简介：目的：使用Pentacam三维眼前段分析仪比较高度近视眼与正常人（正视眼）中央前房深度（centralanteriorchamberdepth,CACD）和前房角（anteriorchamberangle,ACA）两项前房参数差异,进一步了解高度近视眼的解剖学特点。方法：收集2010-10/2011-06在我院门诊就诊的正视眼82例,收集同期我院门诊与准分子激光中心就诊的高度近视眼68例,采用Pentacam三维眼前段分析仪测量CACD和ACA。对高度近视组与正视眼组的前房参数值进行两样本t检验,比较两组间参数有无差异。结果：Pentacam三维眼前段分析仪测得正常人CACD平均值为3.02±0.47mm,ACA平均值为33.26°±6.20°。高度近视眼的CACD平均值为3.24±0.38mm,ACA的平均值为39.55°±6.68°。高度近视眼与正视眼的两项前房参数值均存在显著性差异（均P〈0.05）。结论：Pentacam三维眼前段分析仪测量前房参数,高度近视眼与正视眼相比中央前房深度深、前房角宽。

简介：目的：分析眼部黑色素瘤临床和病理学特点,以利于早期正确诊断和治疗。方法：回顾性系列病例研究。收集我院2001-08/2011-08门诊及住院眼部黑色素瘤24例,复习患者的临床和病理资料,所有病例采用常规石蜡切片、HE染色,部分病例常规诊断困难的加做S-100蛋白和HMB-45免疫组织化学染色。Excel建立数据库,应用SPSS17.0软件进行统计学分析。结果：患者24例均为单眼发病,男13例,女11例;左眼14例,右眼10例;3例眼睑恶性黑色素瘤,6例原发性结膜黑色素瘤;15例葡萄膜黑色素瘤。结论：黑色素瘤组织病理学变化多样,多数病例常规病理确诊,免疫组织化学对黑色素瘤诊断和鉴别诊断有重要价值。

简介：AIM:Toinvestigatetheaccuracyofintraocularpressure(IOP)asmeasuredbyaReichertOcularResponseAnalyzer(ORA),aswellastherelationshipbetweencentralcornealthickness(CCT)andIOPasmeasuredbyORA,Goldmannapplanationtonometry(GAT),anddynamiccontourtonometry(DCT).·METHODS:Atotalof158healthyindividuals(296eyes)werechosenrandomlyformeasurementofIOP.AfterCCTwasmeasuredusingA-ultrasound(A-US),IOPwasmeasuredbyORA,GAT,andDCTdevicesinarandomizedorder.TheIOPvaluesacquiredusingeachofthethreetonometrieswerecompared,andtherelationshipbetweenCCTandIOPvalueswereanalyzedseparately.TwoIOPvalues,Goldmann-correlatedIOPvalue(IOPg)andcorneal-compensatedintraocularpressure(IOPcc),weregotusingORA.ThreegroupsweredefinedaccordingtoCCT:1)thincornea(CCT<520μm);2)normal-thicknesscornea(CCT:520-580μm);and3)thickcornea(CCT>580μm)groups.·RESULTS:Innormalsubjects,IOPmeasurementswere14.95±2.99mmHgwithORA(IOPg),15.21±2.77mmHgwithORA(IOPcc),15.22±2.77mmHgwithGAT,and15.49±2.56mmHgwithDCT.Meandifferenceswere0.01±2.29mmHgbetweenIOPccandGAT(P>0.05)and0.28±2.20mmHgbetweenIOPccandDC(P>0.05).TherewasagreatercorrelationbetweenIOPccandDCT(r=0.946,P=0.000)thanthatbetweenIOPccandGAT(r=0.845,P=0.000).DCThadasignificantcorrelationwithGAT(r=0.854,P=0.000).GATwasmoderatelycorrelatedwithCCT(r=0.296,P<0.001),whileIOPccshowedaweakbutsignificantcorrelationwithCCT(r=0.155,P=0.007).TherewasastrongnegativecorrelationbetweenCCTandthedifferencebetweenIOPccandGAT(r=-0.803,P=0.000),withevery10increaseinCCTresultinginanincreaseinthisdifferenceof0.35mmHg.Thethickcorneagroup(CCT>580μm)showedtheleastsignificantcorrelationbetweenIOPccandGAT(r=0.859,P=0.000);whilethethincorneagroup(CCT<520μm)hadthemostsignificantcorrelationbetweenIOPccandGAT(r=0.926,P=0.000).ThecorrelateddifferencesbetweenIOPccan

简介：目的探讨在规模化复明工程中应用小切口非超声乳化白内障手术的环节控制。方法对1888例（1888眼）施行小切口白内障囊外摘除联合人工晶体植入术,分析手术流程及效果。结果术后第一天时,裸眼视力〉=0.5者1056例;占55.93%;〉=0.3者396例,占20.97%;〈0.3者395例,占20.92%;〈0.05者41例,占2.17%。结论在基层条件下充分准备,优化技术管理,在简单的条件下充分利用有限卫生资源,可让更多的白内障患者脱盲。

简介：<正>DearSir,IamDr.YunLi,fromtheSecondHospitalAffiliatedtoNanchangUniversity,JiangxiProvince,China.IwritetopresentacasereportofIOLimplantationin

简介：AIM:Toinvestigatetheefficacyofnon-buckledvitrectomywithclassicalendotamponadeagentsinthetreatmentofprimaryretinaldetachment(RD)complicatedbyinferiorbreaksandproliferativevitreoretinophathy(PVR).METHODS:Aretrospective,consecutiveandcaseseriesstudyof40patientswithinferiorbreakRDandPVR≥C1wasconducted.Allpatientsunderwentastandard3-port20-gaugeparsplanavitrectomy(PPV)withgasorsiliconeoiltamponadewithoutsupplementaryscleralbuckling.Thevitreousandallproliferativemembranewerecompletelyremoved,andretinectomywasperformedwhennecessary.Themeanfollow-upwas12.5months.Theprimaryandfinalanatomicsuccessrate,visualacuityandcomplicationswererecordedandanalyzed.RESULTS:Primaryanatomicsuccessratewasachievedin35of40eyes(87.5%)andthefinalanatomicsuccessratewas100%.ThemostcommoncauseofredetachmentwasrecurrentPVR.Thebest-correctedvisualacuity(BCVA)atfinalfollow-upwasimprovedin34eyes(85%),remainedstablein1eye(2.5%),andworsenedin5eyes(12.5%).Themeanvisualacuityatfinalfollow-upwasimprovedsignificantly(P=0.000).CONCLUSION:ThisretrospectivestudyprovidesevidencethatvitrectomywithoutscleralbucklingseemedtobeaneffectivetreatmentforinferiorbreakRDwithPVR.Withcompleteremovalofvitreousandproliferativemembranesandtimingofretinectomy,theinferiorbreakswhichcomplicatedwithPVRcouldbeclosedsuccessfullywithoutadditionalscleralbuckling.

简介：目的：应用频域光学相干断层扫描（opticalcoherencetomography,OCT）对特发性和继发性黄斑前膜（macularepiretinalmembrane,ERM）的形态特征、黄斑中心凹厚度及其与视力的关系进行对比研究。方法：应用频域OCT观察用裂隙灯显微镜、荧光素眼底血管造影（fundusfluoresceinangiography,FFA）及OCT确诊为特发性ERM（92例112眼）、继发性ERM（78例96眼）的患者,观察前膜的形态特征、定量测量前膜及其下视网膜厚度、分析黄斑中心凹厚度与视力的关系。结果：ERM的OCT图像表现为视网膜神经上皮层表面厚薄不一的高反射光带,主要表现为前膜与视网膜内表面出现局灶及大部分粘连,其次表现为黄斑中心凹变浅或消失、神经上皮层增厚、黄斑水肿。特发性ERM患者视网膜平均厚度为398.32±112.07μm,前膜的平均厚度为52.28±9.65μm;继发性ERM患者视网膜平均厚度为416.87±104.17μm,前膜的平均厚度为57.05±10.33μm。两组间的差异无统计学意义（P〉0.05）。在相同视力区间,两组黄斑中心凹厚度比较,差异无统计学意义（P〉0.05）。而分别在两组及同组不同视力区间之间,黄斑中心凹厚度差异有统计学意义（P〈0.05）。结论：OCT可以客观地显示ERM及黄斑部组织结构的改变,并能定量检测ERM、中心凹视网膜厚度变化,是ERM可靠的检测手段。

简介：AIM:Tostudythedistributionofocularhigher-orderaberrations(HOAs)andmesopicpupilsizeinindividualsscreenedforrefractivesurgery.·METHODS:OcularHOAsandmesopicpupilsizewerestudiedin2458eyesof1240patientswithmyopia,myopicastigmatismandcompoundmyopicastigmatismand215eyesof110patientswithhyperopia,hyperopicastigmatismandcompoundhyperopicastigmatismusingtheZywaveaberrometer(Busch&Lomb).Allpatientshadcorrectablerefractiveerrorswithoutahistoryofrefractivesurgeryorunderlyingdiseases.Root-mean-squarevaluesofHOAs,totalsphericalaberration,totalcomaandmesopicpupilsizewereanalyzed.OcularHOAsweremeasuredacrossa≥6.0mmpupil,andpupilsizemeasurementswereperformedunderthemesopiccondition.·RESULTS:ThemeanvaluesofHOAs,totalsphericalaberrationandtotalcomainthemyopicgroupwere0.369μm,±0.233,0.133±0.112μmand0.330±0.188μm,respectively.InthehyperopicgroupthemeanvaluesofHOAs,totalsphericalaberrationandtotalcomawere0.418μm±0.214,0.202±0.209μmand0.343±0.201μm,respectively.HyperopesshowedgreatertotalHOAs(P<0.01)andtotalsphericalaberration(P<0.01)comparedtomyopes.Inage-matchedanalysis,onlytheamountoftotalsphericalaberrationwashigherinthehyperopicgroup(P=0.05).Mesopicpupilsizeinthemyopicgroupwaslarger(P≤0.05).·CONCLUSION:TheresultssuggestedthatsignificantlevelsofHOAswerefoundinbothgroupswhichareimportantforplanningrefractivesurgeriesonIranians.Thereweresignificantlyhigherlevelsoftotalsphericalaberrationinhyperopescomparedtomyopes.Mesopicpupilsizewaslargerinmyopicgroup.

简介：AIM:Toexaminetheα-Galgeneexpressionanddistributioninthedifferentspecies/genusanddevelopingphaseanimalocularsurfacetissue.METHODS:α-Galbindingassaywerecarriedoutonvariousanimaleyesections.Photograph,slit-lampobservationonvariouseyeshowednormalcornealtransparence.RESULTS:Astrongα-Galexpressionininvertebratesandsomevertebratesoculartissue,butnoα-Galbindinginbirds,fishandmammal.α-Galexpressionchangeinthedevelopmentofmiceocularsurfacetissue(exceptsclera)anddisplaygenusdependencyinthedifferentmurineocularsurfacetissue.CONCLUSION:Thisstudyidentifiedspecificα-Galepitopesbindingareaintheocularsurfaceofseveralspeciesandmaysolvetheproblemthatnaiveocularsurfacemaybeusedasnaturalα-Galgeneknockoutmodel/highriskimmunologicrejectionmodelorocularsurfacescaffoldmaterial.

简介：AIM:ToevaluatethecornealendothelialcelldensityandmorphologyinChinesepatientswithpseudoexfoliationsyndrome(PEX).·METHODS:Medicalrecordsof16patients(20eyes)withPEXwhopresentedtoourinstitutionbetweenJuly2008andJune2010wereretrospectivelyreviewed.Thirteeneyeshadcombinedglaucoma.Theinformationoffiveapparentlynormalfelloweyesinthesepatientswasalsorecorded.Lefteyesof20patientswithbilateralsenilecataractsbutnoothereyediseasewereincludedascontrols.Specularmicroscopywasperformedinalleyestoanalyzeforcornealendothelialcelldensityandmorphology.Celldensity,coefficientofvariationincellsize,andpercentageofhexagonalcellsincornealendotheliumwereevaluated.·RESULTS:ThemeancornealendothelialcelldensityinthePEXeyeswas2298±239cells/mm2,significantlylowerthanthatinthecataracteyes(2652±18cells/mm2,P=0.026),buttherewerenosignificantdifferencesincoefficientofvariationofcellsizeandfrequencyofhexagonalitybetweenthesetwogroups.NosignificantdifferencesinthethreeparameterswerefoundbetweentheapparentlynormalfelloweyesandthePEXeyesorthecataracteyes,orbetweenthePEXeyeswithandwithoutglaucoma.·CONCLUSION:CornealendothelialcelldensitymaydecreaseinChinesepatientswithPEX.ThedevelopmentofglaucomainPEXeyesdoesnotseemtoberelatedwiththechangeincornealendothelialcelldensityormorphology.

简介：手法小切口白内障术（manualsmallincisioncataractsurgepy，MSICS）特别是在发展中国家已广泛应用于临床手术。本文旨在比较传统白内障囊外摘除术（extracapsularcataractextraction，ECCE）、MSICS以及超声乳化白内障吸除术治疗效果以及安全性（术中并发症以及术后并发症）。通过使用PubMed搜索引擎，我们收集了传统ECCE、MSICS以及超声乳化白内障吸除术的相关文献，以评价其安全性和治疗效果。同时，也参考了国内出版的相关文献。结果发现，与超声乳化白内障吸除术相比，传统ECCE以及MSICS也取得了很好的治疗效果，并且具有并发症少等优点。MSICS不需要依赖昂贵的仪器，并且具有手术快速、费用低廉以及技术门槛低等特点，特别适用于硬核白内障的治疗。虽然在白内障手术治疗过程中MSICS需要一定的技术和耐心，但它仍然是一种安全、有效、经济治疗手段，特别是在发展中国家可以替代超声乳化进行白内障的治疗。

简介：AIM:Toexaminetheexpressionofsurvivinandvascularendothelialgrowthfactor(VEGF)duringthedevelopmentofretinalneovascularization(NV)inamousemodel.·METHODS:Awell-characterizedmurinemodelofretinalNVwasusedtostudytheexpressionofsurvivinandVEGF.NVoftheretinawasinducedinmicebyexposureto75%O2frompostnataldayP7toP12,followedbyreturntoroomairfromP12toP17.ExpressionofsurvivinandVEGFproteinwasanalyzedbyImmunohistochemistry.Inaddition,mousemodelofproliferativeretinopathywasanalyzedbyretinalfluoresceinangiographyandquantificationanalysis.·RESULTS:Thenormalmicehadbothsuperfiekalanddeepvascularlayersthatextendedfromtheopticnervetotheperiphery.Inintraocularpressure(IOP)micewerecharacterizedbyrepresentatypicalpatternofpathologicalretinalNV.Therearelessorlittlenucleiofnewvesselsvascularendothelialcellbreakingthroughtheinnerretinalthaninretinopathyofprematurity(ROP)mice,largeclustersofbloodvesselswereadherenttotheinternallimitingmembrane(ILM)(0.27±0.20vs23.38±1.027,t=9.454,P<0.001).DuringtheangiogenicperiodfromP13toP17,survivinandVEGFproteinexpressionincreasedinexperimentalretinascomparedwithcontrolsamples(2.56±0.46vs3.34±0.40,t=17.43,P<0.01:2.18±0.75vs4.34±0.25,t=19.61,P<0.01).ProteinlevelsofVEGFandsurvivnhassignificantlypositivecorrelation(P<0.05,r=0.411).·CONCLUSION:CorrelationwasmadeattheproteinlevelsofsurvivinexpressioncomparedwiththatofVEGFinamurinemodelofretinalNV,whichsuggestsatemporalroleforsurvivinandVEGFinnewvesselformationinresponsetohypoxicstimulation.

简介：<正>DearSir,IamProf.BeuyJoobfromSanitation1MedicalAcademicCenter,Bangkok,Thailand.Iwritetodiscusstherecentpublicationonproteomicanalysisindiabeticretinopathy(DR).Liuetal[1]concludedthattheirapproachbytwodimensionalfluorescencedifferencegelelectrophoresis(2D-DIGE)combinedwithmatrix-assistedlaser

简介：AIM:Toinvestigatethespecialtyoftranscranialsurgerythroughpterionalapproachforremovalofcranio-orbitaltumors,introducetheophthalmologicalexperiencesofenteringtheorbittoreducetheincidencerateofassociatedcomplicationsofthisoperation.·METHODS:Weperformedaretrospectiveanalysisofaseriesof37casesinvolvingpatientswhounderwenttranscranialsurgerythroughpterionalapproachfortreatmentofcranio-orbitaltumorsinourdepartmentinthepast8years.Pterionapproachcraniotomywasperformedtoallpatients.Afterremovingtumorsintheskullbytheneurosurgeon,ophthalmologistremovedtumorsinorbit.Wetookmeasuresbelowtodecreasecomplications,includinggroundingopticcanalthroughanabrasivedrillingwhennecessary,hangingvariousextraocularmusclestobeexposedforprotection,refrigeratingbyrefrigerationheadstoremovetumors,atlastsewinguporbitseptumaftersurgery.·RESULTS:Tumorswereremovedcompletelyin32cases,andincompletein5casesduetoextensiveinvasionintothecavernoussinusorsphenoidsinus.Ofallthecases,benigntumorsweredemonstratedin28cases(75.6%,28/37)andmalignantin9(24.3%,9/37).Themostcommonlesiontypewasmeningiomain11cases(29.7%,11/37).Extraocularmuscles(EOM)impairment,occurringin21cases(56.7%,21/37),wasthemostfrequentpostoperativecomplication.Themostseriousconsequencewasvisionlossoccurredin4cases(10.8%,4/37).Othercomplications,suchas11casesoftransientblepharoptosis29.7%(11/37),5casesofmydriasisin13.5%(5/7);2casesofcerebrospinalrhinorrheain5.4%(2/37).·CONCLUSION:Cranio-orbitaltumorscanberemovedcompletelyusingtranscranialapproach,andthepterionalapproachoffersexcellentexposure.Cooperationofinterdisciplinaryteamofneurosurgeonsandophthalmologistsconducestofulluseofrespectiveprofessionaladvantages.Theexperienceofophthalmicoperationtechnologycandecreaseoccurrenceofocularcomplicationsaftersurger

简介：AIM:Toinvestigatethelevelsofserumsolubleintercellularadhesionmolecules-1(sICAM-1)andneutrophilicexpressionofCD18inpatientswithvariousstagesofdiabeticretinopathyandtodeterminetheirdifferentexpressionpatterninthedevelopmentofdiabeticretinopathy(DR).·METHODS:LevelsofserumsICAM-1andCD18onthesurfaceofneutrophileweremeasuredin41DRpatients,theywereclassifiedinthreesubgroupsaccordingtothestageofretinopathyasdeterminedbyfund’sophthalmoscopy;10controlsubjectswerealsostudied.sICAM-1weremeasuredbyenzyme-linkedimmunosorbentassayandCD18byflowcytometry.·RESULTS:TheneutrophilicCD18expressionandserumsICAM-1levelwereallsignificantlyelevatedinalldiabeticsubgroupscomparedtocontrolsubjects(P<0.01).ThedifferencesofCD18andsICAM-1amongthediabeticsubgroupsweresignificantinCD18butnotinsICAM-1.TheprogressionofretinopathywasassociatedwithanincreasebothinCD18andinsICAM-1levelsbysimplecorrelationanalysis(β=0.74,P<0.001;β=0.38,P<0.01,respectively).ButstepwisemultipleregressionanalysisrevealedthatonlyCD18wasindependentdeterminantofretinopathy(β=1.04,P<0.01).·CONCLUSION:OurresultsconfirmthecontributionofendothelialandneutrophilicactivationinthedevelopmentofDRasindicatedbyincreasedlevelsofCD18andsICAM-1.However,adirectimplicationofCD18andICAM-1intheprogressionofDRcanbesupportedonlyintheCD18butnotICAM-1.CD18andICAM-1mayplaydifferentroleinthedevelopmentofdiabeticretinopathy.

简介：目的探讨耳源性颅内并发症的临床特点及诊治措施。方法回顾分析2003-2010年我科收治的21例耳源性颅内并发症患者的临床资料，病例包括脑脓肿9例、脑膜炎5例、静脉窦血栓性静脉炎4例、硬膜外脓肿3例，继发于胆脂瘤型中耳炎14例、骨疡型中耳炎3例、隐蔽性中耳炎2例、Modini畸形2例。21例均行耳部及头颅cT平扫检查，其中6例未发现颅内病变，经行磁共振成像（MRI）检查后确诊。分别行单纯乳突根治术8例、乳突根治术＋脑脓肿穿刺引流6例、乳突根治术＋颅钻孔脑脓肿引流1例、乳突根治术＋脑脓肿切除术1例、乳突根治术＋静脉窦切开脓肿清除及血栓取出2例、外淋巴漏修补术2例。结果随访1-2年，1例死亡，其余20例治愈，其中19例干耳，1例术腔仍有少量分泌物。全部患者颅内并发症无复发。结论胆脂瘤型和骨疡型中耳炎仍是耳源性颅内并发症的最常见病因，应提倡对这两种危险性中耳炎早期进行手术治疗。临床高度怀疑颅内并发症，CT平扫阴性病例，需行MRI检查。乳突切除进路的显微微创手术有效，无需开颅。

简介：目的探讨在持续性高眼压状态下行改进的小梁切除术的安全性及临床治疗效果。方法对49例（51眼）持续性高眼压状态的急性闭角型青光眼行如下改进的小梁切除术：1．术中先行前房穿刺并多次放液降压，2．隧道刀制作薄层大巩膜瓣并紧密缝合，3．术中散瞳、术毕皮质类固醇结膜下注射等。回顾性分析手术前后眼压控制情况、视力变化及手术并发症。结果术后观察随访1-6个月，眼压控制≤21mmHg者4611~：，术后视力较术前提高者42眼。本组病例均未出现脉络膜下爆发性出血、脉络膜脱离、恶性青光眼等严重术中、术后并发症。结论对持续高眼压状态的青光眼应积极手术治疗，改进后的小粱切除术可以取得满意疗效，并有效预防和减少并发症的发生。

简介：AIM:Toevaluatechangesintheanteriorchamberdepth(ACD),crystallinelensthickness(LT)anditsrefractivepowerafterlaserinsitukeratomileusis(LASIK).·METHODS:Inallcases,thepreoperativeandpostoperativecentralACDwhichweremeasuredwithPentacam,Orbscan,IOL-MasterandA-scanultrasonography,centralcornealtruenetpowerwhichwasmeasuredwiththePentacam,OrbscanandIOL-Master,axiallength(AL)whichwasmeasuredwithIOL-MasterandLTwhichwasmeasuredwiththeA-scanultrasonographywerecomparedusingthepairedsamplettest.OcularrefractiveerrorsandlensrefractivepoweratcornealplanewerecalculatedandtheircorrelationswerealsoevaluatedbeforeandafterLASIK.RESULTS:At1weekafterLASIK,LTandcrystallinelensrefractivepoweratcornealplane(Dlens)whichwereassociatedwiththeIOL-MasterandPentacamincreasedsignificantly(P≤0.005),ACDdecreasedsignificantly(P≤0.001),butnosignificantincreasewasobservedintheDlenswhichwasassociatedwiththeOrbscan(P=0.261).SignificantcorrelationsbetweenthechangesintheocularrefractiveerrorsandDlenswhichwereassociatedwiththePentacamwereobservedat1weekand6monthsafterLASIK(P=0.028;P=0.001).CONCLUSION:LTincreasedsignificantlyafterLASIK,andthismightpartiallyleadtoACDdecrease,Dlensincreaseandasmallquantityofmyopicregression.

简介：目的评价表麻下小切口手法劈核白内障摘除术联合人工晶状体植入术在大批量白内障复明手术中应用的临床效果。方法对我院从2007年4月到2011年10月实施该手术的1985例进行回顾性分析，分析手术方式的适宜性，治疗效果及并发症状况。结果术后视力明显提高，0．3及其以上者1849眼，占93％，O．05及其以上者1963眼，占99％，且手术时问短，并发症少，麻醉效果好。结论该手术适合在基层医院开展大批量白内障手术。

简介：AIM:Todescribethecharacteristicsofmodulationtransferfunction(MTF)ofanteriorcornealsurface,andobtainthethenormalreferencerangeofMTFatdifferentspatialfrequenciesandopticalzonesoftheanteriorcornealsurfaceinmyopes.·METHODS:Fourhundredeyesfrom200patientswereexaminedunderSIRIUScornealtopographysystem.PhoenisanalysissoftwarewasappliedtosimulatetheMTFcurvesofanteriorcornealsurfaceatverticalandhorizontalmeridiansatthe3,4,5,6,7mmopticalzonesofcornea.TheMTFvaluesatspatialfrequenciesof5,10,15,20,25,30,35,40,45,50,55and60cycles/degree(c/d)wereselected.·RESULTS:TheMTFcurveofanteriorcornealsurfacedecreasedrapidlyfromlowtointermediatefrequency(0-15cpd)atvariousopticalzonesofcornea,thevaluedecreasedto0slowlyathigherfrequency(>15cpd).Withtheincreaseoftheopticalzonesofcornea,MTFcurvedecreasedgradually.3)Intherangeof3mm-6mmopticalzonesofthecornea,theMTFvaluesmeasuredathorizontalmeridianweregreaterthanthecorrespondingvaluesathorizontalmeridianofeachspatialfrequency,thedifferencewasstatisticallysignificant(P<0.05).At7mmopticalzonesofcornea,theMTFvaluesmeasuredathorizontalmeridianwerelessthanthecorrespondingvaluesatverticalmeridianat10-60spatialfrequencies(cpd),andthedifferencewasstatisticallysignificantin25,30,35,40,45,50cpd(P<0.05).·CONCLUSION:MTFcanbeusedtodescribetheimagingqualityofopticalsystemsatanteriorcornealsurfaceobjectivelyindetail.