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297 个结果
  • 简介:旋转货摊房间的结构和行为试验性地在一把斜流动扇子被澄清。扇子特定速度是1140(r/min,m3/min,m),并且在设计流动率的全部的压力上升系数是0.345。外部casing墙上的静态的压力和在转子入口和插头的全部的压力用一个高反应压力变换器被测量。测量数据被DPLA技术,和结构的使用处理,旋转货摊房间的行为被获得。作为结果,货摊房间程度为环绕并且在货摊房间内的spanwise方向和压力分布被澄清。货摊房间繁殖的细节也被显示出。关键词斜流动扇子-旋转货摊房间-不稳定的流动-DPLA技术CLC数字TH432.2

  • 标签: 对角流风扇 不稳定流 DPLA技术 流速
  • 作者: Chen Yuan-Jia Ojeaburu Jeremiah V. Vortmeyer Alexander Yu Shuang Jensen Robert T.
  • 学科: 医药卫生 >
  • 创建时间:2020-08-10
  • 出处:《胰腺病学杂志(英文)》 2020年第01期
  • 机构:Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China; Digestive Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA,Digestive Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA,Molecular Pathogenesis Unit, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA,Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • 简介:AbstractPurpose:The pathogenesis of gastrinomas is largely unknown, and there is a lack of reliable genetic determinants that are useful to distinguish malignant and benign forms of this tumor or predict the prognosis of patients with this disease. Loss of heterozygosity (LOH) on chromosome 3p is reported to occur in pancreatic neuroendocrine tumors (PNETs) as well as in non-PNETs and its presence is reported to correlate with tumor prognosis in non-endocrine tumors. However, little data are available from prospective studies on gastrinomas.Experimental design:We assessed occurrence of 3p LOH in 24 gastrinomas and correlated its presence with tumor biological behavior and other clinicopathological features of gastrinomas.Results:Either 3p LOH or microsatellite instability involving 3p occurred in 11 of 24 tumors (46%). Seven (29%) gastrinomas had 3p LOH. Of the 7 gastrinomas with 3p LOH, 5 (71%) had 3p12 LOH with the marker D3S2406, which was the shortest region of highest overlap (SRO). Chromosome 3p LOH was not associated with aggressive biological behavior of gastrinomas or with poor prognosis of patients with gastrinoma. Similarly, 3p12 LOH (SRO) was not correlated with aggressive growth of tumors and/or liver metastases.Conclusion:Gastrinomas have a relative high frequency of 3p12 LOH suggesting this area may harbor putative tumor suppressor gene(s), which may play a role in the tumorigenesis, but not aggressiveness, of a subset of these tumors.

  • 标签: Chromosome 3p Gastrinoma Loss of heterozygosity Microsatellite instability Pancreatic neuroendocrine tumors
  • 简介:Aconitumbalfourii(Bruhl)Muk。(Ranunculaceae)是危及的药用的植物。自然人口为人口评价和精英germplasm的评估在西北Himalaya被调查。空铅的植被采样在支持A的区域用垂直的带横断方法被进行。balfourii。种密度和A的相对优势。balfourii与另外的高山的种类相比是低的。威胁地位在一个site-by-site基础上以及为全部西方的Himalaya被决定。A。balfourii是根据地理分发危及了并且极其根据丰富危及了通常被分类。我们发现天赋A的地理分发。balfourii将由于产地破坏正在减少。立即的校正管理措施为持续利用和种类的长期的保存被需要在野。

  • 标签: 濒危药用植物 喜马拉雅山脉 生态功能 乌头 西北 濒危物种
  • 简介:由地志的特征散布飞机嘘波浪在一分层横着各向同性(TI)一半空间被使用一个间接边界元素方法(IBEM)调查。第一,反飞机分层的TI一半空间的动态僵硬矩阵被建立,免费的地被使用直接僵硬方法解决。然后,草地函数为在分层的TI一半空间对一根使倾向的线起作用的一致地分布式的负担被导出,散布的地与推出的草地函数被构造。最后,免费的地被加到散布的获得全球动态回答。方法被把结果与出版的各向同性的作比较验证。两个都,不变、短暂的动态回答被评估并且讨论。在频率领域的数字结果证明为TI媒介的表面运动能与为各向同性的案例的那些显著地不同,它强烈依赖于anisotropy性质,事件角度和事件频率。在时间领域的结果证明材料anisotropy在最大的持续时间和时间历史的最大的振幅上有重要效果。

  • 标签: 横观各向同性 层状半空间 平面SH波 地形特点 特征对 衍射
  • 简介:Handwrittensignaturerecognitionispresentedbasedonananglefeaturevectorbyusingtheartificialneuralnetwork(ANN)inthisresearch.Eachsignatureimagewillberepresentedbyananglevector.ThefeaturevectorwillconstitutetheinputtotheANN.Thecollectionofsignatureimagesisdividedintotwosets.OnesetwillbeusedfortrainingtheANNinasupervisedfashion.TheothersetwhichisneverseenbytheANNwillbeusedfortesting.Aftertraining,theANNwillbetestedbyrecognizingthesignatures.Whenasignatureisclassifiedcorrectly,itisconsideredcorrectrecognition,otherwiseitisafailure.Theachievedrecognitionrateofthissystemis94%.

  • 标签: 人工神经网络算法 离线签名识别 特性 特征向量 监督方式 ANN
  • 简介:AbstractObjective:The treatments and prognoses of high-risk and low-risk basal cell carcinomas are quite different. This study aimed to examine the dermoscopic features of basal cell carcinomas and assess the association between the features and basal cell carcinomas recurrence risks in a Chinese population.Methods:Patients with histopathologically confirmed basal cell carcinomas examined from March 2016 to April 2020 were enrolled. The dermoscopic features were evaluated, and the correlations between these features and the histological types and recurrence risks were assessed.Results:The study cohort comprised 119 Chinese patients with a total of 119 skin lesions. The most common dermoscopic feature of basal cell carcinomas was the absence of a pigment network (119/119, 100%), followed by shiny white streaks (105/119, 88.24%), blue-gray ovoid nests (99/119, 83.19%), multiple blue globules (78/119, 65.55%), and arborizing vessels (78/119, 65.55%); yellow-white structures were present in 29/119 lesions (24.37%). Leaf-like and spoke-wheel areas were significantly associated with superficial basal cell carcinomas (P < 0.001), while arborizing vessels (P < 0.001), blue-gray ovoid nests (P < 0.001), and ulceration (P < 0.05) were significantly associated with nonsuperficial basal cell carcinomas subtypes. The dermoscopic features of the high-risk and low-risk groups exhibited considerable overlap; however, the respective independent predictive factors for a high and low risk of basal cell carcinomas recurrence were short fine telangiectases (P < 0.05) and blue-gray ovoid nests (P < 0.05).Conclusion:Dermoscopy provides important information about basal cell carcinomas and is helpful in differentiating superficial basal cell carcinomas from other subtypes. The dermoscopic vascular structures and blue-gray ovoid nests play a crucial role in evaluating the basal cell carcinomas risks preoperatively.

  • 标签: basal cell carcinoma dermoscopy histopathology recurrence risk skin cancer
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  • 简介:Theresultsofatheoreticalstudyontheinfluenceofstrengthofinterphaseboundariesinmetal—ceramiccompositeonmacroscopicalcharacteristicsofcompositeresponsesuchasstrength,deformationcapacity,fractureenergyandfracturepatternarepresented.Thestudywasconductedbymeansofcomputer-aidedsimulationbymeansofmovablecellularautomatonmethodtakingaccountofadeveloped'mesoscopical'structuralmodelofparticle-reinforcedcomposite.Thestrengthofinterphaseboundariesisfoundtobeakeystructuralfactordeterminingnotonlythestrengthpropertiesofmetal—ceramiccomposite,butalsothepatternandrateoffracture.Theprinciplesforachievementofthehigh-strengthvaluesofparticle/binderinterfacesinthemetal—ceramiccompositionduetotheformationofthewidetransitionzones(areasofvariablechemicalcomposition)attheinterphaseboundariesarediscussed.Simulationresultsconfirmthatsuchtransitionzonesprovideachangeinfracturemechanismandmaketheachievementofahigh-strengthandahighdeformationcapacityofmetal—ceramiccompositepossible.

  • 标签: 陶瓷复合材料 金属陶瓷 相界面 断口特征 力学性能 颗粒增强复合材料
  • 简介:轻油从的Geochemical作文特征在Chepaizi的西方第三级在Junggar盆高举,西北中国,从油源于的biodegraded的那些是不同的在来自象Chepaizi和Xiaoguai油矿那样的一些邻近的油领域的学习区域和原油二叠。在学习区域点亮油的油来源关联表演从侏罗记与导出煤的油让类似的n链烷和isoprenoid分发模式和碳同位素作文,并且与白垩纪来源一起在biomarker作文特征上显示明显的差异摇摘录,推断他们可能是从侏罗记煤措施和白垩纪来源的混合的油,这摇。在这研究,从白垩纪,来源和井白族2的第三级的原油的混合特征从侏罗记和白垩纪来源岩石或原油与导出煤的油的geochemical数据结合了,很好,白族8被调查。在混合的原油的二来源的比例被估计,并且在学习区域的水库的烃累积模式被建立。

  • 标签: 准噶尔盆地 原油特征 中国西北 轻质原油 隆起 原油地球化学特征
  • 简介:AbstractNonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, placing an increasing burden on human health. NAFLD is a complex multifactorial disease involving genetic, metabolic, and environmental factors. It is closely associated with metabolic syndrome, obesity, and type 2 diabetes, of which insulin resistance is the main pathophysiological mechanism. Over the past few decades, investigation of the pathogenesis, diagnosis, and treatments has revealed different aspects of NAFLD, challenging the accuracy of definition and therapeutic strategy for the clinical practice. Recently, experts reach a consensus that NAFLD does not reflect the current knowledge, and metabolic (dysfunction) associated fatty liver disease (MAFLD) is suggested as a more appropriate term. The new definition puts increased emphasis on the important role of metabolic dysfunction in it. Herein, the shared features and potential changes in epidemiology, pathophysiology, diagnosis, and pharmacotherapy of the newly defined MAFLD, as compared with the formerly defined NAFLD, are reviewed for updating our understanding.

  • 标签: Nonalcoholic fatty liver disease Metabolic (dysfunction) associated fatty liver disease Epidemiology Pathophysiology Diagnosis Pharmacotherapy
  • 简介:AbstractBackground:The importance of identifying osteoporotic vertebral endplate or/and cortex fracture (ECF), which primarily includes endplate fracture (EPF) and vertebral anterior cortex buckling, has been recognized. However, some old traumatic ECFs with healing process in the elderly may be mistaken as osteoporotic. This study analyzes the radiological features of traumatic EPF.Methods:This was a retrospective analysis of 194 spine trauma patients with 263 vertebral fractures (mean age: 42.11 ± 9.82 years, 118 males and 76 females). All patients had traumatic EPF identified by X-ray/CT/MRI.Results:The involved vertebra was mostly L1 (29.7%), followed by T12 and L2. Except EPFs involved both superior and inferior endplates (12.6%), only 1.9% involved inferior endplate alone, with the majority involved superior endplate. If each endplate was divided into five segments of equal lengths (from anterior to posterior: a1, a2, m, p2, p1), the most depressed point of superior EPFs was mostly at segment-a2 (approximately 45%), followed by segment-a1 (approximately 20%) or segment-m (approximately 20%), and very rarely at segment-p1. The upper 1/3 of anterior vertebral wall was more likely to fracture, followed by middle 1/3 of anterior wall. For posterior vertebral wall fracture, 68.5% broke the bony wall surrounding the basivertebral vain. 58.6%, 30.0%, and 11.4% of vertebral fractures had <1/5, 1/5-1/3, and >1/3 vertebral body height loss. As the extent of vertebral height loss increased, the chance of having both superior and inferior EPFs also increased; however, the chance of having inferior EPF alone did not increase.Conclusion:Traumatic EPF features are characterized, which may help the differentiation of traumatic and osteoporotic EPFs.

  • 标签: Spine Vertebral fracture Endplate Traumatic Vertebral cortex
  • 简介:At19:33p.monSeptember27,2003,anearthquakewithM7.9occurredintheRussiaMongolia-ChinaboundaryRegion.ItwasstronglyfeltintheAltayregionofXinjiang.Thelossescausedbytheearthquakewas76millionyuan(RMB).Someinformationabouttheearthquakewasoutlined,includingbasicparameters,focalmechanism,evaluationofearthquakedisasterlossesandsoon.Thesatelliteremotesensinginformationworkedinitialanalysisfordeformationofgroundandfailurephenomenon.

  • 标签: 俄罗斯-蒙古-中国 边界地区 地震强度 震源机制 遥感观测 构造环境
  • 简介:ThePhlaythonglargeirondepositinShampasakofsouthernLaos,islocatedintheKonTummicroblock(Fig.1A),central-southernpartoftheIndo-Chinablock,andthegeographiccoordinateofthecentralminingareais14°43′04″Nand106°07′02″E.Intensivetectonicandmagmaticactivitiesofmultipleperiodsdevelopedinthisregion,especiallyinMesozoicandCenozoic,whichareclosely更多还原

  • 标签: 地质特征 成矿作用 矿床成矿 老挝 铁矿 类型
  • 简介:ThedistributionalfeaturesoftemperatureandsalinityinthenorthernTaiwanStraitshavebeenanalyzedbasedontheCTDdataduringFebruary-March,1998.Thecharacteristicsoftemperatureandsalinityaresummarizedasfollows:(1)thereexistsacoastalwateralongthewesterncoastoftheTaiwanStraits,withlowtemperatureandlowsalinityattheupperlayer;(2)ahightemperatureandhighsalinitywatertongueextendsnortheastwardalongtheeasterncoastoftheTaiwanStrait.

  • 标签: temperature SALINITY northern TAIWAN STRAITS distribution
  • 简介:AbstractThis study aims to investigate cases of human plague in the Inner Mongolia Autonomous Region (IMAR), China, and to inform the development of plague prevention and control strategies. On 12th of November 2019, two herdsmen from Sunitezuo Banner, Xilingol League were diagnosed with pneumonic plague in Beijing, China. On November 16th, one resident of Xianghuang Banner, Xilingol League was diagnosed with bubonic plague in Huade County Hospital, Ulanqab, China. On 27th of November, one resident of Siziwang Banner was diagnosed with bubonic plague. In total, 78 close contacts were monitored over a period, but none of them developed symptoms. Plague outbreaks in animals had been reported in Sunitezuo Banner, Xianghuang Banner, and Siziwang Banner in 2019. Two of the four cases were related (husband and wife), but not the other two. All the cases may be associated with contact with rodents (hare) or infected fleas. The cases highlight the importance of early identification of plague cases in humans in order to stop further infection. This demonstrates the value of monitoring and ongoing vigilance on endemic diseases, the importance of updating medical training and raising public awareness about infectious diseases that even have not been observed over decades.

  • 标签: Plague Epidemiology Inner Mongolia Bubonic plague Pneumonic plague
  • 简介:AbstractObjective:To assess the clinical features of fetal growth restriction (FGR) in women with hypertensive disorders of pregnancy in China.Methods:This is a retrospective cohort study. The clinical data of 4 451 women with hypertensive disorders of pregnancy were retrospectively collected from 11 tertiary hospitals across ten provinces in China during January 2015 to December 2015. The mean maternal age was (31.0±5.4) years old. Participants were divided into FGR group (n= 670) and non-FGR group (n= 3 781). The incidence and clinical features of FGR, and its correlation with gestational age, previous FGR history, 24-hour urinary protein excretion, and hemolysis, elevated liver enzyme and low platelet count (HELLP) syndrome were analyzed. Student’s t-test and Chi-square test were used when comparing clinical features between FGR and non-FGR groups.Results:The overall incidence of FGR was 15.1% (670/4 451). The FGR incidence was 22.4% (433/1 937) in women with severe preeclampsia and 18.6% (68/365) in women with chronic hypertension with superimposed preeclampsia, respectively. FGR was more prevalent in women who had preterm births than those who had term births (22.8% (432/1 898) vs. 9.3% (238/2 553), P < 0.001). It was also more prevalent in women with early-onset preeclampsia than those with late-onset preeclampsia (18.4% (189/1 025) vs. 14.0% (481/3 426), P= 0.001). Women with a previous FGR history had a significantly higher FGR incidence than those without an FGR history (66.7% (4/6) vs. 15.7% (250/1 596), P= 0.007). The presence of abnormal results of the umbilical artery Doppler (13% (87/670) vs. 2.4% (89/3 781), P < 0.001) and the middle cerebral artery Doppler (3.3% (22/670) vs. 0.4% (15/3 781), P < 0.001) was higher in the FGR group compared with the non-FGR group, while the presence of increased uterine artery resistance was not statistically different (1.5% (10/670) vs. 0.8% (29/3 781), P= 0.072). The FGR group delivered earlier than the non-FGR group ((35.3±3.0) weeks vs. (36.4±4.3) weeks, P < 0.001) with lower birth weight (1 731.0±574.5) g vs. (2 753.9±902.1) g, P < 0.001, higher fetal or neonatal death (9.4% (63/670) vs. 4.2% (157/3 781), P < 0.001), and higher cesarean section rate (82.5% (553/670) vs. 70.2% (2 656/3 781), P < 0.001). In the FGR group, more neonates had 5-minute Apgar score ≤7 (7.9% (53/670) vs. 3.9% (149/3 780), P < 0.001), with higher neonatal intensive care unit admission rate (48.1 % (322/670) vs. 23.3% (881/3 781), P < 0.001). More cases of HELLP syndrome occurred in the FGR group (6.9% (46/670) vs. 3.2% (122/3 781), P < 0.001). Women with FGR had heavier 24-hour urinary protein excretion than those without FGR ((3.9±3.7) g vs. (3.1±4.2) g, P= 0.005).Conclusion:In pregnancies with hypertensive disorders, increased risks of FGR are associated with preterm birth, birth before 34 weeks, and a previous FGR history. FGR is related to higher occurrence of abnormal uterine artery Doppler and umbilical artery Doppler. When hypertensive disorders is complicated by FGR, there appears to be higher maternal morbidity including higher rate of HELLP syndrome, cesarean section, and heavier proteinuria, as well as worse neonatal outcomes.

  • 标签: China Fetal growth restriction Hypertension Pregnancy-induced Pre-eclampsia Incidence
  • 简介:自从他们在东北西藏的高原在查卡金海·莱克区域附近充当对tectonics和气候变化的小规模的似地球形状的单位回答,这篇文章试图学习冲积扇子的geomorpometric特征。我们份量上提取了似地球形状的参数,例如表面区域和邻近QinghaiNan掸人和Ela掸人的冲积扇子的斜坡。在查卡·莱克的冲积扇子划分区域,QinghaiNan掸人的南方,由一个小区域和短长度被展示,但是最大的斜坡。在Ela掸人区域的冲积扇子的似地球形状的参数在尺寸是中间的,并且在金海·莱克的冲积扇子划分QinghaiNan掸人的区域北方有最轻轻的斜坡。和地区性的指责活动分析,我们建议有在QinghaiNan掸人的南方的高斜坡的冲积扇子被沿着QinghaiNan掸人差错,和Ela掸人差错地区戏的罢工滑倒运动指责的颠倒主要控制一个弱角色。由于活跃差错的缺乏,相反,QinghaiNan掸人的金海·莱克区域北方附近的冲积扇子仅仅对地区性的侵蚀,交通,和免职过程作出回应,从而形成相对轻轻的似地球形状的单位。

  • 标签: 青藏高原东北部 青海湖地区 冲积扇 地貌单元 断层活动
  • 简介:为合成的孔雷达(SAR)形象与高效率设计察觉算法为操作符SAR自动目标识别(ATR)系统是必要的。这个工作放弃在在许多传统的察觉算法做的SAR形象访问每个象素的察觉策略,并且介绍gridding和不同质地特征的熔化想法认识到快目标察觉。它第一个格子原来的SAR形象,产出一套格子被分类进喧嚷格子和目标格子,然后计算质地在每个格子展示。由熔化计算结果,包含调遣目标的潜力的目标格子是坚定的。双阀值分割技术在目标格子上被强加获得兴趣的区域。熔化质地展示,包括本地统计特征和灰色级的同现矩阵(GLCM),被调查。我们的建议算法的效率和优势被用真实SAR数据与存在快察觉算法作比较测试并且验证。从实验获得的结果显示我们的学习的有希望的实际申请价值。

  • 标签: 合成的孔雷达形象 目标察觉 质地特征 GRIDDING 灰色级的同现矩阵 熔化