简介:BackgroundNoncompactionofventricularmyocardium(NVM)isararetypeofprimarycardiomyopathy.Thediseaseiscausedbythedisorderinthedensificationofthemyocardiumintheearlystageoftheembryoprocess.Themorphologicalcharacteristicsareprojectingtrabeculationintheventricleandthedeeptrabecularspaceinterlinkedwithventricularchamber.Inrecentyears,manystudieshavefoundthattheleftventriculargrowthassociatedgeneticmutationiscloselyrelatedtotheoccurrenceofNVM.Themostclinicalmanifestationssuchasheartfailure,thromboembolismandarrhythmiaarespecific.EchocardiographyisthemostcommonlyusedtechniqueforthediagnosisofNVM.Cardiaccomputedtomography(CT)scan,cardiacmagneticresonanceimagingandleftventricularangiographyareotherimportanttechniquesforitsdiagnosis.TheNVMpatientshavealongcourseofdisease,poorprognosisandahighrateofmisdiagnosis.Thisarticlereviewstheresearchprogressintheaspectsofepidemiologicalcharacteristics,geneticcharacteristics,clinicalmanifestations,pathophysiology,diagnosis,treatmentandsoon,inordertoprovidethebasisforthediagnosisandtreatmentofNVM.
简介:1920sAmericaembracedanageofprosperityandliberation.Economysoaredthatraisedpeople'slivingstandard.Peoplelearnprogressiveideas,andsocietybecomemoredemocratic.
简介:BackgroundMyocardialfibrosisisoneprocessofthevariousheartdiseases,whichleadstocommonpathologicalchangeswhenitdevelopstoacertainstage.Itisthemaincauseofventricularremodelingwhicheventuallyleadstodifferentdegreesofcardiacdysfunction,malignantarrhythmiasandsuddencardiacdeath.Manystudieshaveshownthatvariouscytokinesplayaveryimportantroleinthedevelopmentofmyocardialfibrosis.Thispaperreviewsthelatestresearchesontheroleofcytokinesinmyocardialfibrosis.
简介:Occlusaldisordercausedbysevereworndentitionisoneofthemostcommondiseasesintheocclusion.Occlusalreconstructionisanimportantrepairmethod,referringtomodifyandrebuildtheexistingocclusionstatus,thentorestoretheocclusion.Duringocclusalreconstruction,thedigitalocclusionanalysissystemcanaccuratelyacquiretheocclusionstatus,inordertoguidethereconstructionocclusionaccuratelyandrestorethenormalfunctionoftheoralmaxillarysystem.Thispaperreviewstheconceptofocclusalreconstruction,sequencetherapy,traditionalocclusionanalysismethodsandthedevelopmentstatusandprospectofdigitalocclusionanalysis.
简介:Sincethe18thNationalCongressoftheCommunistPartyofChina,GeneralSecretaryXiJinpinghasissuedaseriesofimportantexpositionsonpeaceanddevelopment,whoseimpactisincreasinglyimportantforthecurrentprocessofglobalgovernance.XihaspointedoutthatChinesecivilizationhasupheldharmonyinhandling
简介:Thedevelopmentofcancernanotherapeuticshasattractedgreatinterestintherecentdecade.Cancernanotherapeuticshaveovercomeseverallimitationsofconventionaltherapies,suchasnonspecificbiodistribution,poorwatersolubility,andlimitedbioavailability.Nanoparticleswithtunedsizeandsurfacecharacteristicsarethekeycomponentsofnanotherapeutics,andaredesignedtopassivelyoractivelydeliveranti-cancerdrugstotumorcells.Weprovideanoverviewofnanoparticle-baseddrugdeliverymethodsandcancertherapiesbasedontumor-targetingdeliverystrategiesthathavebeendevelopedinrecentyears.
简介:TheBe-basedmaterialswithmanyparticularpropertiesleadtoanimportantresearchsubject.Theinvestigationprogressesinthefabricationtechnologiesareintroducedhere,includingmainthreekindsofBe-basedmaterials,suchasBe–Cucapsule,Be_2Cablatorandhigh-purityBematerial.ComparedwiththepioneerworkgrouponBe-basedmaterials,thedifferencesinBe–Cutargetfabricationweredescribed,andagrainrefinementtechniquebyanactivehydrogenreactionforBecoatingwasproposeduniquely.Be_2CcoatingswerefirstpreparedbytheDCreactivemagnetronsputteringwithahighdepositionrate(~300nm/h).PurepolycrystallineBe_2Cfilmswithuniformmicrostructures,smoothsurface,highdensity(~2.2g·cm~3)andgoodopticaltransparencywerefabricated.Inaddition,thehigh-purityBematerialswithmetalimpuritiesinappmmagnitudewerefabricatedbythepyrolysisoforganometallicBe.
简介:在在参考书在中等Mn钢上总结相关研究以后,张力的性质上的二个新目标被定义。一个人两个都是那导致转变(旅行)并且导致双胞胎的粘性(缇)能与一个相对低的Mn内容为钢被认识到,它与更高的Mn内容展出类似的张力的性质到古典缇钢。其它将完成超离频的最终的张力的力量(>1.5?GPa)没有牺牲formability。达到这些目标,新设计策略为作文和处理线路被提出。特别地,因为前者能经由部分再结晶与不同形态学和尺寸生产保留的奥氏体谷物的混合物,温暖的滚动被采用而不是平常的热/冷的滚动过程。因而,保留的奥氏体谷物有大量技工稳定性以便他们能在变丑期间逐渐地转变到马氏体,导致提高的旅行效果然后改进技工性质。最后,它在在实验室生产这些指向的中等Mn钢被接替,他们中的一些甚至比我们的期望展出更好张力的性质。