简介：Forthelargenumberofnonlineardegradationdevicesexistinginaproject,theexistingmethodshavenotsystematicallystudiedtheeffectsofrandomeffectontheremaininglifetime(RL),theaccuracyandefficiencyoftheparametersestimationarenothigh,andthecurrentdegradationstateofthetargetdeviceisnotaccuratelyestimated.Inthispaper,anonlinearWienerdegradationmodelwithrandomeffectisproposedandthecorrespondingprobabilitydensityfunction(PDF)ofthefirsthittingtime(FHT)isdeduced.Aparameterestimationmethodbasedonmodifiedexpectationmaximum(EM)algorithmisproposedtoobtaintheestimatedvalueoffixedcoefficientandthepriorivalueofrandomcoefficientinthemodel.Theposteriorvalueoftherandomcoefficientandthecurrentdegradationstateoftargetdeviceareupdatedsynchronouslybythestatespacemodel(SSM)andtheKalmanfilteralgorithm.ThePDFofRLwithrandomeffectisdeduced.AsimulationexampleisanalyzedtoverifythattheproposedmethodhastheobviousadvantageovertheexistingmethodsinparameterestimationerrorandRLpredictionaccuracy.

简介：<正>Therewasoncean11-year-oldboywhowentfishingeverytimehewenttoanislandinthemiddleofaNewHampshirelake.Onthedaybeforebass(巴斯鱼)seasonopened,heandhisfather

简介：整个故事在情人节那天发展到了高潮。洛丽用白胶在卡片里信手拼出了非常漂亮的“我爱你”，并在上面洒了发光屑。我将这张卡片反反复复看了三、四十遍。然后把它藏到了短袜里……回到餐馆。我尽力用最纯洁的吻封好信封。将卡片放在我们的桌子上，然后默默地走了出去。

简介：Itwasafreezingday,whenIpickedupawalletinthestreet.TherewasnothinginsidebutaletterthatwassignedHelen.OnthetomenvelopeIfoundtheretumaddress,soIcalledanInformationline.Theoperatoraskedmetoholdon,andshecamebackon

简介：Anewopticalfiberfluorometricthermometerbasedonthetemperaturedependenceofthefluorescencelifetimeofphosphorisdescribed.Thephase-lockeddetection(PLD)systemisusedtomeasurefluorescencelifetime.Thecharacteristicsofthermmeterarediscussedandtheexperimentresultsaregiven.

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简介：Anovelfluorescencelifetimeimagingmicroscopy(FLIM)workingwithdeepUV240–280nmwavelengthexcitationshasbeendeveloped.UV-FLIMisusedformeasurementofdefect-relatedfluorescenceanditschangesuponannealingfromfemtosecondlaser-inducedmodificationsinfusedsilica.ThisFLIMtechniquecanbeusedwithmicrofluidicandbiosamplestocharacterizetemporalcharacteristicsoffluorescenceuponUVexcitation,acapabilityeasilyaddedtoastandardmicroscope-basedFLIM.UV-FLIMwastestedtoshowannealingofthedefectsinducedbysilicastructuringwithultrashortlaserpulses.Frequency-domainfluorescencemeasurementswereconvertedintothetimedomaintoextractlongfluorescencelifetimesfromdefectsinsilica.

简介：正电子歼灭一生光谱学(伙伴)是一种强大的技术在聚合物学习免费体积。ortho电子偶素(o-Ps)的一生，一个电子的一个界限状态和一个正电子，当紧张能被用来描绘毛孔的数字时，能被用来估计毛孔尺寸。(2,6-dimethyl-1,4-phenyleneoxide)(SPPO)根据在在sulfonated的一生系列，半径和部分免费体积的长寿o-Ps部件的价值，poly，有LiCl的不同数量的膜被计算。与LiCl的增加的数量，免费体积半径和部分免费体积第一增加了然后减少，这被发现。在在提取的水里沉浸膜以后，免费体积半径和部分免费体积在膜随着不同的水集中变化了。

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简介：随着P4构架的成熟。芯片组发展也越来越缓慢．除了对周边(SATA、IEEE1394等)设备支持的升级外，我们很难再看到能带来巨大性能提升的产品。硕泰克SL-PT880E—RL主板采用VIAPT880芯片组．威盛这款最新的芯片组经过上市数月的考验．证明完全能够承担起当前处理器高性能平台的重任。

简介：AIM:Toinvestigatethelifetimeriskofdevelopmentofesophagealadenocarcinomaand/orhigh-gradedysplasiainpatientsdiagnosedwithBarrett’sesophagus.METHODS:DatawereextractedfromtheUnitedKingdomNationalBarrett’sOesophagusRegistryondateofdiagnosis,patientageandgenderof7877patientsfromwhohadbeenregisteredfrom35UnitedKingdomcenters.LifeexpectancywasevaluatedfromUnitedKingdomNationalStatisticsdatabasedupongenderandageatyearatdiagnosis.Thesedatawerethenusedwithpublishedestimatesofannualadenocarcinomaandhigh-gradedysplasiaincidencesfrommetaanalysesandlargepopulation-basedstudiestoestimateoveralllifetimeriskofdevelopmentofthesestudyendpoints.RESULTS:ThemeanageatdiagnosisofBarrett’sesophaguswas61.6yearsinmalesand67.3yearsinfemales.Themeanlifeexpectancyatdiagnosiswas23.1yearsinmales,20.7yearsinfemalesand22.2yearsoverall.Usingdatafrompublishedmeta-analyses,thelifetimeriskofdevelopmentofadenocarcinomawasbetween1in8and1in14andthelifetimeriskofhigh-gradedysplasiaoradenocarcinomawas1in5to1in6.Usingdatafrom3largerecentpopulation-basedcohortstudiesthelifetimeriskofadenocarcinomawasbetween1in10and1in37andofthecombinedendpointofhigh-gradedysplasiaandadenocarcinomawasbetween1in8and1in20.AgeatBarrett’sesophagusdiagnosisisreducingandlifeexpectancyisincreasing,whichwillpartiallycounter-balancelowerannualcancerincidence.CONCLUSION:Thereisasignificantlifetimeriskofdevelopmentofhigh-gradedysplasiaandadenocarcinomainBarrett’sesophagus.

简介：Fluorescenceliftimeimaging(FLIM)ofmodifiedhydrophobicbodipydyesthatactasfluorescentmolecularrotorsshowsthatthefluorescencelifetimeoftheseprobesisafunctionofthemicroviscosityoftheirenvironment.Incubatingcellswiththesedyes,wefindapunctateandcontinuousdistributionofthedyeincells.Theviscosityvalueobtainedinwhatappearstobeendocytoticvesiclesinlivingcellsisaround100timeshigherthanthatofwaterandofcellularcytoplasm.Time-resolvedfluorescenceanisotropymeasurementsalsoyieldrotationalcorrelationtimesconsistentwithlargemicroviscosityvalues.Inthisway,wesuccessfullydevelopapracticalandversatileapproachtomapthemicroviscosityincellsbasedonimagingfluorescentmolecularrotors.

简介：Canearthquakesbepredicted?Howshouldpeopleovercomethedifficultiesencounteredinthestudyofearthquakeprediction?Thisissuecantakeinspirationfromtheexperiencesofweatherforecast.Althoughweatherforecastingtookaperiodofabouthalfacenturytoadvancefromempiricaltonumericalforecast,ithasachievedsignificantsuccess.AconsensushasbeenreachedamongtheChineseseismologicalcommunitythatearthquakepredictionmustalsodevelopfromempiricalforecastingtophysicalprediction.However,itisseldommentionedthatphysicalpredictionischaracterizedbyquantitativelynumericalpredictionsbasedonphysicallaws.Thisarticlediscussesfivekeycomponentsfornumericalearthquakepredictionandtheircurrentstatus.Weconcludethatnumericalearthquakepredictionshouldnowbeputontheplanningagendaanditsroadmapdesigned,seismicstationsshouldbedeployedandobservationsmadeaccordingtotheneedsofnumericalprediction,andtheoreticalresearchshouldbecarriedout.

简介：Inthispaper,weconsiderthenonsymmetricalhalf-planeprediction.Apredictiontheoreticproofofthefundamentalformulaaboutonesteppredictionerrorisgiven.AWold-typedecompositionanditsspectralrepresentationtheoremareproved.Spectralextractionproblemsofthehalf-planeinnova-tionsanditssingularcomponentsareinvestigated.

简介：用乳剂—溶剂挥发法制备硝苯地平的丙烯酸树脂缓释微球。微球中药物的释放速度随丙烯酸树脂ＥｕｄｒａｇｉｔＲＬ／ＲＳ比率的增加以及制备时搅拌速率的增加而增大，随内相聚合物浓度的增加及微球粒径的增加而减小，释药５０％所需时间与微球粒径呈良好线性。微球的释药速率也随药物含量的增加（从４．２％到１６．７％）而增大，并快于药物结晶的溶解速率，但药物含量达２６．６％时，微球释药速率明显下降并低于药物结晶的溶解速率。用差热分析和Ｘ射线衍射分析证明，药物含量为４．２，９．４和１６．７％的微球中药物完全是以非晶态分散的，而含药２６．６％的微球中有药物结晶存在。不同微球释药低于７０％时，释放方式均符合Ｈｉｇｕｃｈｉ时间平方根方程。

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简介：TheinfluenceoftemperatureandGacompositiononAugerrecombinationlifetimeinn-typeandp-typeIn1-xGaxAsmaterialsisinvestigatedthroughthesimulation,assumingtheconcentrationsofelectronsandholesare1017cm-3and1018cm-3,respectively.TheresultsshowthatthetemperaturehaslittleinfluenceonAugerrecombinationlifetimeofIn1-xGaxAsmaterialsatx<0.3.However,ithasagreatimpactwhenx>0.3andtheeffectismoreobviousatalowertemperature.Moreover,Augerrecombinationlifetimeofp-typeIn1-xGaxAsislongerthanthatofn-typeIn1-xGaxAswiththesametemperature,Gacompositionandcarriersconcentration.

简介：Thereisalargegapbetweenthenumberofmembraneprotein(MP)sequencesandthatoftheirdecoded3Dstructures,especiallyhigh-resolutionstructures,duetodifficultiesincrystalpreparationofMPs.However,detailedknowledgeofthe3DstructureisrequiredforthefundamentalunderstandingofthefunctionofanMPandtheinteractionsbetweentheproteinanditsinhibitorsoractivators.Inthispaper,somecomputationalapproachesthathavebeenusedtopredictMPstructuresarediscussedandcompared.

简介：Basedontheanalysisoftheaveragedaxisymmetricturbulentflowandthemotionandgrowthofgasnucleiintheflow,thispaperpresentsamethodforpredictingcavitationin-ceptioninpipelines.MathematicmodelisproposedandthefluctuatingpressureintheflowandotherrandomfactorswithrespecttogasnucleiaretreatedusingtheMonte-Carlomethod.Sothatthebridgebetweenmacroscopicaspectofcavitationintheflowandthemicroscopiceventofindividualnucleuscavitationissetup.Numericalinvestigationandexperimnentaltestarecarriedoutfortheflowpastanorificeinauniformpipewithcircularsection.