简介:重点词汇1.allowv.允许;准许Myparentsdon’tallowmetostayuplate.我父母不允许我熬夜。拓展(1)allowsbtodosth允许某人做某事(2)beallowedtodosth被允许做某事MrSmithallowsMiketodrivethere.史密斯先生允许迈克开车去那里。Heshouldbeallowedtohaveabreak.应该允许他休息一下。2.dealn.协议;交易Listen.Thisisthedeal.听着,下面是我们达成的协议。It’sadeal!就这么办吧!
简介:Inthispaper,weproposealocalfuzzymethodbasedontheideaof"p-strong"communitytodetectthedisjointandoverlappingcommunitiesinnetworks.Inthemethod,arefinedagglomerationruleisdesignedforagglomeratingnodesintolocalcommunities,andtheoverlappingnodesaredetectedbasedontheideaofmakingeachcommunitystrong.Weproposeacontributioncoefficientbvcitomeasurethecontributionofanoverlappingnodetoeachofitsbelongingcommunities,andthefuzzycoefficientsoftheoverlappingnodecanbeobtainedbynormalizingthebvcitoallitsbelongingcommunities.Therunningtimeofourmethodisanalyzedandvarieslinearlywithnetworksize.Weinvestigateourmethodonthecomputergeneratednetworksandrealnetworks.Thetestingresultsindicatethattheaccuracyofourmethodindetectingdisjointcommunitiesishigherthanthoseoftheexistinglocalmethodsandourmethodisefficientfordetectingtheoverlappingnodeswithfuzzycoefficients.Furthermore,thelocaloptimizingschemeusedinourmethodallowsustopartlysolvetheresolutionproblemoftheglobalmodularity.
简介:Themagnetoresistanceeffectofap–njunctionunderanelectricfieldwhichisintroducedbythegatevoltageatroomtemperatureisinvestigatedbysimulation.Asauxiliarymodels,theLombardiCVTmodelandcarriergenerationrecombinationmodelareintroducedintoadrift-diffusiontransportmodelandcarriercontinuityequations.Alltheequationsarediscretizedbythefinite-differencemethodandtheboxintegrationmethodandthensolvedbyNewtoniteration.Takingadvantageofthosemodelsandmethods,anabruptjunctionwithuniformdopingisstudiedsystematically,andthemagnetoresistanceasafunctionofdopingconcentration,SiO_2thicknessandgeometricalsizeisalsoinvestigated.Thesimulationresultsshowthatthemagnetoresistance(MR)canbecontrolledsubstantiallybythegateandisdependentonthepolarityofthemagneticfield.
简介:目的:探讨结直肠癌组织中正谷胱甘肽-S-转移酶-π(GST-π)、DNA拓扑异构酶(TopoⅡ)、P-糖蛋白(P-gp)、Ki-67抗原(Ki-67)及P53基因(P53)的表达及临床意义。方法:选取2014年1月-2015年6月本院收治的术前未做化疗的24例结直肠癌患者作为研究对象,根据预后情况将其分为预后生存〈1年组8例和预后生存〉1年组16例,分析GST-π、TopoⅡ、P-gp、Ki-67及P53表达与临床病理特征的关系,比较两组患者GST-π、TopoⅡ、P-gp、Ki-67及P53的表达阳性率。结果:24例结直肠癌患者,GST-π表达阳性9例(低度表达7例,中度表达2例),TopoⅡ表达阳性23例(低度表达15例,中度表达8例),P-gp表达阳性23例(低度表达8例,中度表达15例),Ki-67表达阳性24例(低度表达3例,中度表达11例,高度表达10例),P53表达阳性10例(低度表达3例,中度表达3例,高度表达4例)。预后生存〉1年组GST-π、P53的表达阳性率均为12.5%,显著低于预后生存〈1年组,比较差异均有统计学意义(P〈0.05),而在TopoⅡ、P-gp、Ki-67方面比较差异无统计学意义(P〉0.05)。结论:联合检测GST-π、TopoⅡ、P-gp、Ki-67及P53的表达有助于结直肠癌早期发现及评估患者预后,值得临床推广。
简介:摘要肺癌的发生、扩增、浸润、扩散及转移与机体免疫息息相关。机体对肿瘤的免疫以细胞免疫为主,其中T淋巴细胞(以下简称T细胞)直接或间接参与肿瘤发展的各个阶段,包括机体对肿瘤细胞的免疫监视、肿瘤细胞的免疫逃逸作用。本文就T淋巴细胞亚群在肺癌各型病理类型中的研究及临床治疗研究作一综述。