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简介:ObjectiveTotestCalciumion(Ca2+)flowattheheadandendofouterhaircells(OHCs)inrestingstateandinresponsetoNimodipinetreatment.MethodsNon-invasivemicro-testtechniqueswereusedtostudyCa2+inisolatedOHCsinadultguineapigs.ResultsFourtypesofCa2+transportwereidentifiedinOHCsonbasilarmembranetissuefragments:influxattheheadofwitheffluxatthebottom(type1):effluxattheheadofOHCswithinfluxatthebottom(type2);influxatthebothheadandbottom(type3);andeffluxatthebothheadandbottom(type4).However,onlytype1andtype3ofCa2+iontransportweredetectedinthecochlea.WeproposethatCa2+iontransportexistsinadultguineapigcochlearOHCsinrestingstateandisvariable.Ca2+flowinOHCcanbeinhibitedbyNimodipineinrestingstate.
简介:[摘要]:微视屏(Micro-lecture)“课微而不小”,它借助于现代化信息技术,通过5-10分钟的视屏短片把课本里的知识内容形象化、精确化、具体化,它的知识内涵非常和教学意义也非常重大,教学效果明显,微课能发挥学生的积极主动性,还能够辅佐学生课外英语自主学习,是一种新型的教育教学方式。
简介:摘要目的研究骨质疏松性椎体压缩骨折的Micro-CT影像学参数。方法以2016年1月至2017年1月我院收治的30例骨质疏松性椎体压缩骨折患者为研究组,另选取同期无骨质疏松骨折患者30例作为对照组,对比两组患者的Micro-CT影像学参数。结果研究组皮质骨、松质骨、骨小梁的骨密度均低于对照组,骨矿含量均低于对照组,与对照组相比存在显著差异(P<0.05)。结论骨质疏松性椎体压缩骨折Micro-CT影像学参数发现,骨密度和骨矿含量降低是椎体压缩骨折发生的主要原因,因此,预防骨密度和骨矿含量下降对骨质疏松性椎体压缩骨折具有重要的作用。
简介:锁泉华的microfibrous网络由8m(dia)的3vol.%组成镍microfibers被利用了骗诱100200mdia的30vol.%。多孔的Al2O3。ZnO和CaO然后被早期的湿受精方法高度驱散到骗诱的Al2O3的毛孔表面上。由于表面区域,毛孔尺寸/粒子尺寸,热传导性,和空体积的唯一的联合,当在甲醇蒸气改过使用了时,产生microfibrous催化剂composites提供了催化的床反应和利用效率的重要改进。粗略地甲酸盐的260mL/min,包括>70%H2,<5%公司和踪迹CH4,与>97%甲醇变换,能在我们骗诱的新奇microfibrous的1cm3床卷被生产在470湩瑡潩?潰祬敭r合成的ZnO-CaO/Al2O3催化剂?鑈я鑈я8
简介:Micro-arcoxidation(MAO)processwascarriedoutinanoptimizeddualelectrolytesystemtofabricateacompact,smooth,andcorrosionresistantcoatingonZK60Mgalloy.Themicrostructuralcharacteristicsofcoatingwereinvestigatedbyscanningelectronmicroscopy(SEM)coupledwithanenergydispersivespectrometer(EDS)andX-raydiffraction(XRD).Testofmasslosswasconductedata3.5%NaClsolutiontoassesstheresistancetocorrosion.ThebondingstrengthbetweenthecoatingandZK60substratewasevaluatedusingscratchexperiment.TheresultsrevealthatMgAl2O4andMgOarethemainphasesofceramiccoatingobtainedinthedualelectrolytesystem.Thecorrosionrateofcoatingpreparedintheoptimizeddualelectrolyteisonly0.0061gám-2áh-1,whichdemonstratesexcellentcorrosionresistance.Thisismainlyduetothecompact,uniformcoatingwithhighbondingstrength.
简介:目的利用新型纳米颗粒造影剂结合Micro-CT成像技术,建立小鼠肝脏成像方法,并用于肝脏肿瘤的活体成像。方法6只6-8周龄雄性C57BL/6J小鼠随机分成A组和B组,分别尾静脉注射纳米颗粒造影剂ExiTronnano1200050μL和100μL;在注射前、注射后3min、24h、7d、14d、28d和56d对所有小鼠肝脏进行Micro-CT活体扫描;分别在小鼠肝左叶和肝右叶内选取感兴趣区(ROI)进行灰度值分析,比较不同时间点肝组织对比度的变化。确定合适的造影剂剂量,尾静脉注射至3只雄性16月龄HBV转基因肝癌模型小鼠(C组),同上进行Micro-CT活体扫描,并于第56天全部安乐死后取肝脏观察病理学改变。结果A组和B组小鼠在注射不同浓度造影剂后,冠状位重建图像及肝脏感兴趣区的平均灰度值结果显示:肝脏实质造影后均比注射前明显增强,24h达到峰值,注射后56d内,小鼠肝脏感兴趣区的平均灰度值与注射前相比仍维持在较高的水平,B组显著高于A组(P〈0.01),确定后续实验采用B组造影剂剂量(100μL)。C组注射100μL造影剂后,各时间点均能比较清楚地看到肝脏癌性结节存在,病理学观察发现肝脏出现非典型增生,肿瘤细胞核大,染色质加深和肝细胞坏死。结论利用纳米颗粒造影剂结合Micro-CT成像技术,成功建立了小鼠肝脏活体成像方法,并可应用于肝脏肿瘤的活体成像研究。
简介:摘要目的研究舟月骨间韧带(SLIL)的形态和血供分布,并从解剖学角度探讨临床上SLIL损伤对其血供的影响及重建的方法。方法2018年10月至2018年12月,选取12例新鲜成人前臂标本,从尺动脉或桡动脉灌注明胶-氧化铅溶液,于Micro-CT下扫描,通过Mimics软件三维重建图像,观察SLIL在中立位的形态和韧带内滋养血管分布,测量韧带掌侧、背侧和近端的宽度、长度、厚度,测量SLIL内滋养血管入口处的解剖参数,并分析其与舟、月骨的血供关系。结果①数字化技术三维重建SLIL的大体形态并测量其解剖参数,近端长度均值最大,掌侧、背侧长度相近;韧带掌侧最宽,厚度最小,而背侧与近端在厚度与宽度上相近。②SLIL的近端无滋养血管分布,掌侧与背侧均有丰富的滋养血管分布,其血供分布差异无统计学意义(P>0.05)。③SLIL的掌侧与背侧内滋养血管从SLIL附着处进入舟、月骨内形成吻合。结论SLIL掌侧较宽且厚度小,从解剖学角度分析其较其它亚区更易损伤;其掌侧与背侧亚区均有丰富的血供且与舟、月骨内相吻合,而近端无血管分布,因此,掌、背侧韧带早期轻度损伤有一定的自我修复能力,而近端损伤则较难修复,韧带掌侧与背侧损伤对舟、月骨血供会产生一定影响。
简介:Overthelastdecade,computationalmethodshavebeenintensivelyappliedtoavarietyofscientificresearchesandengi-neeringdesigns.Althoughthecomputationalfluiddynamics(CFD)methodhasplayedadominantroleinstudyingandsimu-latingtransportphenomenainvolvingfluidflowandheatandmasstransfers,inrecentyears,othernumericalmethodsforthesimulationsatmeso-andmicro-scaleshavealsobeenactivelyappliedtosolvethephysicsofcomplexflowandfluid-interfaceinteractions.Thispaperpresentsareviewofrecentadvancesinmulti-scalecomputationalsimulationofbiomimeticsrelatedfluidflowproblems.Thestate-of-the-artnumericaltechniques,suchaslatticeBoltzmannmethod(LBM),moleculardynamics(MD),andconventionalCFD,appliedtodifferentproblemssuchasfishflow,electro-osmosiseffectofearthwormmotion,andself-cleaninghydrophobicsurface,andthenumericalapproachesareintroduced.Thenewchallengingofmodellingbiomi-meticsproblemsindevelopingthephysicalconditionsofself-cleanhydrophobicsurfacesisdiscussed.
简介:Hydrocarbonmicro-seepagecancauseoxidationreductionreactionsandproducealteredmineralsinsurfacesedimentsandsoil.Thetypicalalteredmineralsmappingbytheirdiagnosticspectralfeaturesonhyper-spectralimagesisanimportanttoolforthepetroleumexplorationindustry.Inthisstudy,theairbornehyper-spectraldatawereusedtoinvestigatethealteredmineralsinducedbyhydrocarbonmicro-seepagesbyspectralfeaturefitting(SFF)intheloesscoverageareaofXifengOilfield.Theresultsrevealthatthedistributionregionofthealteredmineralsinducedbyhydrocarbonmicro-seepageislargerthantheknownoilfieldexplorationarea.Thepotentialhydrocarbonmicro-seepageregionwasalsorevealedbythedistributionofalteredmineralsbesidestheknownhydrocarbonarea.Afastindexwasproposedbytheabsorptiondepthsofclayandcarbonatemineralsforassessmentofhydrocarbonmicroseepage.Anditgavemuchclearerboundariesforthehydrocarbonmicro-seepageintheloesscoverageareathanthosebythealteredmineralmapping.Inaddition,somefieldsampleswereanalyzedbyX-raydiffraction(XRD)andatomicabsorptionspectrophotometertovalidatetheresults.Withintheextentsofhydrocarbonmicro-seepage,therearelowercontentsofferricironandhighercontentsofcarbonatemineralsinthesesamples.Therefore,itissatisfactorytohavetheairbornehyper-spectraldatatooutlinetheextentsofhydrocarbonmicro-seepageforfurtherhydrocarbonexplorationintheloesscoveragearea.
简介:Anoveltwo-stagereductionprocessforsynthesisofultrafinenickelpowderwithahighpurityandlowdensityinafluidizedbedreactorhasbeendevelopedinthiswork.TherawultrafineNiOparticlesarefirstpre-reducedusinghydrogenatlowertemperatures(340-400℃),followedbyfurtherreductionathighertemperatures(500-600℃).Theself-agglomerationofNiparticlesformedduringlow-temperaturereductiondecreasesthesinteringactivityofthenewlyformedultrafineNiparticles,leadingtogoodfluidizationquality,evenforthesubsequenthigh-temperaturereductionprocess.TheagglomeratedNiparticleshaveahighNicontent(above99wt%),alowdensity(0.78g/cm~3)andauniformparticlesize(approximately100μm).Aconceptdesignforanoveltwo-stagefluidizedbedreactorprocessusedtoproducehigh-purityNipowderwasalsoproposed.Thisapproachmaybeextendedtothesynthesisofotherultrafine/nanosizedmetalsormetaloxidesthroughafluidizationmethod.
简介:ComparisonofmechanicalpropertiesinweldedjointforCO2arcweldingbyusingthemicro-sheartestandimpacttest¥ZhouLixia;WangShiyuanand?..
简介:Westudythedynamicbehaviorofaquartzcrystalresonator(QCR)inthickness-shearvibrationswiththeuppersurfacecoveredbyanarrayofmicro-beams(MBs)underlargedeflection.ThroughtakingintoaccountthecontinuousconditionsofshearforceandbendingmomentattheinterfaceofMBs/resonator,dependencesoffrequencyshiftofthecompoundQCRsystemversusmaterialparameterandgeometricalparameterareillustratedindetailfornonlinearandlinearvibrations.Itisfoundthatthefrequencyshiftproducesalittleright(left)translationforincreasingelasticmodulus(length/radiusratio)ofMBs.Moreover,thefrequencyright(left)translationdistancecausedbynonlineardeformationbecomesmoreseriousinthesecond-ordermodethaninthefirst-orderone.
简介:AnintegratedinvestigationwascarriedoutduringlateApriltolateMayof2014inthecoastalareaofSouthJiangsuProvincetounderstandtheearlydevelopmentofgreentideintheYellowSeaanddiscoverthetemporalandspatialdistributionofgreenalgalmicro-propagulesandmacroalgaeattheearlystageofgreentide.Theresultsshowedthatgreenalgalmicro-propagulesdistributedinallstationsfromlateApriltolateMay,andmicro-propagulesofhighdensity(>300ind.L?1)concentratedintheadjacentPorphyraaquaculturearea.Floatingmacroalgaewereinitiallyobservedinthenorthernsurveyareas,andincreasedgradually.ThedominantspecieswasU.proliferainthefloatingmacroalgae,rangingbetween90%and100%.Theseawatersurfacetemperatureandsalinityintheabovementionedtimeperiodweresuitableforthegrowthofmacroalgae.ThisworkcanhelpgovernmenttostrengthenmanagementtoreducethebloomsofmacroalgaeinthecoastalareaofSouthJiangsuProvinceandalsofacilitatethedecision-makingformanagersattheearlystageofgreentide.