简介：【摘要】目的 探析鼠神经生长因子在脑梗死治疗中的应用效果及其对血浆D-D、TXB2和BNP的影响。方法 随机选取本院68例脑梗死患者，时间选自2019年4月-2020年12月，随机分组，对照组（n=34）与观察组（n=34）分别实施常规治疗与常规治疗结合鼠神经生长因子治疗，对比两组治疗效果。结果 血浆BNP、TXB2和血浆D-D方面，观察组比对照组低，差异显著（P

简介：【摘要】目的  探讨他克莫司软膏治疗皮炎湿疹的疗效及对外周血Th1、Th2细胞因子水平的影响。方法  从收治的湿疹患者中选取72例作为研究对象，随机分组，各36例。其中对照组以糠酸莫米松软膏治疗，观察组以他克莫司软膏治疗。比较治疗疗效、不良反应。结果  观察组治疗总有效率高于对照组，差异显著（p＜0.05）。治疗后观察组Th1、Th2细胞因子指标水平优于对照组，差异显著（p＜0.05）。观察组不良反应发生率低于对照组，差异显著（p＜0.05）。结论  他克莫司软膏治疗皮炎湿疹的效果令人满意，可有效调节Th1/Th2细胞因子的平衡，并且具有较高的安全性。

简介：【摘要】：目的：探讨联合应用复方益母草膏与屈螺酮炔雌醇片对药物流产后患者免疫功能以及炎性因子水平的影响。方法：选取我院妇产科 2017 年 8 月 - 2018 年 7 月收治的 124 例 行药物流产患者为研究对象，将其随机分为例数相等的两组：观察组和对照组，每组 62 例 。对照组在胎囊排出后服用屈螺酮炔雌醇片，观察组在胎囊排出后服用屈螺酮炔雌醇片联合复方益母草膏。观察比较治疗前后两组患者血清肿瘤坏死因子 α（ TNF-α）、 γ干扰素（ IFN-γ）、白细胞介素 6 （ IL-6 ）、 IL-10水平。结果： 两组患者治疗后的

简介：　　 [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月～ 2020年 1月我院收治的溃疡性结肠炎患者 80例，随机分为两组，每组各 40例，两组患者均予常规对症治疗，同时两组均予美沙拉嗪缓释颗粒，观察组同时加用双歧三联活菌胶囊，治疗后比较两组患者治疗后的临床疗效，以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%，显著高于对照组的总有效率 70.00%，两组疗效比较差异具有显著性（ P<0.05）。治疗后，两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低（ P<0.05）。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组（ P<0.05）。观察组患者治疗后的临床症状积分为（ 2.56±0.85）分，与治疗前及对照组比较，差异有统计学意义（ P<0.05）。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切，且可以抑制炎症反应，值得临床推广和应用。  　　 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子  　 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.