简介：瞄准：为了评估胰腺的织物的组织学的评估的诊断精确性，一个修改方法为恢复并且处理内视镜的超声(EUS)获得的样品指导了好针渴望(FNA)在胰腺的固体的鉴别诊断的材料集中。方法：有胰腺的群众的62个连续病人有希望地被学习。EUS被线性扫描PentaxFG-38UX回响内诊镜执行。三FNA(22G针)在每个过程期间被执行。与第一和第二根刺获得的材料为cytological学习被处理。第三根刺的材料被盐溶液的小心的注射通过针为摩尔答案恢复进10%，并且为组织学的学习处理了。结果：一些为组织学的分析获得的核心标本是6.5+/-5.3公里(范围1-22公里)。Cytological和组织学的样品在51被看作足够(82.3%)并且52个盒子(83.9%)分别地。为恶意的诊断的胰腺的细胞学和组织学的全面敏感是68.4%。与细胞学相反，组织学能诊断除煽动性的群众的腺癌，和所有情况以外的瘤。细胞学和组织学的联合允许在56种情况(90.3%)中获得一件足够的样品，与84.21%的全球敏感，100%的特性和90.32%的全面精确性。复杂并发症率是1.6%。结论：为组织学的检查的足够的胰腺的核心标本能被指导EUS的FNA获得。这种技术为胰腺的瘤的不同类型和良性的疾病的评估的诊断主要是有用的。

简介：梅花针叩刺头部，背部和腹部，并根据辨证配穴治疗更年期综合征以失眠为主症的患者50例，并与西药；台疗50例相对照．悔花针组近期疗效和远期疗效均好于对照组(P<0．01)。

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简介：Preoperativestagingoftheaxillainwomenwithinvasivebreastcancerusingultrasound-guidedneedlebiopsy(UNB)identifiesapproximately50%ofpatientswithaxillarynodalmetastasespriortosurgicalintervention.Althoughmoderatelysensitive,itisahighlyspecificstagingstrategythatisrarelyfalsely-positive,henceapositiveUNBallowspatientstobetriagedtoaxillarylymph-nodedissection(ALND)avoidingpotentiallyunnecessarysentinelnodebiopsy(SNB).Inthisreview,weextendourpreviousworkthroughanupdatedliteraturesearch,focusingonstudiesthatreportdataonUNButility.Basedondatafor10,934breastcancerpatients,sourcedfrom35studies,apositiveUNBallowedtriageof1,745cases(simpleproportion16%)toaxillarysurgicaltreatment:theutilityofUNBwasamedian19.8%[interquartilerange(IQR)11.6%-26.7%]acrossthesestudies.Wealsomodelleddatafromasubgroupofstudies,andestimatedthatamongstpatientswithmetastasestoaxillarynodes,theoddsratio(OR)forhighnodaldiseaseburdenforapositiveUNBversusanegativeUNBwas4.38[95%confidenceinterval(95%CI):3.13,6.13],P<0.001.Fromthismodel,theestimatedproportionwithhighnodaldiseaseburdenwas58.9%(95%CI:50.2%,67.0%)forapositiveUNB,whereastheestimatedproportionwithhighnodaldiseaseburdenwas24.6%(95%CI:17.7%,33.2%)ifUNBwasnegative.Overall,axillaryUNBhasgoodclinicalutilityandapositiveUNBcaneffectivelytriagetoALND.However,theevolvinglandscapeofaxillarysurgicaltreatmentmeansthatUNBwillhaverelativelylessutilitywheresurgeonshavemodifiedtheirpracticetoomissionofALNDforminimalnodalmetastaticdisease.

简介：Differentsystemshavebeenusedovertheyearstodeliverdrugparticlestothehumanskinforpharmaceuticaleffect.Researchhasbeendonetoimprovetheperformanceandflexibilityofthesesystems.Inrecentyearsauniquesystemcalledthetransdermaldrugdeliveryhasbeendeveloped.Transdermaldrugdeliveryopenedanewdoorinthefieldofdrugdeliveryasitismoreflexibleandoffersbetterperformancethantheconventionalsystems.Theprincipleofthissystemistoacceleratedrugparticleswithahighspeedgasflow.Amongdifferenttransdermaldrugdeliverysystemswewillconcentrateonthecontourshocktubesysteminthispaper.Acontouredshocktubeisconsistsofarupturechamber,ashocktubeandasupersonicnozzlesection.Thedrugparticlesareretainedbetweenasetofburstingdiaphragm.Whenthediaphragmisrupturedatacertainpressure,ahighspeedunsteadyflowisinitiatedthroughtheshocktubewhichacceleratestheparticles.Computationalfluiddynamicsisusedtosimulateandanalyzetheflowfield.TheDPM(discretephasemethod)isusedtomodeltheparticleflow.AsanunsteadyflowisinitiatedthoughtheshocktubethedragcorrelationproposedbyIgraetalisusedotherthanthestandarddragcorrelation.Theparticlevelocitiesatdifferentsectionsincludingthenozzleexitareinvestigatedunderdifferentoperatingconditions.Staticpressurehistoriesindifferentsectionsintheshocktubeareinvestigatedtoanalyzetheflowfield.Theimportantaspectsofthegasandparticledynamicsintheshocktubearediscussedandanalyzedindetails.

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简介：Osteoarthritisofthekneejointisoneoftheosteoarthropathyandisoftenseeninmid-agedandoldpeopleinclinic.Uptonow,therehasbeennoanyeffectivemedicationtotreatit.Theauthoremployedacupuncturewiththeneedlewarmedbyburningmoxaandachievedsatisfactoryresults.Hereisthereport.

简介：Toimproveglobalcontrolofdiseaseandreduceglobaltoxicity,acomplexseeddistributionpatternshouldbeachievedwithgreataccuracyduringbrachytherapy.However,theinteractionbetweentheneedleandprostatewillcauselargedeformationofsofttissue.Asaresult,seedswillbemisplaced,sharpdemarcationbetweenirradiatedvolumeandhealthystructuresisunavailableandthiswillcausesideeffectssuchasimpotenceandurinaryincontinence.Inthispaper,a3Dnonlineardynamicfiniteelements...

简介：这篇文章的目的是作为安慰剂针估计临床的证据为或对非渗透的假冒的针的令人目眩的效果。这系统的评论包括了作为安慰剂针拿非渗透的假冒的针灸的针灸的使随机化的控制审判(RCT)。系统的搜索在13个电子数据库被进行直到2012年7月：Medline，PubMed，Cochrane图书馆，CINAHL，EMBASE，一个中国医药数据库。没有语言限制，所有平行或为非渗透的针的令人目眩的效果的针灸的转线路RCT被选择。最后，完全，7RCT满足了包括标准。在结论，我们的系统的评论和元分析证明非渗透的针是为在针灸RCT的安慰剂控制的一台有效仪器。

简介：Endoscopicultrasonography-guidedfine-needleaspiration（EUS-FNA）hasbeenappliedtopancreaticobiliarylesionssincethe1990sandisinwidespreadusethroughouttheworldtoday.Weusedthismethodtoconfirmthepathologicalevidenceofthepancreaticobiliarylesionsandtoperformsuitabletherapies.ComplicationsofEUS-FNAarequiterare,butsomeofthemaresevere.OperatorsshouldmasterconventionalEUSobservationandexperienceaminimumof20-30casesofsupervisedEUS-FNAonnon-pancreaticandpancreaticlesionsbeforeattemptingsoloEUSFNA.StudiesconductedonpancreaticobiliaryEUSFNAhavefocusedonselectionofsuitableinstruments（e.g.,needleselection）andsamplingtechniques（e.g.,fanningmethod,suctionlevel,withorwithoutastylet,optimumnumberofpasses）.Today,thediagnosticabilityofEUS-FNAisstillimproving;thedetectionofpancreaticcancer（PC）currentlyhasasensitivityof90%-95%andspecificityof95%-100%.InadditiontoPC,avarietyofrarepancreatictumorscanbediscriminatedbyconductingimmunohistochemistryontheFNAmaterials.Aflexible,largecaliberneedlehasbeenusedtoobtainalargepieceoftissue,whichcanprovidesufficienthistologicalinformationtobehelpfulinclassifyingbenignpancreaticlesions.EUSFNAcansupplyhighdiagnosticyieldsevenforbiliarylesionsorperi-pancreaticobiliarylymphnodes.ThisreviewfocusesontheclinicalaspectsofEUS-FNAinthepancreaticobiliaryfield,withtheaimofprovidinginformationthatcanenablemoreaccurateandefficientdiagnosis.

简介：Objective:Toobservethetherapeuticeffectofcomprehensiveplum-blossommagneticneedletherapyonprolapseoflumbarintervertebraldisc.Methods:247casesofprolapseoflumbarintervertebraldiscweretreatedfirstwithmanualtreatmentandthenwithplum-blossommagneticneedletherapyandeffect-increasingpadtherapyatspecifiedpointsandreactivepoints.Results:Aftertreatmentfor2therapeuticcourses,153caseswerecuredaccountingfor61.94%,71casesweremarkedlyeffectiveaccountingfor28.75%,22caseswereimprovedaccountingfor8.91%andtherestonefailed,accountingfor0.45%.Conclusion:Thecomprehensiveplum-blossommagneticneedletherapyhasabettertherapeuticeffectonprolapseoflumbarintervertebraldisc.

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简介：Transperineal前列腺活体检视是能被用来从前列腺获得组织学的样品的一个过程。两个都改进活体检视核心样品和前列腺癌症察觉的质量，我们当前正在执行比较用18G针获得到用16G针获得的那些的前列腺活体检视样品的未来的、使随机化的试用。这初步的研究的目的是在两个组评估疼痛和复杂并发症率以便估计与一根更大的口径针执行前列腺活体检视是否是一个可行过程。经历transperineal前列腺活体检视的187个病人有希望地被评估并且把组划分了成二。第一个组(94个病人，组织A)用16G针和第二个组收到了transperineal前列腺活体检视(93个病人，组织B)与18G针经历了transperineal前列腺活体检视。麻醉在所有题目在prostatic顶与单个会阴的注射被获得。视觉类似物规模(管)和面部表情规模(FES)被用来在每个组在过程的多重步期间估计疼痛。因为它能潜在地影响病人们经历了的疼痛和复杂并发症，一张详细问询表被用来关于药使用获得信息。在过程以后的二个星期，早、迟了的复杂并发症被评估。统计分析用非参量的测试被执行。前列腺特定的抗原(PSA)和药使用在在二个组之间的基线是类似的。疼痛没在18-和16个G针组之间显著地在前列腺活体检视，与VAS和FES仪器一起被测量，期间不同，并且没有重要差别处于在这些组之间的早或迟了的复杂并发症率被发现。有16G针的Transperineal前列腺活体检视以疼痛和复杂并发症率是一个可行过程。有更大的耐心的人口的进一步的研究被要求估计这个过程是否能改进前列腺癌症察觉率。

简介：AbstractBackground:Contrast-enhanced ultrasound (CEUS) can detect lesions hidden in inflammatory regions and find necrosis or areas of severe fibrosis within the lesion. This retrospective study aimed to compare the diagnostic accuracy of solid pancreatic lesions using percutaneous ultrasound (US)-guided fine-needle aspiration (FNA) with or without CEUS assessment.Methods:Clinical, imaging, and pathologic data of 181 patients from January 2014 to December 2018 in Pecking Union Medical College Hospital, with solid pancreatic masses who underwent percutaneous US-FNA and ThinPrep cytologic test were retrospectively evaluated. Patients were divided into CEUS and US groups according to whether CEUS was performed before the biopsy. According to FNA cytology diagnoses, we combined non-diagnostic, neoplastic, and negative cases into a negative category. The positive category included malignant, suspicious, and atypical cases. The final diagnosis was confirmed by pathology or clinical and radiological follow-up for at least 12 months. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of US-FNA were evaluated between the two groups.Results:This study enrolled 107 male and 74 female patients (average age: 60 years). There were 58 cases in the US group and 123 cases in the CEUS group. No statistically significant differences in age, gender, or lesion size were found between the two groups. The diagnostic accuracy of the CEUS group was 95.1% (117/123), which was higher than the 86.2% (50/58) observed in the US group (P = 0.036). The sensitivity, specificity, PPV, and NPV of the CEUS group were increased by 7.5%, 16.7%, 3.4%, and 18.8%, respectively, compared with the US group. However, the differences of the two groups were not statistically significant.Conclusions:Compared with the conventional US, the use of CEUS could improve the biopsy accuracy and avoid the need for a repeat biopsy, especially for some complicated FNA cases.

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简介：hydroxyapatite(哈)涂层在对待H2O2的碳/碳(C/C)上被完成通过热水地对待和在超声的水下面在一个氨答案加热扔的CaHPO4涂层的正式就职合成洗澡。然后，这哈涂层被放在一个NH4F答案并且热水地再对待制作氟化的hydroxyapatite(联邦住房管理局)为在353，373，393和413K的24h的涂层分别地。结构，形态学和HA和联邦住房管理局涂层的化学作文被SEM，XRD，版本和FTIR描绘，并且粘着性和这些联邦住房管理局涂层的化学稳定性被擦伤测试和沉浸测试分别地检验。结果证明同样准备的联邦住房管理局涂层包含了像针或像条纹的晶体，与那些不同HA涂层。作为加氟作用温度玫瑰，FHA涂层的粘着性首先在在353和393K之间的温度从34.8～40.9N增加了，然后在413K减少了到24.2N，当FHA涂层的溶解率稳定地减少了时。为FHA涂层的性质变化的原因被分析涂层的形态学，作文和结构建议。