简介:ANEWCERAMIDEFROMTHEMARINESPONGEBIEMNASP.¥ZhiZERG;LongMeiZENG;JingYuSU(DepartmentofChemistry,ZhongshanUniversity,Guangzhou,610...
简介:Marineorganismsaretheimportantsourceofthebioactivemetabolites.Anovelenolicsulfatedsterol,arenicolsterolA,hasbeenisolatedfromamarineannelidArenicolacristatacollectedinthecoastofMainlandofChina.ThestructurewaselucidatedusingallsortsofspectroscopicdataincludingESIMS,1Dand2DNMRetc.ThecytotoxicbioactivityofthissterolwasevaluatedbyMTTassay.Itcouldinhibitthegrowthofhumancervixcancercellline(Hela)andhumannon-smallcelllungcancercellline(NCI-h6)withIC50of(3.1+0.6)μg/mLand(7.6+0.8)μg/mL.