简介：　　【摘 要】 目的：探究新活素联合左西孟旦治疗慢性心衰急性发作的临床效果。方法：将2018年3月至2019年3月于我科接受治疗的40例慢性心衰患者作为研究对象，随机分为观察组和对照组，每组20例。对照组单用新活素治疗，观察组应用新活素联合左西孟旦治疗，比较两组患者治疗前后的尿量以及BUN等情况。结果：治疗后，观察组和对照组患者的尿量均有所增加，观察组和对照组患者的BUN均有所降低，而观察组的改善情况均优于对照组，且观察组患者心功能明显改善，组间数据差异明显，具有统计学意义（P

简介：　　【摘要】目的：探究地高辛加倍他乐克用于治疗充血性心衰伴快速房颤的临床观察。方法：选择我院 2018年 3月至 2019年 3月收治的 78例充血性心衰伴快速房颤患者，采取随机分组的方法将患者分为对照组和实验组，每组 39例，所有患者在入院前均接受常规急救和护理，对照组患者将给予地高辛治疗，实验组患者将给予地高辛加倍他乐克治疗。然后对两组患者在治疗后的心率、左心室射血分数（ LVEF）和总有效率进行对比。结果：在临床经过对比后发现，对照组患者的心率为（ 89.3±11.4）次 /min，实验组患者的心率为（ 78.6±8.9）次 /min，实验组患者在治疗后心率改善明显高于对照组，差异具有统计学意义（ P<0.05） ;对照组患者的 LVEF（ 43.1±2.3） %，实验组患者的 LVEF（ 52.2±2.3） %，实验组患者的 LVEF相对于对照组更加接近正常水平，差异具有统计学意义（ P<0.05） ;实验组患者的治疗总有效率为 97.43%（ 38），对照组患者的治疗总有效率为 79.48%（ 31），实验组患者的治疗总有效率明显高于对照组，差异具有统计学意义（ P<0.05）。结论：对患者使用地高辛加倍他乐克临床效果更为显著，能有效降低患者心理和改善 LVEF水平，且不会增加患者不良反应，用药安全性高，值得在临床中推广。  　　【关键词】充血性心衰 ;快速房颤 ;倍他乐克 ;地高辛  　 Objective: To explore the clinical observation of digoxin and metoprolol in the treatment of congestive heart failure with rapid atrial fibrillation. Methods: 78 patients with congestive heart failure with rapid atrial fibrillation in our hospital from March 2018 to March 2019 were selected and randomly divided into control group and experimental group, 39 cases in each group. All patients received routine first aid and nursing before admission. Patients in the control group were given digoxin treatment, while patients in the experimental group were given digoxin treatment. Then the heart rate, left ventricular ejection fraction (LVEF) and total effective rate of the two groups were compared. Results: after clinical comparison, it was found that the heart rate of patients in the control group was (89.3 ± 11.4) beats / min, and the heart rate of patients in the experimental group was (78.6 ± 8.9) beats / min. the improvement of heart rate in the experimental group was significantly higher than that in the control group (P < 0.05); The LVEF of the control group was (43.1 ± 2.3)%, and that of the experimental group was (52.2 ± 2.3)%. The LVEF of the experimental group was closer to the normal level compared with the control group (P < 0.05); The total effective rate of the experimental group was 97.43% (38), and that of the control group was 79.48% (31). The total effective rate of the experimental group was significantly higher than that of the control group (P < 0.05). Conclusion: the clinical effect of digoxin double taloc is more significant, which can effectively reduce the psychological status of patients and improve the level of LVEF, and will not increase the adverse reactions of patients, so it is worthy of clinical promotion.

简介：【摘要】目的 探讨双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效。方法 选取 2019年 3月 ~2020年 4月在我院进行治疗的幽门螺杆菌超标的儿童 100例进行观察研究，根据随机分配的原则将 100例患者分为观察组和对照组，每组各 50例。对照组患者采用奥美拉唑对患者进行治疗，观察组患者则采用双歧杆菌四联活菌片联合三联疗法对幽门螺杆菌感染的儿童进行治疗。通过对比两组患者的并发症发生率及治疗效果进行评判，判断双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效。结果 观察组患者的并发症发生率低于对照组患者，观察组患者的治疗效果高于对照组患者，差异显著（ p ），有统计学意义。结论 通过对比两组患者的研究结果，证明双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效良好，能够有效的减少患者的不良反应发生率，降低患者及患者家属的心理压力，提升医院的治疗效率，是患者及患者家属放心的优质护理方案，具有很高的临床学价值，值得临床推广用。

简介：

简介：　　 [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月～ 2020年 1月我院收治的溃疡性结肠炎患者 80例，随机分为两组，每组各 40例，两组患者均予常规对症治疗，同时两组均予美沙拉嗪缓释颗粒，观察组同时加用双歧三联活菌胶囊，治疗后比较两组患者治疗后的临床疗效，以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%，显著高于对照组的总有效率 70.00%，两组疗效比较差异具有显著性（ P<0.05）。治疗后，两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低（ P<0.05）。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组（ P<0.05）。观察组患者治疗后的临床症状积分为（ 2.56±0.85）分，与治疗前及对照组比较，差异有统计学意义（ P<0.05）。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切，且可以抑制炎症反应，值得临床推广和应用。  　　 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子  　 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.