简介:Vasopressinistheantidiuretichormoneofhumans.Itisanonapeptidesynthesizedinthemagnocellularneurortsofthesupraopticnucleusofthehypothalamus.Thegeneencodingalargeprecursorprotein,includingvasopressinanditsearrierproteinneurophysin,islocatedonctuvmosome20.q]aelargemoleculeiscleavedasitistransportedintraneumnallytotheposteriorpittfitmy,wherethehormoneanditsneurophysinarestoredbeforetheirreleaseintotilesystemiccirculation,govemedmainlybychangesinbloodosmolalitv.
简介:Pregnancyprofoundlyaffectscarbohydratemetabolism.Thesechangesareimportantinwomenwithdiabetes(typicallytype1,butmoreyoungtype2patientsarebeingencountered)whoareplanningpregnancy,andinwomenwhodevelopgestationaldiabetesmellitus(GDM-glucoseintolerancefirstrecognizedduringpregnancy).Inallcases,acompmherlsiveapproachinvolx4ngexpertiseinobstetrics,diabetology,nursinganddieteticsishighlydesirable.
简介:Failureofthethyroidglandrequiresthyroidhormonereplacementtherapy,whichisrelativelyeasilyadjustedtoreplicatethenormalphysiologicalstatebymonitoringplasmalevelsofthyroxineand/orthyroid-stimulatinghormone.Incontrast,failureofpancreaticβ-eellsrequiresinsulintherapy,andoptimalreplacementrequiresmonitoring,notoftheabsenthormone(insulin),butofitsmajorsubstmte(glucose).
简介:Erectilefailureisparticularlyconmaoninmenwithdiabetes;itaffectsupto30%,andtheprevalenceincreasesfurtherwithage,durationofdiabetes,andthepresenceofmicrovascularandn'kacrovascularcomplications.Itcanbedistressingforboththemanandhispartner.Thereisnowincreasingawarenessoftheimportanceoftheproblem,andtheincreasedefficacyandavailabilityoftreatmentmakesitcorrectableinmorethan80%of
简介:DiabetesMellitus(DM)isametabolicdisorderresultingfrommanyfactorsandcharacterizedbychronicelevatedbloodsugar.DM'scausesarenownotabsolutelyknown,butitisknownasasyndromeassociatedwithheredity,self-immuneandenvironmentalfactors.IntraditionalChinesemedicine,DMbelongstothecategoryof"XiaoKe"andistypedinto"ShangXiao',"ZhongXiao"and"XiaXiao"inthelightofthediseasedlocation.
简介:Groningen:StyxPublications,1999.ISBN9056930311.Hfl.85,-.Asthetitlemightsuggest,thesecollectedessayspurporttodiscussanddifferentiategenrefromtypeinapre-moderncontextofculturesthathavewrittenrecords.However,thisisnotthecase,forastheeditorspointoutinthealltoobriefpreface,theessayscollectedinthisvolumemayatfirstsightseemstrangeand,indeed,abaroqueassemblageofapparentlytotallyunrelatedtopics(p.vii).Theygoontoclaimthat'thereseemstobeadoubleredthreadrunningthroughthismulti-colouredcloth.'Thesethreadsareidentifiedas...
简介:Anovelpre-ionizationschemeofhelicaltransverse-pulsedpre-ionizationinalongitudinaldischargeCO2laserispresented.Thelasertubeismadeofglasswithinnerdiameterof7.5mmanddischargelengthof50cm.Thelaserperformancecharacteristicsasfunctionsofparameters,suchaspressure,chargingcapacitanceandappliedvoltage,areinvestigated.Comparedwiththesamelaserstructurewithoutpre-ionization,themaximumpulseenergyimprovesby23%,theoptimumelectro-opticalefficiencyincreasesby31%,andthespecificoutputenergyreaches26J/(L·atm).
简介:Pre-mRNAsplicingisafundamentalprocessrequiredfortheexpressionofmostmetazoangenes.Itiscarriedoutbythespliceosomethatcatalyzestheremovalofnon-codingintronsequencestoligateexonsintomaturemRNApriortotransportandtranslation.Thepurposeofourstudyistoexplorewhethertheinvitrounlabeledpre-mRNAsplicingassaycouldbeperformedasanalternativemethodofsplicingreactionotherthantheradiolabeledone.Twodifferentsplicingmethodsinvitro,Plabeledandunlabeledpre-mRNAasthesubstratesinthereaction,wereinvestigated.TheradiolabeledproductswerevisualizedbyautoradiographywhiletheunlabeledproductswereobservedbyEthidiumBromide(EB)staining.Asaresult,althoughtherearemoreunspecificbandsintheEBstainingassaythan32Plabeledone,theRNAproductsofinvitrosplicingcouldbeobservedclearly.Thissuggeststhattheunlabeledpre-mRNAsplicingassaycanbeanoptionalsubstitutionfortheisotope-labeledassay.
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简介:Thedistributionofacetylcholinesterase(AChE)-positivestructuresinthedevelopingratspinalcordwasstudiedwithAChE-histochemistry.AChE-positiveperikaryawerefirstseenonembryonicday14(E14)intheventrolateralportionofthespinalcord.Fromthattimeonward.AChE=containingcellsappearedgraduallyintheintermediategray,dorsalhornandlateralspinalnucleusofthespinalcordinaventral-to-dorsal,andlateral-to-medialorder.Noobviousrostral-to-caudalsequencewasfound.Atbirth,thedistributionpatternofAChE-positiveperikaryawasbasicallysimilartothatinadults.AfterbirthadramaticincreaseintheAChEstainingintensityextendedfrompostnatalday5(P5)topostnatalday21(P21),Inaddition,twophasesoftransientAChEstainingwereobservedintheexternalsurfaceofthedorsalhornfromembryonicday15(E15)toembryonicday21(E21)andinthemarginallayerfromembryonicday21(E21)topostnatalday14(P14),respectively.
简介:ThesynchrodoublepulsesignalmodeisfreuqentlyusedinShortBaseLine(SBL)underwaterpositioningsystemsoastoobtaintheinforma-tionofbothdistanceanddepthofatargetsimultaneously.Howerer,thissignalmodealsobringsaboutrangingindistinctnessresultinginashorterpositioningdistancemuchlessthanthatlimitedbytheperiodofthesynchrosignal.Thispaperpresentsahardwaredistance-gatedataacquiringscheme.Itputstheoriginaldatasenttothecomputerinorderof"directfirstpulse—depthinformationpulse(orfirstpulsereflectedbywatersurface)…"toguaranteetheeffectivepositioningdistanceofthesystem.Ithastheadvan-tageofreducingtheprocessingtimeofthecomputerthusensuringtherealtimefunctioningofthesystem.Afigureoftheorbitofanunderwatermovingtargetmeasuredinpracticeisattachedtotheendofthepaper.
简介:Objective:Toobservethetherapeuticeffectofcombinedtreatmentofdiabetesmellitus(DM)anditscomplications.Methods:30casesofnoninsulindependentdiabetesweretreatedbyelectroacupuncture(EA)ofTianzhu(天柱BL10),Dashu(大杼BL11),Fengmen(风门BL12),Jueyinshu(厥阴俞BL14),etc,massageattheacupointsalongtheBladderMeridian,pointinjectionofVitaminB1,B6,B12pluslidocaineatNeiguan(内关PC6)andSanyinjiao(三阴交SP6,onceevery3days),cuppingandphysiotherapycomprehensively.Thetherapeuticeffectwasanalyzedafter40treatments.Results:Aftertreatment,ofthe30cases,23(76.7%)experiencedremarkableimprovementintheirsymptomsandtherest7(23.3%)hadimprovement,withthetotaleffectiveratebeing100%.Conclusion:TheabovementionedcombinedtreatmentmethodworkswellinimprovingclinicalsymptomsoftypeⅡDMpatients.