简介：　　 [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月～ 2020年 1月我院收治的溃疡性结肠炎患者 80例，随机分为两组，每组各 40例，两组患者均予常规对症治疗，同时两组均予美沙拉嗪缓释颗粒，观察组同时加用双歧三联活菌胶囊，治疗后比较两组患者治疗后的临床疗效，以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%，显著高于对照组的总有效率 70.00%，两组疗效比较差异具有显著性（ P<0.05）。治疗后，两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低（ P<0.05）。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组（ P<0.05）。观察组患者治疗后的临床症状积分为（ 2.56±0.85）分，与治疗前及对照组比较，差异有统计学意义（ P<0.05）。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切，且可以抑制炎症反应，值得临床推广和应用。  　　 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子  　 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.

简介：[摘要]目的 探讨急性牙髓炎一次性根管治疗的临床疗效。方法 调查对象是2018年1月—2019年1月诊断为急性牙髓炎的

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简介：　　【摘 要】目的：研究小切口阑尾炎切除术治疗阑尾炎的临床疗效。方法：选取 2018年 12月 -2020年 1月 70例阑尾炎患者作为研究对象，抽取 35例作为观察组，另根据配对原则抽取 35例作为对照组。对照组采用传统切口阑尾切除术，观察组采用小切口阑尾炎切除术。对比手术时间、术中出血量及术后并发症发生率。结果：观察组手术时间短于对照组，术中出血量及术后并发症发生率少于对照组，对比差异有统计学意义（ P<0.05）。结论：小切口阑尾炎切除术治疗阑尾炎具有显著效果，可缩短治疗时间，减少术中出血及术后并发症对患者造成的影响，值得临床推广。  　　【关键词】小切口阑尾炎切除术；阑尾炎；并发症  Objective: To study the clinical effect of small incision appendectomy in the treatment of appendicitis. Methods: 70 cases of appendicitis patients from December 2018 to January 2020 were selected as the research object, 35 cases were selected as the observation group, and 35 cases were selected as the control group according to the matching principle. The control group was treated with traditional incision appendectomy, and the observation group was treated with small incision appendectomy. The operation time, intraoperative blood loss and postoperative complications were compared. Results: the operation time of the observation group was shorter than that of the control group, the intraoperative blood loss and the incidence of postoperative complications were less than those of the control group, the difference was statistically significant (P < 0.05). Conclusion: small incision appendectomy in the treatment of appendicitis has a significant effect, can shorten the treatment time, reduce intraoperative bleeding and postoperative complications on patients, which is worthy of clinical promotion.

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简介：【摘 要】目的：探讨急性胰腺炎患者在治疗期间采用循证护理的临床效果。方法：将我院 2018年 12月 -2019年 2月收治的 100例急性胰腺炎患者进行研究分析，所有患者分为观察组与对照组，对照组采用常规护理，观察组采用循环护理，比较两组的临床护理效果。结果：比较观察组与对照组患者护理前后疼痛评分情况，护理前，两组患者的疼痛评分差异性小 P＞ 0.05，护理后，观察组的疼痛评分显著低于对照组，差异对比度大，统计学有比较意义 P＜ 0.05。结论：急性胰腺炎实施循证护理可帮助患者缓解疾病的疼痛感，并取得满意的效果，可被临床推广使用。

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