简介：Basedontheexistingcontinuousboreholestrainobservation,themultiquadricfunctionfittingmethodwasusedtodealwithtimeseriesdata.Theimpactofdifferencekernelfunctionparameterswasdiscussedtoobtainavaluablefittingresult,fromwhichthephysicalconnotationoftheoriginaldataanditspossibleapplicationswereanalyzed.Meanwhile,abriefcomparisonwasmadebetweentheresultsofmultiquadricfunctionfittingandpolynomialfitting.

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简介：ThispaperpresentsacontrolLyapunovfunctionapproachtotheglobalstabilizationproblemforgeneralnonlinearandtime-varyingsystems.ExplicitstabilizingfeedbackcontrollawsareproposedbasedonthemethodofcontrolLyapunovfunctionsandSontag'suniversalformula.

简介：Ｅｍｉｓｓｉｏｎ　Ｔｅｍｐｅｒａｔｕｒｅｓ　ｆｒｏｍ　Ｐｏｐｕｌａｔｉｏｎｓ　ｏｆ　Ｐａｒｔｉｃｌｅ　Ｕｎｓｔａｂｌｅ　Ｓｔａｔｅｓ　ａｓ　ａ　Ｆｕｎｃｔｉｏｎ　ｏｆ　Ｉｍｐａｃｔ　ＰａｒａｍｅｔｅｒＥｍｉｓｓｉｏｎＴｅｍｐｅｒａｔｕｒｅｓｆｒｏｍＰ...

简介：AnovelnumericalmodelbasedontheimageGreenfunctionandfirst-orderTaylorexpansionboundaryelementmethod(TEBEM),whichcanimprovetheaccuracyofthehydrodynamicsimulationforthenon-smoothbody,wasdevelopedtocalculatethesidewalleffectsonfirst-ordermotionresponsesandsecond-orderdriftloadsuponoffshorestructuresinthewavetank.Thismodelwasconfirmedbycomparingittotheresultsfromexperimentsonhydrodynamiccoefficients,namelythefirst-ordermotionresponseandsecond-orderdriftloaduponahemisphere,prolatespheroid,andbox-shapedbargeinthewavetank.Then,thehydrodynamicsoftheKVLCC2modelwerealsocalculatedintwowavetankswithdifferentwidths.Itwasconcludedthatthismodelcanpredictthehydrodynamicsforoffshorestructureseffectively,andthesidewallhasasignificantimpactonthefirstorderquantitiesandsecond-orderdriftloads,whichsatisfiedtheresonantrule.

简介：ObjectiveTostudytheeffectofsalicylateontheexpressionandfunctionofNMDAreceptorsinspiralganglionneurons(SGNs).MethodsThemRNAofNR1subunitofNMDAreceptorinmodiolustissuesweredetectedbyRealtimefluorescencequantitativePCR(FQ-PCR).NMDAreceptorwhole-cellcurrentswererecordedusingpatchclampinacuteisolatedSGNs.ResultsComparedwiththecontrolgroup,salicylatesignificantlyincreasedthemRNAlevelofNR1subunitinSGNs.NMDAofconcentrationsrangingfrom0.1mMto10mMevokednocurrentinSGNs.NMDA(0.1mMand0.5mM)appliedwithsalicylate(5mM),however,inducedinwardcurrents(212.6±15.2pA,n=5;607.9±44.3pA,n=5)inadose-dependentmanner,whichcouldbeinhibitedbyAPV.SalicylatealonedidnotproduceanycurrentinSGNs.ConclusionSalicylateincreasestheexpressionofNMDAreceptorsandfacilitatesthecurrentsmediatedbyNMDAreceptorsinSGNs.

简介：Anovelrepetitivecontrolstrategyfortheoutputwaveformofsingle-phaseCVCFinvertersispresented.Inthisscheme,theinversetransferfunctionofinverterisusedasacompensatortoobtainstableandsatisfyharmonicrejection.Besides,PDcontrollerisadoptedtoimprovetransientperformance.Simulationandexperimentalresults,whicharegottenfromaDSP-based400Hz,5.5KWinverter,indicatethattheproposedcontrolschemecanachievenotonlylowTHDduringsteady-stateoperationbutalsofasttransientresponseduringloadstepchange.

简介：ThepaperisacontributiontotheproblemofapproximatingrandomsetwithvaluesinaseparableBanachspace.Thisclassofset-valuedfunctioniswidelyusedinmanyareas.Weinvestigatethepropertiesofp-boundedintegrablerandomset.Basedonthisweendowitwith△pmetricwhichcanbeviewedasaintegraltypehausdorffmetricandpresentsomeapproximationtheoremofaclassofconvolutionoperatorswithrespectto△pmetric.Moreoverwealsocanestablishanalogoustheoremforotherintegraltypeoperatorin△pspace.

简介：Itisveryimportantinthefieldofbioinformaticstoapplycomputertoperformthefunctionannotationfornewsequencedbio-sequences.BasedonGOdatabaseandBLASTprogram,anovelmethodforthefunctionannotationofnewbiologicalsequencesispresentedbyusingthevariable-precisionroughsettheory.TheproposedmethodisappliedtotherealdatainGOdatabasetoexamineitseffectiveness.Numericalresultsshowthattheproposedmethodhasbetterprecision,recall-rateandharmonicmeanvaluecomparedwithexistingmethods.

简介：Background:Physicalactivity(PA)hasbeenshowntobenefitcognitivefunctioninolderadults.However,thecognitivebenefitsofexercisingforolderChineseadultshavenotbeensystematicallydocumented.ThisstudywastoconductasystematicreviewonevidencethatPAisbeneficialforcognitivefunctioninginolderChineseadults.Methods:Majordatabases,includingPubMed,EMBASE,CochraneLibrary,WanFang,CNKI,andVIP,weresearchedforstudiespublishedinEnglishorChinesebetweenJanuary2000andDecember2015.Randomizedandnon-randomizedcontrolledtrials(RCTsandnon-RCTs),cohort,case-controlandcross-sectionalstudiesthatevaluatedPAandcognitivefunctionamongolderChineseadultswereincludedinthisreview.Results:Of53studiesincludedandreviewed,33wereobservational(22cross-sectional,7case-control,and4cohort)and20wereexperimental(15RCTs,5non-RCTs).Observationalstudiesshowedanassociationofreducedriskofcognitive-relateddiseases(i.e.,mildcognitiveimpairment,Alzheimer’sdisease,anddementia)throughPA,whereasexperimentalstudiesreportedexercise-inducedimprovementinmultipledomainsofcognitivefunction(i.e.,globalcognitivefunction,memory,executivefunction,attention,language,andprocessingrecourse).Conclusion:ThissystematicreviewprovidesinitialevidencethatPAmaybenefitcognitioninolderChineseadults.FurtherstudiesofindividualswithcognitiveimpairmentsandprospectiveandRCTstudieshavinghighscientificrigorareneededtocorroboratethefindingsreportedinthisreview.

简介：蛋白质的表示得到或从Magnaporthe，在在米饭(OryzasativaL)激活抵抗的griesea和它的生物功能被报导。基因ofelicitor在Escherichia关口i房间被表示并且在SDS页上与42kDapparent分子量生产了His_6熔化蛋白质。净化的蛋白质能分别地导致抵抗到强风疾病，与在在强风接种以后的第14天和第21天的46.47%和36.41%的控制效率。同时，在有表示蛋白质，phenylalanineammonia-lyase(PAL)和过氧化物酶(邮政部门)的处理以后，活动在米饭植物被支持STKM，一度时髦的风尚，PBZ1和PR1基因的抄写层次在米饭植物被增加。而且在在二维的电气泳动胶化上比较全部的米饭叶蛋白质的侧面以后，大约14proteins被发现在表示蛋白质处理以后在表示水平被增加。Allthe结果显示表示蛋白质能是行动一elicit或在米饭触发抵抗。

简介：Abinaural-loudness-model-basedmethodforevaluatingthespatialdiscriminationthresholdofmagnitudesofhead-relatedtransferfunction(HRTF)isproposed.Astheinputofthebinauralloudnessmodel,theHRTFmagnitudevariationscausedbyspatialpositionvariationswerefirstlycalculatedfromahigh-resolutionHRTFdataset.Then,threeperceptualrelevantparameters,namelyinterauralloudnessleveldifference,binauralloudnesslevelspectra,andtotalbinauralloudnesslevel,werederivedfromthebinauralloudnessmodel.Finally,thespatialdiscriminationthresholdsofHRTFmagnitudewereevaluatedaccordingtojust-noticedifferenceoftheabove-mentionedperceptual-relevantparameters.AseriesofpsychoacousticexperimentswasalsoconductedtoobtainthespatialdiscriminationthresholdofHRTFmagnitudes.Resultsindicatethatthethresholdderivedfromtheproposedbinaural-loudness-modelbasedmethodisconsistentwiththatobtainedfromthetraditionalpsychoacousticexperiment,validatingtheeffectivenessoftheproposedmethod.

简介：摘要：s-function是一种描述动态系统的计算机语言，支持C语言编写，可以将已有的软件代码用文本方式输入，实现了代码移植和验证，非常适合复杂动态系统的数学描述，并且在仿真过程中可以对仿真进行更精确的控制。目前，实际风电变流器产品中，每台产品都需要在出厂时，都需要经过严格的测试，随着对产品不同功能的需求变化，采用的测试软件需要不断的优化和改进，所以，对软件算法的验证和升级需要仿真给予可靠的支持。本文利用在Simulink中搭建的三相全桥逆变器模型与S-Function编写的算法模块相结合，针对并网整流器运行工况进行软件仿真，简单、有效地验证了测试软件算法的正确性。

简介：Toinvestigatetheprotectiveeffectofepigallocatechingallate(EGCG)ontheimmunefunc-tionofdendriticcells(DCs)afterultravioletBirradiation(UVB)anditsunderlyingmechanisms,themonocyteswereisolatedfromperipheralbloodandcultivatedintoDCswithcytokines,suchasGM-CSFandIL-4.DCswereharvestedaftercultivationfor7dandsubjectedtoirradiationwithdifferentdosagesofUVB.Then,200μg/mlofEGCGwereaddedincertaingroupsimmediatelyafterirradiation.DCssimplytreatedwithUVBortreatedwithbothUVBandEGCGwereco-culturedwithlymphocytes,andMTFassaywasusedtodetecttheabilityofDCstostimulateproliferationoflymphocytes.SurfacemarkersCDS0,CD86,HLA-DRandCD40weredetectedbyflowcytometry,andthelevelsofIL-10andIL-12secretedfromDCs24haftercultivationweremeasuredbyELISA.ItwasdemonstratedthatUVBirradiationcouldinhibittheabilityofDCstostimulatetheproliferationoflymphocytesandsurfaceexpressionsofCDS0,CD86,HLA-DRandCD4onDCsinadose-dependentmanner.TheinhibitionrateofDCswasimprovedtosomeextentaftertreatmentwith200μg/mlofEGCG.Whentheconcentra-tionofEGCGexceeded100μg/ml,theenhancingeffectofEGCGontheexpressionoftheco-stimulat-ingmoleculesonDCscouldbedemonstratedinadose-dependentmanner.UVBshowednosignificantinfluenceonthesecretionofIL-10andIL-12fromDCs,whileEGCGcoulddown-regulatethesecretionlevelofIL-12andup-regulatethatofIL-10.ItisconcludedthatEGCGcanantagonizetheinhibitoryeffectonDCsinducedbyUVBirradiation.Thisfunctionhassomerelationshipwithitsprotectingeffectoftheexpressionoftheco-stimulatingmoleculeonthesurfaceofDCsandthesecretionlevelofIL-10andIL-12.

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简介：Compactlysupportedradialbasisfunctioncanenablethecoefficientmatrixofsolvingweighlinearsystemtohaveasparsebandedstructure,therebyreducingthecomplexityofthealgorithm.Firstly,basedonthecompactlysupportedradialbasisfunction,thepapermakesthecomplexquadraticfunction(Multiquadric,MQforshort)tobetransformedandproposesaclassofcompactlysupportedMQfunction.Secondly,thepaperdescribesamethodthatinterpolatesdiscretemotioncapturedatatosolvethemotionvectorsoftheinterpolationpointsandtheyareusedinfacialexpressionreconstruction.Finally,accordingtothischaracteristicoftheunevendistributionofthefacemarkers,themarkersarenumberedandgroupedinaccordancewiththedensitylevel,andthenbeinterpolatedinlinewitheachgroup.Theapproachnotonlyensurestheaccuracyofthedeformationoffacelocalareaandsmoothness,butalsoreducesthetimecomplexityofcomputing.

简介：AbstractSkeletal muscle plays an essential role in generating the mechanical force necessary to support the movement of our body and daily exercise. Compared with cardiac and smooth muscle, in mammals, skeletal muscle exhibits remarkable regenerative capacity in response to damage. Muscle stem cells, also known as satellite cells, directly contribute to regeneration. Here, we review primary and secondary myogenesis processes with a focus on muscle stem cells, as well as the function and regulation of muscle stem cells in adult muscle regeneration in mammals.

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简介：InthisarticleweintroducethedifferencesequencespacesW0[f,Δm],W1[f,Δm],W∞[f,Δm]andS[f,Δm],definedbyamodulusfunctionf.WeobtainarelationbetweenW1[f,Δm]∩l∞[f,Δm]andS[f,Δm]∩l∞[f,Δm]andprovesomeinclusionresults.

简介：AbstractBackground:The relationship of uric acid (UA) with the thyroid function among healthy individuals remains unclear. We aimed to examine the relationship between UA contents and thyroid hormone levels in healthy Chinese individuals.Methods:This was a cross-sectional study of 1186 Chinese adults (736 men and 450 women) who underwent a health check-up at the Huadong Hospital Affiliated to Fudan University (Shanghai, China) between January 1, 2010 and July 31, 2018. Clinical and thyroid hormone levels were compared in different UA groups (in male and menopause women groups, MG1: UA < 5 mg/dL; MG2: 5 mg/dL ≤ UA< 7 mg/dL; and MG3: UA ≥ 7 mg/dL; in female groups, FG1 to FG3 represent the UA levels of <4 mg/dL, 4 mg/dL ≤ UA< 6 mg/dL, and ≥6 mg/dL, respectively). In addition, natural cubic spline regression, together with Pearson correlation analysis, was performed in investigating the correlation of UA with thyroid hormones.Results:After adjusting for confounding factors, low levels of UA (for males, UA < 5.30 mg/dL; for females, UA < 4.05 mg/dL) were negatively correlated with free triiodothyronine (FT3) both in men and women. UA levels between 4.83 and 6.06 mg/dL may act to protect FT3 in women, while UA levels between 6.39 and 7.09 mg/dL may protect FT3 in men. FT3 levels of low-range UA group reduced compared with mid-range UA and the high-range UA groups in both men and women.Conclusions:Our results provide epidemiologic evidence to support the negative correlation between low UA contents and FT3 in the Chinese Han population, suggesting that the reduced UA contents may serve as the risk factor to predict poor thyroid function in Chinese individuals.