅读欣赏
  • 简介:一本昆虫食谱的范围被产卵离子行为主要决定,这大部分被知道,主要在有象Zabrotessubfasciatus那样的endophytic幼虫的种类。然而,决定主人选择的贴近的因素和导致主人的扩大或减小的随后的步数并且偶尔的主人移动大部分是未知的。我们分析了决定Z的主人偏爱的各种各样的因素。通过评估的subfasciatus:(i)Z的一张野人口的产卵离子偏爱。平常的主人(豆子)和不平常的主人(小扁豆,嘴豆和酱油)上的subfasciatus,和后代的表演;(ii)为开始为主人增加偏爱的人工选择经常选择的更少;(iii)在二张不同人口之间的产卵离子行为的比较(在豆子或嘴豆为~饲养了30代,分别地);(iv)产卵离子在平常、不平常的主人上预定;并且偏爱层次的(v)鉴定。当人口在不太经常接受的主机上通过几代时,我们发现当使用不平常的主机时,在性能和偏爱之间没有关联并且偏爱层次仅仅稍微变化。我们也为在少些比较喜欢的主人上增加产卵离子发现了积极回答到人工选择;然而,当主人选择实验包含了平常的主人的二个变化时,反应比选择什么时候包含平常、不平常的主人快。最后,甲壳虫在一位不平常的主人(嘴豆)上高耸了因为26代在平常、不平常的主人上显示出类似的好健康,显示一位新主人的使用未必确实导致原来的主人上的性能的损失。不过,这张人口比原来的人口的在平常的宿主上显示出更低的健康,建议可以贡献一拓宽这昆虫种的饮食的内在的部分交易现象。

  • 标签: 人工选择 菜豆属 进化方式 昆虫
  • 简介:Anovelintermediatefluidvaporization(IFV)technologyforLNGre-gasificationprocesswithspiral-woundheatexchangingtubesisproposed.ThenewIFVprojectcombinestheadvantageofrunningtheshellandtubeheatexchangersathighpressurewiththeadvantageofcompactspaceofheatexchangers.Thermalanalysisonthetwoprocessesofforcedconvectionandvaporizationtypeheattransferinthespiralwoundtubesandvaporcondensation/re-boilingtypeofheattransferviaintermediatefluidinshellsideshowsthefeasibilityofthispromisingtechnology.

  • 标签: 热流体 汽化器 缠绕管 管壳式换热器 气化过程 热交换管
  • 简介:OnApril1,CAFIUworkedtogetherwiththeFriedrichEbertStiftung(FES)BeijingOfficeinhostingaRoundtablemeetingon"EnergyTransitionandSustainableEconomicPolicy".InvitedtoattendtheroundtablemeetingwereProf.Franz-JosefBr(u|¨)ggemeier,renownedGermansociologistandeconomist,Prof.LiHengyuan,formerDirector-Generalof

  • 标签: German Director ECONOMIST renowned worked attend
  • 简介:Intermediate Mass Fragment Emission in Ar+Ag CollisionsIntermediateMassFragmentEmissioninAr+AgCollisions¥WuEnjiu;ZhengJiwen;W...

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  • 简介:Thesuccinylationofcornstarchbyslurryreactionhasbeenstudiedusingsodiumhydroxideascatalyst.SeveralreactionparametersafJectingthesuccinylationwereinvestigatedincludingtheconcentrationofstarchinwater,theratioofsuccinicanhydridetostarch,thereactiontimeandthereactiontemperature.Thefavorableconditionsforanintermediatedegreeofsubstitution(DS)andreasonablyhighreactionefficiency(RE)arepH8.5~9.0,50%starchbyweighttowater,succinicanhydridetostarchI/I(w/w),reactiontime4h,reactiontemperature30℃Undertheseconditions,theDSof0.45andREof28%wereachieved.Theadditionofanadequateamountofcrosslinkingagentimpartedstarchsuccinatewaterabsorbency.

  • 标签: 淀粉酶 琥珀酐 淀粉琥珀
  • 简介:Pinealapoplexyisarareclinicalpresentationofpinealparenchymaltumors.Wereportthecurativetreatmentofacaseofpinealparenchymaltumorofintermediatedifferentiationwithspontaneousapoplectichemorrhage.Thiscaseisshownthroughcomputedtomographyandmagneticresonanceimagingofthebrain,andisconfirmedviahistopathologicalstudies.Recurrentupwardgazeparesiswasobservedafterthestereotacticbiopsy.Theparesisrequiredanexpeditioustumorresection.Themechanismofthepinealapoplectichemorrhageremainsunclearalthoughithasbeenobservedindifferentpinealregionlesions.Clinicalandradiologicalevidenceofthecure5yearspost-surgeryisavailable.

  • 标签: 松果体 肿瘤 中风 分化 计算机断层扫描 临床表现