简介:ObjectivesTotestthefeasibilityoftheuseofhighthoracicepiduralanesthesiaasasoleanestheticinpatientsundergoingoffpumpcoronaryarterybypasssurgery,avoidinggeneralanesthesia.MethodsBetweenOctober2002toApril2003,twentyfivecasesunderwentbeatingheartcoronaryarteryrevascularizationwithoutendotrachealgeneralanesthesia,usinghighthoracicepiduralanesthesiaandanalgesia.Allthepatientsunderwentepiduralcatheterizationontheeveningbeforethesurgery.ResuitsThepatientsinallreceived71grafts(singlen=11,doublen=5,triplen=6,quadruplen=3).Sixpatientsunderwentrepeatcoronaryarterybypass.Exceptonewasconvertedtogeneralanesthesiaandcardiopulmonarybypass,theotherpatientsunderwentoff-pumpcoronaryarterybypassgraftsurgery,2patientsunderwentgraftingvialeftthoracotomy(MIDCAB)andtherestthroughmidsternotomy.Therewasnomortality.Meanlengthofstayintheintensivecareunitwas16.2(4.2hoursandhospitalwas3.0(1.2days.ConclusionsOurexperienceconfirmsthefeasibilityofperformingmuhiplecoronaryarterybypassesinconsciouspatientswithoutendotrachealgeneralanesthesia.
简介:ObjectivesToevaluateretrospectivelythepotentialbenefitsofcombinedutilizationofvariousassistedcirculationdevicesincardiacarrestpatientswhodidnotrespondtoconventionalcardiopulmonarycerebralresuscitation(CPCR).MethodsAssistedcirculationdevices,includingemergencycardiopulmonarybypass(ECPB),intra-aorticballoonpump(IABP),andleftventricularassistdevice(LVAD),wereappliedto16adultpatientswhohadcardiacarrest82min-56hafteropenheartsurgeryanddidnotrespondto20minorlongerconventionalCPCR.ECPBwasappliedto2patients,ECPBplusIABPto8patients,ECPBplusIABPandLVADto6patients.ResultsOnepatientrecoveredfullyandonepatientdied.Oftheother14patients,13resumedspontaneouscardiacrhythmandonedidnot;noneofthemcouldbeweanedfromECPB.Furthertreatmentofthe14patientswithcombinationsofassistedcirculationdevicesenabled6patientstorecover.Oneofthe7recoveredpatientsdiedofreoccurringcardiacarrestafter11days;theother6weredischargedingoodconditionandwerefollowedupfor3-49months(mean=22months).Ofthe6dischargedpatientsonesufferedcerebralembolismduringLVADtreatment,resultinginmildlimitationofmobilityoftherightlimbs;theother5nevermanifestedanycentralnervoussystemcomplications.Therewasnolatedeathsgivinga37.5%(6/16)long-termsurvivalrate.ConclusionsECPBcouldeffectivelyreestablishbloodcirculationandoxygensupply,rectifyacidosis,andimproveinternalmilieu.ThecombinedutilizationofECPB,IABP,andLVADreducesthedurationofECPB,improvestheincidenceofrecovery,andoffersbeneficialalternativestorefractorycardiacarrestpatients.
简介:Objective:Tocomparativelystudythedifferenteffectsofopenheartsurgeryonbraintissuesofpatientswithcongenitalandrheumaticheartdisease.Methods:Fortypatientswithcongenitalheartdisease(CHD,CHDgroup,n=20)orrheumaticheartdisease(RHD,RHDgroup,n=20)underwenton-pump(cardiopulmonarybypass,CPB)heart-beatingopenheartsurgery.BloodsamplesbeforeCPB,and20minutes,1hour,24hoursand7daysafterCPBwerecollected,andthelevelsofneuron-specificenolase(NSE)andproteinS-100bintheplasmaweredeterminedwithenzyme-linkedimmunoadsorbentassay(ELISA),respectively.Allthepatientswereexaminedwithelectroencephalogram(EEG)beforeand1weekafteroperation.ThechangesofNSE,S-100bandEEGcomparedtoverifythedifferenceofpostoperativecerebralinjurybetweenCHDcasesandRHDcases.Results:TheplasmalevelofS-100bincreasedsignificantly20minutesafterCPBandwasstillhigherthanthepreoperativelevelat24hoursafteroperationinbothgroups(P<0.01).TheplasmalevelofNSEincreasedmoresignificantlyintheCHDgroupthanintheRHDgroup20minutesafterCPBanditreturnedtothenormallevel24hoursafterCPBintheCHDgroupbutremainedatahighlevelintheRHDgroup(P<0.01).ThelevelsofNSEandS-100breturnedtothenormallevelsonthe7thdayafterCPB.AbnormalEEGwasfoundin75%ofthepatientsintheCHDgroupand60%intheRHDgroup.Conclusions:On-pumpheart-beatingopenheartsurgerycancausecertaincerebralinjuryinthepatientswithCHDorRHD.TheinjurywasmoresevereandrecoveredmorequicklyintheCHDgroupthanintheRHDgroup.
简介:Coronaryarterybypassgrafting(CABG)isenteringaneweraasminimallyinvasivetechniques,off-pumpsurgeryandtotal'arterialrevascularizationhavefotmdrolesinthesurgicaltreatmentofpatientswithcoronaryarterydisease.Thecontinueddevelopmentofthetechniquesofpercutaneouscoronaryintervention(PCI)isalsohavinganimpactonthetypeofpatientreferredforCABG.
简介:静脉的thromboembolism(VTE)作为深静脉血栓(DVT)和肺的栓塞(PE)被表明,代表死亡,残疾,和不快的一个重要原因。他们是各种各样的外科的过程的经常的复杂并发症。变老的人口和更严重地受伤的病人的幸存可以在损伤病人建议thromboembolism的增加的风险。在风险挑战医生扩展了人口的理解小心地检验风险因素让VTE识别能得益于预防的高风险的病人。基于证据的风险因素的精确知识在预言并且阻止手术后的DVT是重要的,并且能为appropriatethromboprophylaxis使用被合并到一个决定支持系统。在一张高风险的损伤人口的DVT预防的标准使用在下导致DVT的发生。VTE的发生在亚洲是普通的。评估包括实验室测试,Doppler测试和phlebography。屏蔽Dopplersonography应该在所有非常受伤的病人上为监视被执行识别DVT。D暗淡是一个有用标记在损伤外科病人监视预防。开始预防的最佳的调子以前在2hours之间并且在外科以后的10个小时,而是PE的风险继续因为几weeks.Thromboprophylaxis为预防包括毕业压缩袜子和抗凝剂。抗凝剂包括Warfarin,它属于维生素K对手,unfractionatedheparin,低分子的重量肝磷脂,因素Xa间接禁止者Fondaparinux,和口头的IIainhibitorMelagatran和ximelagatran。Recombinant人的solublethrombomodulin是一个新、高度有效的antithrombotic代理人。在选择损伤病人的venacaval过滤器的预防放置可以减少PE的发生。为预防劣等的静脉cava过滤器插入的指示与多重损害,关上的头损害,骨盆的破裂,脊骨破裂,多重长骨头破裂,和出席谨慎包括延长固定。多重损伤的病人在为DVT的增加的风险,但是也在流血,和肝磷脂的使用的增加的风险可以被禁忌。连续压缩设备(SCD)是为DVT预防的一种选择。压缩设备向足够的DVTprophylaxis提供低失败率和没有设�
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简介:Treated50casesofrenalcolicwithelectroacupunctureandcomparedtheresultswiththoseintwocontrolgroups.Totaleffectiverateinthetreatmentgroup,controlgroupⅠandcontrolgroupⅡwas98.0%,90.0%and92.0%respectively.
简介:Objective:Toinvestigatethedepressionstatusofpatientswithsexuallytransmitteddiseases(STDs).Methods:Thedepressionstatusoffifty-onehospitalizedSTDpatientswasevaluatedinarandomizedcontrolstudyusingZung'sQuantitativeTable.18healthycontrolpatientswithsimilardemographicbackgroundswererandomlychosenascontrols.Patientswithscoresaboveorequalto40wereconsideredtobesufferingfromdepression.Results:Theprevalencerateofdepressioninthepatientgroupwasobviouslyhigherthanthatofinthecontrol(X2=16.456,P<0.01).Prevalenceofdepressionwasfoundtobesignificantlyrelatedtooccupation(P<0.05).Thoughtheprevalencewasnotfoundtodiffersignificantlybetweenthosewithatreatmentcourselessthan2monthsandthosewithonelongerorequalto2months(X2=0.041,P>0.05),themeandepressionscoresoftheformergroupweresignificantlyhigherthanthoseofthelatter(P<0.01).Nosignificantdifferenceswerefoundbetweennewversusrelapsingdisease,marriedversusnon-married,maleversusfemale,ordifferingeducationalbackgrounds.
简介:Aims:Toinvestigatetheinfluenceofacupunctureoninsulinresistanceinobesitypatients.Methods:Intreatmentgroup,20obesitypatientsweretreatedwithacupunctureofNeiguan(PC6),Zusanli(ST36),Daimai(GB26),Sanyinjiao(SP6),Zhongwan(CV12),etc..Incontrolgroup,12normalvolunteersubjectswereobserved.Theobesityindex,fastingbloodsugar(FPG),plasmainsulin(FINS)andC-peptidecontents,andinsulinsensitiveindex(ISI)weremeasuredbeforeandafteracupuncturetreatment.Results:Beforetreatmentincomparisonwithcontrolgroup,FPG,FINSandC-peptideofobesitypatientsweresignificanthigher(P<0.01),whileISIwasconsiderablylower(P<0.01);afteracupuncturetreatment,thelevelsofplasmainsulinandCpeptidedecreasedobviously,ISIincreasedmarkedly(P<0.01),andtheobesityindexwasconsiderablyimprovedwithatotaleffectiverateof85%.Conclusion:Acupuncturecanalleviateobesityandimproveinsulinresistance.
简介:ThisarticlepresentstheepidemiologicalsurveyofthepatientsatthedispensaryoftheBeijingCapitalAirportfromJuly,1991toJune,1992.Theconstituentratiosofdiseaseandagewereanalyzed.TheresultsofthisstudymaybeprovedhelpfultotheemergencytreatmentatcertainAirports.
简介:Comparedwithhighinfectionareasoftheworld,thetotalHIVinfectionrateinChinaisrelativelylow.Nonetheless,becauseofChina'svastterritoryandlargepopulation,thepotentialinfectionriskmustbetakenseriously.Inthenextfewyears,needlesharingamonginjectiondruguserswillremainthemostcommonrouteoftransmissionfortheHIV/AIDSepidemicinChina.Unprotectedsexisgraduallybecomingamajorrouteoftransmission.ChinabegantoimplementHAARTin1999accordingtointernationalstandards.Priorto2003,therewereonlyabout150HIV/AIDSpatientsweretreatedwithHAARTinsomeclinicaltrialsandabout100HIV/AIDSpatientsweretreatedbyprivatesources.ResultsofthosetreatmentsarethescientificbasisfordevelopmentofthetherapeuticstrategiesinChina.InMarchof2003,theChinesegovernmentinitiatedChinaCARESprogram.InNovemberof2003,theChineseMinistryofHealthannouncedanationalpolicyoffreeARVtreatmenttoallHIV+ChinesecitizenswhowereinpovertyandrequiredARVtherapy.Therearetotalof19,456HIV/AIDSpatientsreceivedfreeARVdrugstodatein159regionsand441towns.Currentchallengesarehowtofollow-upandevaluatethosepatientsintheclinicalsettings.Thelongerthetherapyispostponed,themoresideeffectsandthehigherprobabilityofdrugresistancearegoingtooccur.Itremainsunclear,therefore,whenHAARTregimenshouldbestartedintheHIV/AIDSpopulationinChina.
简介:ObjectiveToinvestigatetheeffectoffamilytherapyonprognosisofpatientswithschizophrenis.Method200patientsafterdischargingfromhospitalwererandomlydividedintotwogroups:controlgroup(n=100)andexperimentgroup(n=100).Familytherapywasactualizedinpatientsofexperimentgroup.ResultsTherewassignificantdifferenceinpercentofrecurrenceratebetweencontrolgroup(38%)andexperimentgroup(18%,P<0.05).ConclusionFamilytherapymaydecreaserecurrencerateofschizophrenicafterdischargingfromhospital.
简介:AIM:Tounderstandthecorrelationofserumcholinesterase(CHE)activitywithgastriccancerandtoassesstheirclinicalsignificance.METHODS:ThevelocitymethodwasadoptedtodetecttheactivityofserumCHEinpatientswithgastriccancerandinpatientswithnon-malignanttumorascontrols.RESULTS:TheserumCHEactivityinthetreatmentgroupwassignificantlylowerthanthatinthecontrolgroupwithaverysignificantdifferencebetweenthetwogroups(83.3:113.1,P=0.0003).Agewassignificantlyassociatedwiththeincidenceofgastriccaner.CONCLUSION:SerumCHEactivityhasacloserelationwiththeincidenceofgastriccancer.