简介：XinhuareportedthatChina'sMinisterofScienceandTechnologyheldtalksonDecember7withBillGatesinabidtobooststrategiccooperationbetweenChinaandtheBill

简介：AbstractSince its outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has strongly influenced the life of the general public around the world. Based on its fast spread and high mortality, there is a need for novel therapeutic treatments to overcome this global health crisis. While medicinal chemistry is focused on the development of highly selective and affine inhibitors toward a specific target enzyme, material science is focused on the development of nanomaterials for selective drug delivery. Based on the individual strengths, these disciplines could synergistically act together and help overcome the limitations of the respective approach. Herein, the combination of medicinal chemistry with material science to overcome health problems with the example of SARS-CoV-2 is critically discussed.

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简介：Inthelasttwoorthreedecades,physicalactivity(PA)hasgainedincreasingrecognitionasbeingessentialformaintaininggoodhealthandimprovingqualityoflifeforallages.Childrenhavetraditionallybeenactiveinbothfreeplayandorganizedsports.However,therehasbeenarecentdeclineinthePAlevelsamongchildrenforvariousreasons.Thislifestylechangehasresultedinincreasedobesityaccompaniedbyariseindiabetesandcardiovascularriskamongotherwisehealthychildren.Theselifestylechangeshavebeenshowntobeevenmoreaproblemwhenthechildisalreadyaffectedbyachronicdisease.Duetomedicallimitationsandcontraindications,muchcaremustbetakentomakecertainthatthesechildrenareinvolvedintheappropriatevolumeandintensityofexercise.Thetypeofactivitymustalsobegivencarefulconsiderationtoavoidundueriskforthechildwhomayhaveproblemssuchaspoorbalance,limitedstrength,poorvision,orcognitivedisability.FurthercomplicationsareeithercausedorexacerbatedbylackofsufficientPA.Theprioritybeyondconcernforsafetyshouldbefocusedonensuringthehighestqualityoflifepossible.ThepurposeofthisreviewistoexaminehowPAcanbenefitchildrenwithselectedchronichealthconditions.

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简介：长途旅行倒时差是一件让人头疼的事件。最近，科学家们找到了一种似乎会阻碍机体和大脑快速适应新时区的荷尔蒙。这种荷尔蒙未在体内发生作用的老鼠能轻而易举地大幅调整时差。

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简介：AbstractThe developmental origins of health and disease theory states that environmental stresses during the early stages of life influence health and risk of developing non-communicable diseases throughout the lifespan of an individual. Developmental plasticity is thought to be a possible underlying mechanism. Here, I discuss a contrasting but complementary genetic hypothesis regarding the developmental origins of health and disease theory: crosstalk between the genomes of the parents and offspring is responsible for shaping and adapting responses to environmental stresses, regulating early growth and predisposition to non-communicable diseases. Genetic variants that are beneficial in terms of responses to early life stresses may have pleiotropic detrimental effects on health later in life, which may change the allele frequencies driven by selection on a population level. Genetic studies on the cohort of children born after assisted reproduction could provide insight regarding the genetic mechanisms of the developmental origins of health and disease theory.

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简介：Thispaperdealswiththeissueofprioritysettinginhealthcareunderuncertaintiesabouttheseverityoftheillnessandtheeffectivenessofmedicaltreatment.Weexaminetheeffectofadiseaseuncertainty(atreatmentuncertainty)ontheallocationofhealthcareresourcesinthepresenceofatreatmentrisk(adiseaserisk)andidentifypreferenceconditionsunderwhichthesocialplannerallocatesmoreresourcestohigherriskpopulation.Weallowforthesimultaneouspresenceoftworisksandinvestigatethejointeffectoftwo-sourceuncertaintiesonhealthcareallocationwhenthetworisksareeithersmallorpositivelyquadrantdependent.Theeffectofinequalityaversiononhealthcareallocationisalsoanalyzedbyintroducinganequityweightingfunction.Ourworkextendsthepreviousmodelofhealthcareprioritytotwo-riskframeworkandprovidesnewinsightsintotheproblemofhealthcaredecisionmakingunderuncertainty.

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简介：ThetraditionalChinesemedicine(TCM)theoryoftraditionalChinesehealthexercise(TCHE)isanalyzed.TheeffectofmeridiansandacupointscontainedinTCHEissummarized,thetreatmentmethodsoftonifyingdeficienciesandreducingexcessesappliedinTCHEarediscussed,theregulationofZang-fuorgansareemphasized,andtheleadingroleofQiisintroduced.TheexerciseprescriptionandpropertimingofTCHEaredescribedandreported.TCHEs,suchasBaduanjin,Liuzijue,andTaiChi,possessstrongTCMcharacteristics.

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简介：Withcontinuouslystrengthenedcharacteristicssuchaswhole-familymigrationandlong-termresidenceofthemigrantpopulation,theirneedsforbasicpublichealthandfamilyplanningservicesbecomemoreurgent.However,serviceutilizationhasbeenrelativelyinadequateandpressureonlocalpublicserviceandsupplyissubstantialinareaswithhighmigrantpopulationdensity.Inrecentyears,

简介：AbstractObjective:To summarize the main updated evidence about the health effects of air pollution, with a special focus on Southern Europe.Data sources:Literature was obtained through PubMed Central and the official websites of European Agencies and Scientific Societies.Study selection:Recent shreds of evidence about the health effects of air pollution coming from international reports and original research were collected and described in this review.Results:Air pollution is an avoidable risk factor that causes a huge burden for society, in terms of death, health disorders, and huge socio-economic costs. The southern European countries face a more threatening problem because they experience the effects of both anthropogenic pollutants and natural dusts (particulate matter [PM]). The European Environment Agency reported the number of premature deaths in the 28 countries of the European Union attributable to air pollutant exposure in the year 2016: 374,000 for PM2.5, 68,000 for nitrogen dioxide, and 14,000 for ozone. In Italy, time series and analytical epidemiological studies showed increased cardiorespiratory hospital admissions and mortality, as well as increased risk of respiratory diseases in people living in urban areas.Conclusions:Based on abundant evidence, the World Health Organization, which hosts the Global Alliance against Chronic Respiratory Diseases (GARD), the scientific respiratory societies, and the patients’ associations, as well as others in the health sector, must increase their engagement in advocacy for clean air policies.