简介:CaiFangwasborninSeptember1956inBeijing.HegraduatedinRenminUniversityofChinaandthengothisdoctorateineconomicsfromtheGraduateSchoolofChinaAcademyofSocialSciences(CASS).Now,heisCASSAcademicCommitteeMemberandDirectorGeneralofInstituteofPopulationandLabourEconomics.In1998,hereceivedthenationaltitleofYoungExpertwithOutstanding
简介:ObjectiveTostudytheinfluenceofJiangTangFangLongformulaoninsulinproductionandfunctioninananimalmodelofdiabetichearingloss.MethodsWistarrats(n=60)wererandomlydividedinto6groups(10ineach)toreceivenotreatment(thenormalcontrol,GroupA),ortoreceiveintra-peritoneal55mg/kgstreptozotocinwith(GroupsC,DandE)orwithout(GroupB)subsequentJiangTangFangLongformulatreatmentatvariousdosesorYuLongWantreatment(GroupF).After60days,fastingbloodglucose(FBG),bodyweight(BW)andfastinginsulin(FINS)wererecordedandtheHOMA-IRandHOMA-βcalcu-lated.Insulinexpressioninpancreatictissueswasmeasuredbyradioimmunoassay.ResultsComparedwithanimalsthatreceivedstreptozotocinwithoutrescuetreatment(GroupB),animalsthatreceivedhigherdosesofJiangTangFangLongformula(GroupsDandE)showedimprovedindicesofdiabetesmanifestation(P<0.05)andimprovedHOMA-β(P<0.05)inadose-dependentmanner,aswellasimprovedinsulinexpressioninpancreaticislets(P<0.05).ThedifferencebetweenlowdoseJiangTangFangLongformulatreatment(GroupC)andGroupBwasnotsignificant(P>0.05).ConclusionOurresultssuggestthatJiangTangFangLongformulamayimprovepancreaticβ-cellsfunctionwhichmayexplainitsefficacyintreatingdiabetichearingloss.
简介:ObjectiveTostudytheefficacyandsafetyoftheJiangTangFangLongJiaoNang(HypoglycemicAnti-DeafnessCapsule)intreatingnon-insulindependentdiabetesmellituswithhearingloss.MethodsTwohundredninetysixpatientswithnon-insulindependentdiabetesmellitusandhearinglosswererandomlyassignedtoatreatmentgroup(n=164,208ears)andacontrolgroup(n=132,184ears).PatientsinthetreatmentgroupweretreatedwiththeJiangTangFangLongJiaoNangandsupplementherbalpreparationsasindicatedbytraditionalChinesemedicinedialecticalassessment,whilecontrolpatientsreceivedglibenclamideandconventionaltreatmentsfordeafness.Hearing,fastingbloodglucose(FBG),post-prandialbloodglucose(PBG),24hoururinesugar,plateletfunctionindices,bloodsuperoxidedismutase(SOD)andlipidperoxides(LPO)levels,andsymptomimprovementwerecomparedbetweenthetwogroups.ResultsTherateofhearingimprovementwas56.7%forthetreatmentgroupand26.6%forthecontrol.FBG,PBGand24hoururinesugarimprovedinbothgroups,butthelasttwoweresuperiorinthetreatmentgroupcomparedtothecontrol.Symptomsimprovementwasalsosuperiorinthetreatmentgroupcomparedtothecontrol.InpatientsreceivingJiangTangFangLongJiaoNangtreatment,plateletfunctionindices,SODandLPOwereallimproved,whileonlyLOPimprovementwasnoticedincontrolpatients.Noacuteorlong-termtoxicitywasdemonstratedfortheJiangTangFangLongJiaoNanginanimaltests.TheJiangTangFangLongJiaoNangloweredbloodglucoseandserumtriglyceridesinaratmodelofalloxan-induceddiabetes.ConclusionTheJiangTangFangLongJiaoNangiseffectiveinimprovinghearinganddiabeticindicesindiabeticpatientswithdeafness,withoutsignificantsideeffects.
简介:你知道不莱梅吗?噢——它是一个美丽快乐的地方。不莱梅在哪儿呢?噢——有梦想的地方就有不莱梅。没错儿,不莱梅这个地方,早就存在于“很久很久以前”的童话里了……